CAS 171596-29-5

Tadalafil

Descrizione:

Tadalafil è un inibitore della fosfodiesterasi di tipo 5 (PDE5) utilizzato principalmente per il trattamento della disfunzione erettile e dell'ipertensione arteriosa polmonare. È caratterizzato dalla sua capacità di migliorare il flusso sanguigno rilassando i vasi sanguigni nel pene, facilitando un'erezione in risposta alla stimolazione sessuale. Tadalafil ha una lunga emivita, che consente effetti prolungati, che possono durare fino a 36 ore, guadagnandosi il soprannome di "pillola del weekend". La struttura chimica di Tadalafil include una struttura biciclica con un anello di pirimidina, contribuendo alle sue proprietà farmacologiche. Viene tipicamente somministrato per via orale ed è disponibile in diverse dosi. Tadalafil è generalmente ben tollerato, ma può causare effetti collaterali come mal di testa, arrossamento e dispepsia. È importante notare che Tadalafil non deve essere usato in concomitanza con nitrati a causa del rischio di ipotensione severa. In generale, Tadalafil rappresenta un significativo progresso nella gestione della disfunzione erettile e delle condizioni correlate, fornendo ai pazienti un'opzione terapeutica affidabile.

Formula: C₂₂H₁₉N₃O₄

InChI: InChI=1S/C22H19N3O4/c1-24-10-19(26)25-16(22(24)27)9-14-13-4-2-3-5-15(13)23-20(14)21(25)12-6-7-17-18(8-12)29-11-28-17/h2-8,16,21,23H,9-11H2,1H3/t16-,21-/m1/s1

InChI key: InChIKey=WOXKDUGGOYFFRN-IIBYNOLFSA-N

SMILES: O=C1N2[C@@H](C3=C(C=4C(N3)=CC=CC4)C[C@@]2(C(=O)N(C)C1)[H])C=5C=C6C(=CC5)OCO6

Sinonimi:

• (6R,12Ar)-6-(1,3-Benzodioxol-5-Yl)-2,3,6,7,12,12A-Hexahydro-2-Methyl-Pyrazino[1',2':1,6]Pyrido[3,4-B]Indole-1,4-Dione
• (6R,12aR)-2,3,6,7,12,12a-hexahydro-2-methyl-6-(3,4-methylenedioxyphenyl)pyrazino[1′,2′:1,6]pyrido[3,4-b]indole-1,4-dione
• (6R,12aR)-6-(1,3-Benzodioxol-5-yl)-2,3,6,7,12,12a-hexahydro-2-methylpyrazino[1′,2′:1,6]pyrido[3,4-b]indole-1,4-dione
• (6R,12aR)-6-(1,3-benzodioxol-5-yl)-2-methyl-2,3,6,7,12,12a-hexahydropyrazino[1',2':1,6]pyrido[3,4-b]indole-1,4-dione
• (6R,12aR)-6-(1,3-benzodioxol-5-yl)-2-methyl-3,4,6,6a,7,11b,12,12a-octahydropyrazino[1',2':1,6]pyrido[3,4-b]indol-1(2H)-one
• Adcirca
• Cialis
• Gf 196960
• Ic-351
• Icos 351
• Lifta
• Pentadafil
• Pyrazino[1′,2′:1,6]pyrido[3,4-b]indole-1,4-dione, 6-(1,3-benzodioxol-5-yl)-2,3,6,7,12,12a-hexahydro-2-methyl-, (6R,12aR)-
• Pyrazino[1′,2′:1,6]pyrido[3,4-b]indole-1,4-dione, 6-(1,3-benzodioxol-5-yl)-2,3,6,7,12,12a-hexahydro-2-methyl-, (6R-trans)-
• Tadalafil Lilly
• Tadanafil
• Tadfil
• Tadora
• Talmanco
• Tardenafil
• Tildenafil
• Uk 336017

Tadalafil

CAS: 171596-29-5

Formula: C₂₂H₁₉N₃O₄

Purezza: >98.0%(T)(HPLC)

Colore e forma: White to Light yellow powder to crystal

Peso molecolare: 389.41

Ref: 3B-T4029

Tadalafil 1.0 mg/ml in Acetonitrile

CAS: 171596-29-5

Colore e forma: Single Solution

Ref: 61-AMP0806.00-11

TADALAFIL CRS

CAS: 171596-29-5

TADALAFIL CRS

Formula: C₂₂H₁₉N₃O₄

Peso molecolare: 389.404

Ref: 41-Y0001417

Tadalafil

CAS: 171596-29-5

Nucleic acids and their salts, whether or not chemically defined; other heterocyclic compounds, nesoi

Formula: C₂₂H₁₉N₃O₄

Colore e forma: White Off-White Powder

Peso molecolare: 389.13756

Ref: 45-1642879

(6R,12aR)-6-(Benzo[d][1,3]dioxol-5-yl)-2-methyl-2,3,12,12a-tetrahydropyrazino[1',2':1,6]pyrido[3,4-b]indole-1,4(6H,7H)-dione

CAS: 171596-29-5

Formula: C₂₂H₁₉N₃O₄

Purezza: 95%

Colore e forma: Solid

Peso molecolare: 389.4040

Ref: IN-DA0037XA

Tadalafil

CAS: 171596-29-5

Tadalafil (IC-351) is a carboline-based compound with vasodilatory activity.

Formula: C₂₂H₁₉N₃O₄

Purezza: 97.03%

Colore e forma: Off-White Cyrstalline Solid

Peso molecolare: 389.40

Ref: TM-T1398

Cialis

CAS: 171596-29-5

Cialis

Purezza: 99%

Peso molecolare: 389.4g/mol

Ref: 54-OR1026996

Tadalafil

CAS: 171596-29-5

Formula: C₂₂H₁₉N₃O₄

Purezza: ≥ 98%

Colore e forma: White to light-yellow powder

Peso molecolare: 389.40

Ref: 7W-GP0380

Tadalafil

CAS: 171596-29-5

Formula: C₂₂H₁₉N₃O₄

Colore e forma: White To Off-White Solid

Peso molecolare: 389.41

Ref: 4Z-T-103

Tadalafil

CAS: 171596-29-5

Tadalafil

Purezza: ≥95%

Peso molecolare: 389.4g/mol

Ref: 54-BUP17162

Tadalafil

CAS: 171596-29-5

Colore e forma: Neat

Ref: 61-FOR0806.00

Tadalafil

CAS: 171596-29-5

Formula: C₂₂H₁₉N₃O₄

Colore e forma: Neat

Peso molecolare: 389.40

Ref: 04-C17133000

Tadalafil

CAS: 171596-29-5

Colore e forma: Neat

Ref: 86-MM0806.00

Tadalafil

Prodotto controllato

CAS: 171596-29-5

Stability Unstable in Methanol
Applications Tadalafil is used for the treatment of erectile dysfunction. A phosphodiesterase 5 inhibitor.
References Carrier, S., et al.: Can. J. Urol., 10(1), 12 (2003); Doggrell, S.A., et al.: Expert Opin. Pharmacother., 6, 75 (2005); Forgue, S.T., et al.: Br. J. Clin. Pharmacol., 61, 280 (2005);

Formula: C₂₂H₁₉N₃O₄

Colore e forma: White To Off-White

Peso molecolare: 389.40

Ref: TR-T004500

Tadalafil

CAS: 171596-29-5

Tadalafil is a phosphodiesterase type 5 inhibitor that is used to treat erectile dysfunction by increasing blood flow to the penis. It is an oral drug that blocks the enzyme phosphodiesterase type 5 (PDE5) and increases the levels of cyclic guanosine monophosphate (cGMP) in smooth muscle cells, leading to vasodilation and increased blood flow. Tadalafil has been shown to be effective in men with pulmonary hypertension and primary pulmonary hypertension. Tadalafil also has a side-effect profile similar to other PDE5 inhibitors, including headache, dizziness, nausea, nasal congestion or runny nose, indigestion, diarrhea or constipation, back pain and muscle pain. This drug also interacts with drugs that can cause serious adverse effects if taken with PDE5 inhibitors. Tadalafil is not active against bacteria; therefore it cannot be used for the treatment of bacterial infections such as tuberculosis.

Formula: C₂₂H₁₉N₃O₄

Purezza: (Hplc) Min. 98%

Colore e forma: White Powder

Peso molecolare: 389.4 g/mol

Ref: 3D-FB02802

Tadalafil - Bio-X ™

CAS: 171596-29-5

Tadalafil is a phosphodiesterase (PDE) inhibitor used to treat erectile dysfunction. It works by inhibiting the enzyme PDE, which is responsible for breaking down cGMP, a molecule that relaxes smooth muscle cells in the penis and allows for increased blood flow. Tadalafil has an ability to also act as a channel inhibitor and nerve growth factor inhibitor. Additionally, it is said to aid with pulmonary arterial hypertension by relaxing the blood vessels in the lungs to allow blood to flow more easily.

Formula: C₂₂H₁₉N₃O₄

Purezza: Min. 95%

Colore e forma: Powder

Peso molecolare: 389.4 g/mol

Ref: 3D-BT164435

Tadalafil-13C2,d3

Prodotto controllato

CAS: 171596-29-5

Applications Tadalafil-13C2,d3 is labelled Tadalafil (T004500) which is used for the treatment of erectile dysfunction. It is a phosphodiesterase 5 inhibitor.
References Carrier, S., et al.: Can. J. Urol., 10(1), 12 (2003), Doggrell, S.A., et al.: Expert Opin. Pharmacother., 6, 75 (2005), Forgue, S.T., et al.: Br. J. Clin. Pharmacol., 61, 280 (2005)

Formula: C₂₀₁₃C₂H₁₆D₃N₃O₄

Colore e forma: White Powder

Peso molecolare: 394.41

Ref: TR-T004502

2-Triethylmethyl Tadalafil

Prodotto controllato

CAS: 171596-29-5

Formula: C₂₇H₂₉N₃O₄

Colore e forma: Neat

Peso molecolare: 459.537

Ref: TR-T776663