CAS 171599-83-0

citrato di sildenafil

Descrizione:

citrato di sildenafil è un composto farmaceutico conosciuto principalmente per il suo uso nel trattamento della disfunzione erettile e dell'ipertensione arteriosa polmonare. Funziona come un inibitore selettivo della fosfodiesterasi di tipo 5 (PDE5), che potenzia gli effetti dell'ossido nitrico aumentando i livelli di monofosfato di guanosina ciclico (cGMP) nel corpo cavernoso, portando a vasodilatazione e miglioramento del flusso sanguigno. La sostanza appare come una polvere cristallina bianca o bianco sporco ed è solubile in acqua, rendendola adatta per somministrazione orale. La sua formula molecolare è C22H30N6O4S e ha un peso molecolare di circa 474,6 g/mol. citrato di sildenafil viene tipicamente somministrato in forma di compresse, con varie dosi disponibili, ed è noto per avere un inizio d'azione relativamente rapido. Gli effetti collaterali comuni possono includere mal di testa, arrossamento e dispepsia, mentre le controindicazioni includono l'uso di nitrati e alcune condizioni cardiovascolari. In generale, citrato di sildenafil ha avuto un impatto significativo nel trattamento della disfunzione erettile dalla sua introduzione, migliorando la qualità della vita di molte persone.

Formula: C₂₈H₃₈N₆O₁₁S

InChI: InChI=1/C21H28N6O4S/c1-4-6-16-18-19(25-24-16)21(28)23-20(22-18)15-13-14(7-8-17(15)31-5-2)32(29,30)27-11-9-26(3)10-12-27/h7-8,13H,4-6,9-12H2,1-3H3,(H,24,25)(H,22,23,28)

InChI key: InChIKey=DEIYFTQMQPDXOT-UHFFFAOYSA-N

SMILES: O(CC)C1=C(C=C(S(=O)(=O)N2CCN(C)CC2)C=C1)C=3NC4=C(C(=O)N3)N(C)N=C4CCC.C(CC(O)=O)(CC(O)=O)(C(O)=O)O

Sinonimi:

• 1-[[3-(6,7-Dihydro-1-methyl-7-oxo-3-propyl-1H-pyrazolo[4,3-d]pyrimidin-5-yl)-4-ethoxyphenyl]sulfonyl]-4-methylpiperazine, 2-hydroxy-1,2,3-propanetricarboxylate (1:1)
• 5-[2-Ethoxy-5-(4-methylpiperazin-1-yl-sulphonyl)phenyl]-1-methyl-3-n-propyl-1,6-dihydro-7H-pyrazol[4,3d]pyrimidin-7-one citrate
• 5-{2-ethoxy-5-[(4-methylpiperazin-1-yl)sulfonyl]phenyl}-1-methyl-3-propyl-1,4-dihydro-7H-pyrazolo[4,3-d]pyrimidin-7-one 2-hydroxypropane-1,2,3-tricarboxylate (1:1)
• 5-{2-ethoxy-5-[(4-methylpiperazin-1-yl)sulfonyl]phenyl}-3-propyl-2,4-dihydro-7H-pyrazolo[4,3-d]pyrimidin-7-one
• 7H-Pyrazolo[4,3-d]pyrimidin-7-one, 5-[2-ethoxy-5-[(4-methyl-1-piperazinyl)sulfonyl]phenyl]-1,6-dihydro-1-methyl-3-propyl-, 2-hydroxy-1,2,3-propanetricarboxylate (1:1)
• Actra-R_x
• Alisiga
• Apodefil
• Caverta 100
• Edegra
• Granpidam
• Kamagra
• Maxifort
• Mysildecard
• Niagra Actra-R_x
• Penegra
• Piperazine, 1-[[3-(4,7-dihydro-1-methyl-7-oxo-3-propyl-1H-pyrazolo[4,3-d]pyrimidin-5-yl)-4-ethoxyphenyl]sulfonyl]-4-methyl-, 2-hydroxy-1,2,3-propanetricarboxylate (1:1)
• Sidenafil citrate
• Sildegra
• Sildigra
• Siligra
• Sollevare
• Tonafil
• Uk 92480
• Uk 92480-10
• Vega (pharmaceutical)
• Viagra
• Vigrex
• Zenegra
• Sildenafil citrate
• 1-[[3-(4,7-Dihydro-1-methyl-7-oxo-3-propyl-1H-pyrazolo[4,3-d]pyrimidin-5-yl)-4-ethoxyphenyl]sulfonyl]-4-methylpiperazine, Citrate
• SILDENAFIL CITRATE(RG)
• uk92480-10
• 1-[[3-(6,7-dihydro-1-methyl-7-oxo-3-propyl-1h-pyrazolo[4,3-d]pyrimidin-5-yl)-4-ethoxyphenyl]sulfonyl]-4-methylpiperazine citrate
• SildenafilCitrate/SildenafilBaseC28H38N6O11S
• 5(2-ETHOXY-5(4-METHYLPIPERAZINE)SULPHONYLPHENYL)-1
• din-5-yl)-4-ethoxyphenyl)sulfonyl)-4-methyl-,2-hydroxy-1,2,3-propanetricarbo
• piperazine,1-((3-(4,7-dihydro-1-methyl-7-oxo-3-propyl-1h-pyrazolo(4,3-d)pyrimi
• SildenafilBaseC28H38N6O11S
• 1-[[3-(6,7-Dihydro-1-methyl-7-oxo-3-propyl-1H-pyrazolo[4,3-d]pyrimidin-5-yl)-4-ethoxyphenyl]sulfonyl]-4-methylpiperazine citrate
• SILDANAFIL CITRATE (BULK)

Sildenafil Citrate

CAS: 139755-83-2, 171599-83-0

Formula: C₂₂H₃₀N₆O₄S·C₆H₈O₇

Purezza: >98.0%(HPLC)

Colore e forma: White to Almost white powder to crystal

Peso molecolare: 666.70

Ref: 3B-S0986

Sildenafil citrate

CAS: 171599-83-0

Colore e forma: Neat

Ref: LP-SIL-984-CI-10

Sildenafil citrate, 1mg/ml in Methanol (as free base)

CAS: 171599-83-0

Colore e forma: Single Solution

Ref: LP-SIL-984-CI-1LM

Sildenafil citrate

CAS: 171599-83-0

Colore e forma: Neat

Ref: 61-FOR0254.00

SILDENAFIL FOR PEAK IDENTIFICATION CRS

CAS: 171599-83-0

SILDENAFIL FOR PEAK IDENTIFICATION CRS

Formula: C₂₈H₃₈N₆O₁₁S

Peso molecolare: 666.6999

Ref: 41-Y0001891

SILDENAFIL CITRATE CRS

CAS: 171599-83-0

SILDENAFIL CITRATE CRS

Formula: C₂₈H₃₈N₆O₁₁S

Peso molecolare: 666.6999

Ref: 41-Y0001578

Sildenafil Citrate

CAS: 171599-83-0

Drugs containing a pyrimidine ring (whether or not hydrogenated) or piperazine ring in the structure

Formula: C₂₂H₃₀N₆O₄S·C₆H₈O₇

Colore e forma: White Off-White Crystalline Powder

Peso molecolare: 474.20492

Ref: 45-1612561

Sildenafil citrate

CAS: 171599-83-0

Sildenafil citrate, a PDE5 inhibitor for erectile dysfunction and occasionally pulmonary hypertension.

Formula: C₂₈H₃₈N₆O₁₁S

Purezza: 99.59% - 99.97%

Colore e forma: White Solid

Peso molecolare: 666.70

Ref: TM-T0467

Sildenafil Citrate

CAS: 171599-83-0

Formula: C₂₂H₃₀N₆O₄S·C₆H₈O₇

Colore e forma: White To Off-White Solid

Peso molecolare: 474.58 192.12

Ref: 4Z-S-061

Sildenafil citrate

CAS: 171599-83-0

Sildenafil citrate

Purezza: ≥98%

Peso molecolare: 666.7g/mol

Ref: 54-BUP17834

Sildenafil citrate

CAS: 171599-83-0

Formula: C₂₂H₃₀N₆O₄S·C₆H₈O₇

Purezza: ≥ 99.0% (dried basis)

Colore e forma: White powder

Peso molecolare: 666.70

Ref: 7W-GP3242

Sildenafil citrate

CAS: 171599-83-0

Formula: C₂₂H₃₀N₆O₄S·C₆H₈O₇

Colore e forma: Neat

Peso molecolare: 666.70

Ref: 04-C16946500

Sildenafil Citrate

CAS: 171599-83-0

Colore e forma: Neat

Ref: 86-MM0254.00

Sildenafil Citrate

Prodotto controllato

CAS: 171599-83-0

Stability Store in Freezer
Applications Sildenafil Citrate is an orally active selective type 5 cGMP phosphodiesterase inhibitor.
References Terrett, N.K., et al.: Bioorg. Med. Chem. Lett., 6, 1819 (1996), Goldstein, I., et al.: N. Engl. J. Med., 338, 1397 (1998),

Formula: C₂₂H₃₀N₆O₄S·C₆H₈O₇

Colore e forma: White To Off-White

Peso molecolare: 666.70

Ref: TR-S435000

Sildenafil Citrate-d3

Prodotto controllato

CAS: 171599-83-0

Formula: C₂₂H₂₇D₃N₆O₄S•(C₆H₈O₇)

Colore e forma: Off-White

Peso molecolare: 669.71

Ref: TR-S435004

Sildenafil citrate

CAS: 171599-83-0

Sildenafil is an inhibitor of phosphodiesterase type-5 (PDE-5). It is used in the treatment of erectile dysfunction. Sildenafil inhibits the enzyme phosphodiesterase type-5, which prevents the conversion of cyclic guanosine monophosphate to cyclic adenosine monophosphate, and this results in relaxation of smooth muscle cells and increased blood flow to the corpus cavernosum. The PDE-5 inhibitors are selective for human PDE-5 and do not inhibit PDEs 1, 2, 3, or 6. The inhibition of PDE-5 by sildenafil is reversible. Sildenafil has been shown to be a potent inhibitor of cyclase activity in vitro. br> The LC/MS/MS method was developed to measure the concentration of sildenafil in human serum. This analytical method provides a linear calibration curve with limits of quant

Formula: C₂₈H₃₈N₆O₁₁S

Purezza: Min. 95%

Colore e forma: White Powder

Peso molecolare: 666.7 g/mol

Ref: 3D-FS27829

Sildenafil citrate - Bio-X ™

CAS: 171599-83-0

A potent selective inhibitor of cGMP-specific phosphodiesterase type 5 (PDE-5), thereby reducing the degradation rate of cGMP. Sildenafil is used to treat erectile dysfunction and pulmonary arterial hypertension.
Sildenafil citrate is part of our Bio-X ™ Range. These products are aimed at life science researchers who need high quality ready to use products for assay development, screening or other R&D work. With a solubility datasheet and convenient vials, all of our Bio-X ™ products are in stock across our global warehouses for rapid delivery and ease of use.

Formula: C₂₈H₃₈N₆O₁₁S

Purezza: Min. 95%

Peso molecolare: 666.7 g/mol

Ref: 3D-BS164405