CAS 17162-39-9

Tartarato di fenilefrina

Descrizione:

Tartarato di fenilefrina è un composto farmaceutico utilizzato principalmente come decongestionante e agente midriatico. È il sale tartrato della fenilefrina, che è un agonista adrenergico alfa-1. Questo composto è caratterizzato dalla sua capacità di costringere i vasi sanguigni, portando a una riduzione della congestione nasale e a un aumento della pressione sanguigna. Nella sua forma pura, Tartarato di fenilefrina appare come una polvere cristallina bianca o bianco sporco, solubile in acqua e con un sapore leggermente amaro. La struttura molecolare include un gruppo fenolico, contribuendo alla sua attività farmacologica. Viene comunemente somministrato in varie formulazioni, tra cui compresse orali e soluzioni iniettabili. Il composto è generalmente ben tollerato, anche se può causare effetti collaterali come ipertensione, bradicardia riflessa o irritazione locale nel sito di somministrazione. Grazie alle sue proprietà vasocostrittrici, Tartarato di fenilefrina è spesso utilizzato in contesti clinici per gestire l'ipotensione durante l'anestesia e per trattare la congestione nasale associata a raffreddori o allergie.

Formula: C₁₃H₁₉NO₈

InChI: InChI=1/C9H13NO2.C4H6O6/c1-10-6-9(12)7-3-2-4-8(11)5-7;5-1(3(7)8)2(6)4(9)10/h2-5,9-12H,6H2,1H3;1-2,5-6H,(H,7,8)(H,9,10)/t9-;1-,2+/m0./s1

InChI key: InChIKey=NHKOTKKHHYKARN-NDAAPVSOSA-N

SMILES: [C@@H]([C@H](C(O)=O)O)(C(O)=O)O.[C@@H](CNC)(O)C1=CC(O)=CC=C1

Sinonimi:

• 3-[(1R)-1-hydroxy-2-(methylamino)ethyl]phenol 2,3-dihydroxybutanedioate (salt)
• <span class="text-smallcaps">L</span>-Phenylephedrine bitartrate
• Benzenemethanol, 3-hydroxy-α-[(methylamino)methyl]-, (R)-, [R-(R*,R*)]-2,3-dihydroxybutanedioate (1:1) (salt)
• Benzenemethanol, 3-hydroxy-α-[(methylamino)methyl]-, (αR)-, (2R,3R)-2,3-dihydroxybutanedioate (1:1)
• Benzenemethanol, 3-hydroxy-α-[(methylamino)methyl]-, (αR)-, (2R,3R)-2,3-dihydroxybutanedioate (1:1) (salt)
• Benzyl alcohol, m-hydroxy-α-[(methylamino)methyl]-, (-)-, tartrate (1:1) (salt)
• Phenylephrine bitartrate
• Phenylephrine tartrate
• Phenylephrine hydrogentartrate
• L-Phenylephedrine bitartrate
• (R)-(beta-,3-dihydroxyphenethyl)methylammonium hydrogen [R-(R*,R*)]-tartrate
• BENZENEMETHANOL, 3-HYDROXY-ALPHA-[(METHYLAMINO)METHYL]-, (AR)-, (2R,3R)-2,3-DIHYDROXYBUTANEDIOATE (1:1) (SALT)
• (-)-PHENYLEPHRINE-(+)-HYDROGEN TARTRATE
• (R)-[2-Hydroxy-2-(3-hydroxyphenyl)-ethyl)methylammonium-hydrogen-[R-(R*,R*)]-tartrate
• BENZENEMETHANOL,3-HYDROXY-A-[(METHYLAMINO)METHYL]-,(AR)-,(2R,3R)-2,3-DIHYDROXYBUTANEDIOATE

Phenylephrine Bitartrate

CAS: 17162-39-9

Aromatic amino-alcohol-phenols, aromatic amino-acid-phenols and other aromatic amino compounds with oxygen function

Formula: C₉H₁₃NO₂·C₄H₆O₆

Colore e forma: White Off-White Powder

Peso molecolare: 167.09463

Ref: 45-1532950

(-)-Phenylephrine hydrogentartrate

CAS: 17162-39-9

(-)Phenylephrine is a medication that belongs to the group of drugs called sympathomimetics. This drug is a potent vasoconstrictor that causes blood vessels to narrow and increases blood pressure. (-)Phenylephrine is used in humans as a pharmaceutical dosage for treatment of chronic bronchitis, hay fever, and other allergic reactions. It also has been shown to inhibit guanylate cyclase activity and can be used for the treatment of asthma. (-)Phenylephrine inhibits the action of two enzymes: cyclase and phosphodiesterase. This inhibition leads to an increased level of cAMP, which binds with G protein-coupled receptors in tissues that are rich in smooth muscle cells such as the airways or urinary bladder. The binding of cAMP with these receptors causes an increase in intracellular calcium ion levels, leading to relaxation of smooth muscles and improved breathing or urination.

Formula: C₉H₁₃NO₂·C₄H₆O₆

Purezza: Min. 98 Area-%

Colore e forma: Powder

Peso molecolare: 317.29 g/mol

Ref: 3D-FP33906