CAS 168828-82-8

(5R)-3-(3-Fluoro-4-(4-morfolinil)fenil)-5-idrossimetil-2-ossazolidinone

Descrizione:

La sostanza chimica nota come (5R)-3-(3-fluoro-4-(4-morfolinil)fenile)-5-idrossimetil-2-ossazolidinone, con numero CAS 168828-82-8, è caratterizzata dalla sua struttura centrale di ossazolidinone, che è un composto eterociclico a cinque membri contenente sia ossigeno che azoto. Questo composto presenta un gruppo idrossimetil e un moiety fenilico fluorurato, che contribuiscono alla sua potenziale attività biologica. La presenza dell'anello di morfolina suggerisce che potrebbe mostrare interazioni specifiche con bersagli biologici, migliorando possibilmente le sue proprietà farmacologiche. La stereochimica indicata dalla designazione (5R) implica che il composto ha un'organizzazione tridimensionale specifica, che può influenzare significativamente la sua reattività e interazione con i sistemi biologici. In generale, questo composto è di interesse nella chimica medicinale, in particolare nello sviluppo di antibiotici e altri agenti terapeutici, grazie alle sue caratteristiche strutturali uniche e alla potenziale efficacia contro vari patogeni. Ulteriori studi sarebbero necessari per chiarire il suo profilo biologico completo e le applicazioni.

Formula: C₁₄H₁₇FN₂O₄

InChI: InChI=1/C14H17FN2O4/c15-12-7-10(17-8-11(9-18)21-14(17)19)1-2-13(12)16-3-5-20-6-4-16/h1-2,7,11,18H,3-6,8-9H2/t11-/m1/s1

SMILES: c1cc(c(cc1N1C[C@H](CO)OC1=O)F)N1CCOCC1

Sinonimi:

• Linezolid Intermediate
• (R)-3-(3-Fluoro-4-Morpholinophenyl)-5-(Hydroxymethyl)Oxazolidin-2-One
• R-N-(3-Fluoro-4-Morpholinylphenyl)-2-Oxo-5-Oxazolidinylmethanol
• (5R)-3-[3-Fluoro-4-(4-Morpholinyl)Phenyl]-5-(Hydroxymethyl)-2-Oxazolidinone
• 2-Oxazolidinone, 3-[3-Fluoro-4-(4-Morpholinyl)Phenyl]-5-(Hydroxymethyl)-, (5R)-
• 3-(3-Fluoro-4-(4-Morpholinyl)Phenyl)-5-Hydroxymethyl-(5R)-2-Oxazolidione
• 2-Oxazolidinone,3-[3-Fluoro-4-(4-Morpholinyl)Phen
• R)-5-(Hydroxymethyl)-3-(3-Fluoro-4-Morpholinopheny
• (5R)-3-[3-Fluoro-4-(4-Morpholinyl)Phenyl]-5-(Hydroxymethyl)-2-Oxazolindinone
• (R)-[N-3-(3-Fluoro-4-Morpholinylphenyl)-2-Oxo-5-Oxazolidinyl]Methanol
• (5R)-3-[3-Fluoro-4-(Morpholin-4-Yl)Phenyl]-5-(Hydroxymethyl)-1,3-Oxazolidin-2-One
• (R)-(3-(3-Flouro-4-Morpholinophenyl)-2-Oxo-5-Oxazolidinyl)Methyl
• (R)-N-[[3-(3-Fluoro-4-Morpholinyl)Phenyl]-2-Oxo-5-Oxazolidinyl]Methanol

(5R)-3-(3-Fluoro-4-morpholinophenyl)-5-(hydroxymethyl)oxazolidin-2-one

CAS: 168828-82-8

Formula: C₁₄H₁₇FN₂O₄

Purezza: 98%

Colore e forma: Solid

Peso molecolare: 296.2942

Ref: IN-DA0032F0

Linezolid Impurity 46

CAS: 168828-82-8

Formula: C₁₄H₁₇FN₂O₄

Colore e forma: Off-White Solid

Peso molecolare: 296.30

Ref: 4Z-L-077

PNU-100440, 10mM (in DMSO)

CAS: 168828-82-8

PNU-100440, 10mM (in DMSO)

Purezza: ≥98%

Peso molecolare: 296.29g/mol

Ref: 54-BUP19965

(5R)-3-(3-Fluoro-4-(4-Morpholinyl)Phenyl)-5-Hydroxymethyl-2-Oxazolidione

CAS: 168828-82-8

(5R)-3-(3-Fluoro-4-(4-Morpholinyl)Phenyl)-5-Hydroxymethyl-2-Oxazolidione

Purezza: 98%

Peso molecolare: 296.29g/mol

Ref: 54-PC109255

PNU-100440

CAS: 168828-82-8

PNU-100440

Purezza: ≥98%

Peso molecolare: 296.29g/mol

Ref: 54-BUP10634

(5R)-3-(3-Fluoro-4-morpholinophenyl)-5-(hydroxymethyl)oxazolidin-2-one

Prodotto controllato

CAS: 168828-82-8

Formula: C₁₄H₁₇FN₂O₄

Colore e forma: Neat

Peso molecolare: 296.30

Ref: 86-MM3300.05

PNU-100440

CAS: 168828-82-8

PNU-100440 is a biologically active compound. It is an intermediate in the synthesis of linezolid dimers, an impurity of the antibacterial agent Linezolid.

Formula: C₁₄H₁₇FN₂O₄

Purezza: 99.09%

Colore e forma: Solid

Peso molecolare: 296.29

Ref: TM-T19645

[(R)-3-(3-Fluoro-4-morpholinophenyl)-2-oxo-5-oxazolidinyl]methanol

Prodotto controllato

CAS: 168828-82-8

Applications [(R)-3-(3-Fluoro-4-morpholinophenyl)-2-oxo-5-oxazolidinyl]methanol is an intermediate in the synthesis of Linezolid Dimer (L466520), an impurity of the antibacterial agent Linezolid (L466500).
References Xu, Heteroatom, Chem., 19, 316 (2008); Wang, J.W., et al.: Lett. Org. Chem., 5, 336 (2008);

Formula: C₁₄H₁₇FN₂O₄

Colore e forma: Light Red

Peso molecolare: 296.30

Ref: TR-F594975

(R)-3-(3-Fluoro-4-(4-morpholinyl)phenyl)-5-(hydroxymethyl)oxazolidin-2-one

CAS: 168828-82-8

(R)-3-(3-Fluoro-4-(4-morpholinyl)phenyl)-5-(hydroxymethyl)oxazolidin-2-one (FPH) is a synthetic drug product that is used as an impurity standard in the synthesis of pharmaceuticals. It is also used in metabolism studies and research and development. FPH has been shown to be a metabolite of the drug product, 3-(3-fluoro-4-(4-morpholinyl)phenyl)-5-(hydroxymethyl)oxazolidin-2-one, which is classified as an API impurity for pharmacopoeia purposes. FPH has a molecular formula of C11H14FO2N2O and a molecular weight of 222.26 g/mol. The CAS number for FPH is 168828-82-8.

Formula: C₁₄H₁₇FN₂O₄

Purezza: Min. 98 Area-%

Colore e forma: Powder

Peso molecolare: 296.29 g/mol

Ref: 3D-IF58045

(R)-3-(3-Fluoro-4-morpholinophenyl)-5-(hydroxymethyl)oxazolidin-2-one

CAS: 168828-82-8

Formula: C₁₄H₁₇FN₂O₄

Purezza: 98%

Colore e forma: Solid

Peso molecolare: 296.298

Ref: 10-F091470

Linezolid Hydroxymethyl Impurity

CAS: 168828-82-8

Formula: C₁₄H₁₇FN₂O₄

Peso molecolare: 296.29

Ref: ST-EA-CP-L40006