CAS 17090-79-8

Monensina

Descrizione:

Monensina è un antibiotico ionoforo polietere prodotto principalmente dalla fermentazione del batterio *Streptomyces cinnamonensis*. È caratterizzato dalla sua capacità di trasportare ioni di sodio attraverso le membrane lipidiche, il che interrompe l'equilibrio ionico cellulare e influisce su vari processi biologici. Monensina è una polvere cristallina bianca a bianco sporco che è solubile in solventi organici come metanolo ed etanolo, ma ha una solubilità limitata in acqua. La sua formula molecolare è C36H61NaO11 e presenta una struttura complessa con più anelli di etere ciclici. Monensina è ampiamente utilizzato in medicina veterinaria, in particolare nel bestiame, per migliorare l'efficienza alimentare e prevenire la coccidiosi, una malattia parassitaria. Inoltre, è stato studiato per le sue potenziali applicazioni in medicina umana, incluso il trattamento del cancro e come agente antivirale. Tuttavia, il suo uso deve essere gestito con attenzione a causa della potenziale tossicità e dello sviluppo di resistenza negli organismi bersaglio. In generale, Monensina è un composto significativo sia in contesti agricoli che farmaceutici.

Formula: C₃₆H₆₁NaO₁₁

InChI: InChI=1/C37H64O10.Na/c1-11-35(32-21(4)18-27(43-32)29-20(3)17-22(5)37(41,12-2)46-29)14-13-28(44-35)34(9)15-16-36(47-34)19-26(38)23(6)31(45-36)24(7)30(42-10)25(8)33(39)40;/h20-32,38,41H,11-19H2,1-10H3,(H,39,40);/q;+1/p-1/t20-,21-,22+,23+,24+,25-,26-,27+,28+,29?,30+,31-,32?,34-,35-,36?,37-;/m0./s1

InChI key: InChIKey=GAOZTHIDHYLHMS-KEOBGNEYSA-N

SMILES: C[C@@]1(O[C@]2(O[C@]([C@H]([C@H]([C@@H](C(O)=O)C)OC)C)([C@H](C)[C@@H](O)C2)[H])CC1)[C@@]3(O[C@@](CC)(CC3)[C@@]4(O[C@](C[C@@H]4C)([C@]5(O[C@](CO)(O)[C@H](C)C[C@@H]5C)[H])[H])[H])[H]

Sinonimi:

• 1,6-Dioxaspiro[4.5]decane, monensin deriv.
• 1,6-Dioxaspiro[4.5]decane-7-butyric acid, 2-[5-ethyltetrahydro-5-[tetrahydro-3-methyl-5-[tetrahydro-6-hydroxy-6-(hydroxymethyl)-3,5-dimethyl-2H-pyran-2-yl]-2-furyl]-2-furyl]-9-hydroxy-β-methoxy-α,γ,2,8-tetramethyl-
• A 3823A
• Elancoban
• Monelan
• Monensic acid
• Monensin A
• Rumensin 90
• Rumensin CRC
• Stereoisomer of 2-[2-ethyloctahydro-3'-methyl-5'-[tetrahydro-6-hydroxy-6-(hydroxymethyl)-3,5-dimethyl-2H-pyran-2-yl][2,2'-bifuran]-5-yl]-9-hydroxy-β-methoxy-α,γ,2,8-tetramethyl-1,6-dioxaspiro[4.5]decane-7-butanoic acid
• Monensin
• (2R,3S,4R)-4-[(2R,5R,7S,8R,9S)-2-{(2S,2'S,3'R,5R,5'S)-2-ethyl-5'-[(2S,3S,5R,6R)-6-hydroxy-6-(hydroxymethyl)-3,5-dimethyltetrahydro-2H-pyran-2-yl]-3'-methyloctahydro-2,2'-bifuran-5-yl}-9-hydroxy-2,8-dimethyl-1,6-dioxaspiro[4.5]dec-7-yl]-3-methoxy-2-methylpentanoic acid
• (2S,3R,4S)-4-[(2S,5R,7S,8R,9S)-2-{(2S,2'R,3'S,5R,5'R)-2-ethyl-5'-[(2S,3S,5R,6R)-6-hydroxy-6-(hydroxymethyl)-3,5-dimethyltetrahydro-2H-pyran-2-yl]-3'-methyloctahydro-2,2'-bifuran-5-yl}-9-hydroxy-2,8-dimethyl-1,6-dioxaspiro[4.5]dec-7-yl]-3-methoxy-2-methylpentanoic acid
• sodium (2S,3R,4R)-4-[(2S,7S,8R,9S)-2-[(2R,5S)-5-ethyl-5-[(3S,5R)-5-[(3S,5R,6S)-6-ethyl-6-hydroxy-3,5-dimethyl-tetrahydropyran-2-yl]-3-methyl-tetrahydrofuran-2-yl]tetrahydrofuran-2-yl]-9-hydroxy-2,8-dimethyl-1,6-dioxaspiro[4.5]decan-7-yl]-3-methoxy-2-methyl-pentanoate
• 4-(2-{2-Ethyl-5'-[6-hydroxy-6-(hydroxymethyl)-3,5-dimethyltetrahydro-2H-pyran-2-yl]-3'-methyloctahydro-2,2'-bifuran-5-yl}-9-hydroxy-2,8-dimethyl-1,6-dioxaspiro[4.5]dec-7-yl)-3-methoxy-2-methylpentanoate
• 2-(5-ethyltetrahydro-5-(tetrahydro-3-6-dioxaspiro(4.5)decane-7-butyricacid
• 1,6-dioxaspiro[4.5]decane-7-butanoato, 2-[2-ethyloctahydro-3'-methyl-5'-[tetrahydro-6-hydroxy-6-(hydroxymethyl)-3,5-dimethyl-2H-pyran-2-yl][2,2'-bifuran]-5-yl]-9-hydroxy-beta-methoxy-alpha,gamma,2,8-tetramethyl-, ion(1-)
• 2-[5-Ethyltetrahydro-5-[tetrahydro-3-methyl-5-[tetrahydro-6-hydroxy-6-(hydroxymethyl)-3,5-dimethyl-2H-pyran-2-yl]-2-furyl]-2-furyl]-9-hydroxy-beta-methoxy-alpha,gamma,2,8-tetramethyl-1,6-dioxaspiro[4.5]decane-7-butyric acid
• MONENSIN(PURE)
• monensicacid
• Monensine sodium
• MONENSIN SODIUM
• MONENSIN SODIUM SALT
• gamma,2,8-tetramethyl--furyl)-2-furyl)-9-hydroxy-beta-methoxy-alph
• 2-[5-Ethyltetrahydro-5-[tetrahydro-3-methyl-5-[tetrahydro-6-hydroxy-6-(hydroxymethyl)-3,5-dimethyl-2H-pyran-2-yl]-2-furyl]-2-furyl]-9-hydroxy--methoxy-a,,2,8-tetramethyl-1,6-dioxaspiro[4.5]decane-7-butyric Acid
• a3823a
• 4-[3-[5-ETHYL-5-[5-[6-HYDROXY-6-(HYDROXYMETHYL)-3,5-DIMETHYL-TETRAHYDROPYRAN-2-YL]-3-METHYL-TETRAHYDROFURAN-2-YL]-TETRAHYDROFURAN-2-YL]-9-HYDROXY-3,8-DIMETHYL-4,6-DIOXASPIRO[4.5]DEC-7-YL]-3-METHOXY-2-METHYL-PENTANOATE
• MONENSINSODIUMSALT(30%)
• MONENSIN A SODIUM SALT
• MONENSIN NA
• Romensin

Monensin

CAS: 17090-79-8

Formula: C₃₆H₆₂O₁₁

Peso molecolare: 670.87

Ref: 7W-GP7543

Monensin

CAS: 17090-79-8

Monensin, from Streptomyces cinnamonensis, inhibits Wnt/β-catenin. Potential anticancer agent.

Formula: C₃₆H₆₂O₁₁

Purezza: 98%

Colore e forma: Crystals White Or Off-White Crystals

Peso molecolare: 670.87

Ref: TM-T1033L

Monensin

CAS: 17090-79-8

Monensin is a polyether ionophore antibiotic, which is derived from the fermentation of the bacterium *Streptomyces cinnamonensis*. It operates by disrupting ion transport across biological membranes, primarily by facilitating the exchange of sodium and potassium ions. This ionophore action alters the osmotic balance in target cells, leading to their destabilization and death, particularly in Gram-positive bacteria and certain protozoa.

Formula: C₃₆H₆₂O₁₁

Purezza: Min. 95%

Peso molecolare: 670.87 g/mol

Ref: 3D-FM31903