CAS 171500-79-1

5,31-Dicloro-38-de(metossicarbonil)-7-desmetil-19-desossi-56-O-[2-desossi-2-(10-metilundecanamido)-β-Dglucopiranosil]-38-[N-[3-(dimetilamino)-propil]carbamoil]-42-O-α-D-manopiranosil-N15-metilristomicina A aglicone

Descrizione:

5,31-Dicloro-38-de(metossicarbonile)-7-desmetil-19-desossi-56-O-[2-desossi-2-(10-metilundecanamido)-β-D-glucopiranosil]-38-[N-[3-(dimetilamino)-propil]carbamoile]-42-O-α-D-mannopiranosil-N15-metilristomicina A aglicone, con numero CAS 171500-79-1, è un composto organico complesso caratterizzato dalla sua struttura intricata, che include più gruppi funzionali e sostituenti. Questa sostanza presenta gruppi dicloro e carbamoile, indicando potenziale reattività e attività biologica. La presenza di unità zuccherine suggerisce che potrebbe avere proprietà glicosidiche, il che potrebbe influenzare la sua solubilità e interazione con i sistemi biologici. Il composto è probabile che mostri proprietà antimicrobiche, poiché è correlato alla ristomicina, un antibiotico noto. La sua complessità strutturale potrebbe anche contribuire al suo profilo farmacologico, inclusi potenziali effetti sulle membrane cellulari o sull'attività enzimatica. In generale, questo composto rappresenta un'area significativa di interesse nella chimica medicinale, in particolare nello sviluppo di nuovi agenti terapeutici.

Formula: Unspecified

InChI: InChI=1S/C88H100Cl2N10O28/c1-38(2)13-10-8-6-7-9-11-14-61(106)94-70-73(109)75(111)78(86(120)121)128-87(70)127-77-58-31-43-32-59(77)124-55-24-19-42(29-50(55)89)71(107)69-85(119)98-67(80(114)92-25-12-26-100(4)5)48-33-44(102)34-57(125-88-76(112)74(110)72(108)60(37-101)126-88)62(48)47-28-40(17-22-52(47)103)65(82(116)99-69)95-83(117)66(43)96-84(118)68-49-35-46(36-54(105)63(49)90)123-56-30-41(18-23-53(56)104)64(91-3)81(115)93-51(79(113)97-68)27-39-15-20-45(122-58)21-16-39/h15-24,28-36,38,51,60,64-76,78,87-88,91,101-105,107-112H,6-14,25-27,37H2,1-5H3,(H,92,114)(H,93,115)(H,94,106)(H,95,117)(H,96,118)(H,97,113)(H,98,119)(H,99,116)(H,120,121)/t51-,60-,64-,65-,66-,67+,68+,69+,70-,71-,72-,73-,74+,75+,76+,78+,87-,88+/m1/s1

InChI key: InChIKey=KGPGQDLTDHGEGT-SZUNQUCBSA-N

SMILES: O(C1=C2C([C@@H](C(NCCCN(C)C)=O)NC(=O)[C@@]3([C@H](O)C=4C=C(Cl)C(=CC4)OC=5C=C6[C@](C(=O)N[C@](C=7C=C2C(O)=CC7)(C(=O)N3)[H])(NC(=O)[C@@]8(C=9C=C(OC=%10C=C([C@@H](NC)C(=O)N[C@@](C(=O)N8)(CC=%11C=CC(OC(=C6)C5O[C@H]%12[C@H](NC(CCCCCCCCC(C)C)=O)[C@@H](O)[C@H](O)[C@@H](C(O)=O)O%12)=CC%11)[H])C=CC%10O)C=C(O)C9Cl)[H])[H])[H])=CC(O)=C1)[C@H]%13O[C@H](CO)[C@@H](O)[C@H](O)[C@@H]%13O

Sinonimi:

• 5,31-Dichloro-38-de(methoxycarbonyl)-7-demethyl-19-deoxy-56-O-[2-deoxy-2-[(10-methyl-1-oxoundecyl)amino]-β-<span class="text-smallcaps">D</smallcap>-glucopyranuronosyl]-38-[[[3-(dimethylamino)propyl]amino]carbonyl]-42-O-α-<smallcap>D</span>-mannopyranosyl-N¹⁵-methylristomycin A aglycone
• A-A 1
• B 7011
• Bi-397
• Dalbavancin
• Dalbavancin B₀
• Dalvance
• Mdl 63397
• Ristomycin A aglycone, 5,31-dichloro-38-de(methoxycarbonyl)-7-demethyl-19-deoxy-56-O-[2-deoxy-2-[(10-methyl-1-oxoundecyl)amino]-β-<span class="text-smallcaps">D</smallcap>-glucopyranuronosyl]-38-[[[3-(dimethylamino)propyl]amino]carbonyl]-42-O-α-<smallcap>D</span>-mannopyranosyl-N¹⁵-methyl-
• V-Glycopeptide
• Ver 001
• 5,31-Dichloro-38-de(methoxycarbonyl)-7-demethyl-19-deoxy-56-O-[2-deoxy-2-[(10-methyl-1-oxoundecyl)amino]-β-D-glucopyranuronosyl]-38-[[[3-(dimethylamino)propyl]amino]carbonyl]-42-O-α-D-mannopyranosyl-N15-methylristomycin A aglycone
• Dalbavancin(BI 397, MDL 63397)

Ristomycin A aglycone,5,31-dichloro-38-de(methoxycarbonyl)-7-demethyl-19-deoxy-56-O-[2-deoxy-2-[(10-methyl-1-oxoundecyl)amino]-b-D-glucopyranuronosyl]-38-[[[3-(dimethylamino)propyl]amino]carbonyl]-42-O-a-D-mannopyranosyl-N15-methyl-

CAS: 171500-79-1

Formula: C₈₈H₁₀₀Cl₂N₁₀O₂₈

Purezza: 98%

Colore e forma: Solid

Peso molecolare: 1816.6918

Ref: IN-DA00ABNL

Dalbavancin

CAS: 171500-79-1

Formula: C₈₈H₁₀₀Cl₂N₁₀O₂₈

Peso molecolare: 1816.71

Ref: 4Z-D-176013

Dalbavancin

CAS: 171500-79-1

Dalbavancin (BI-397) is a lipoglycopeptide antibiotic effective against Gram-positive pathogens, MRSA, MRSE, with MIC90s of 0.06-0.25 μg/mL.

Formula: C₈₈H₁₀₀Cl₂N₁₀O₂₈

Purezza: 99.09%

Colore e forma: Solid

Peso molecolare: 1816.71

Ref: TM-T21358

Dalbavancin Hydrochloride

Prodotto controllato

CAS: 171500-79-1

Applications Dalbavancin is a second-generation lipoglycopeptide antibiotic. It is a semisynthetic lipoglycopeptide that was designed to improve upon the natural glycopeptides currently available, vancomycin and teicoplanin.
References Scheinfeld, N.: Derm. Online J., 12 (2006); Chen, A., et al.: Int. J. Clin. Prac., 61, 853 (2007)

Formula: C₈₈H₁₀₀Cl₂N₁₀O₂₈·HCl

Colore e forma: Neat

Peso molecolare: 1816.69

Ref: TR-D110000

Dalbavancin

CAS: 171500-79-1

Dalbavancin is a lipoglycopeptide antibiotic with action against gram-positive bacteria, including MRSA and is used for treating acute bacterial skin and skin structure infections.

Formula: C₈₈H₁₀₀Cl₂N₁₀O₂₈

Purezza: Min. 95%

Colore e forma: Powder

Peso molecolare: 1,816.69 g/mol

Ref: 3D-AD30090

Dalbavancin

CAS: 171500-79-1

Formula: C₈₈H₁₀₀Cl₂N₁₀O₂₈

Peso molecolare: 1816.7

Ref: ST-EA-CP-D132000