CAS 17598-65-1

Deslanoside

Descrizione:

Deslanoside è un glicoside cardiaco, derivato principalmente dalla pianta Digitalis lanata, ed è utilizzato nel trattamento delle condizioni cardiache, in particolare l'insufficienza cardiaca e la fibrillazione atriale. Funziona inibendo la pompa ATPasi sodio-potassio, portando a un aumento delle concentrazioni intracellulari di sodio e calcio, il che migliora la contrattilità cardiaca. Deslanoside è caratterizzato dalla sua capacità di migliorare l'efficienza dell'azione di pompaggio del cuore, esercitando al contempo un effetto cronotropo negativo, che rallenta la frequenza cardiaca. Il composto viene tipicamente somministrato in modo controllato a causa del suo stretto indice terapeutico, il che significa che la differenza tra una dose efficace e una dose tossica è ridotta. Gli effetti collaterali possono includere disturbi gastrointestinali, cambiamenti visivi e aritmie, richiedendo un attento monitoraggio dei livelli sierici. Deslanoside è spesso utilizzato in combinazione con altri farmaci per ottimizzare la funzione cardiaca e gestire i sintomi in modo efficace. La sua farmacocinetica coinvolge assorbimento, distribuzione, metabolismo ed escrezione che possono essere influenzati da vari fattori, comprese le caratteristiche specifiche del paziente e i farmaci concomitanti.

Formula: C₄₇H₇₄O₁₉

InChI: InChI=1/C47H74O19/c1-20-41(64-36-16-30(50)42(21(2)60-36)65-37-17-31(51)43(22(3)61-37)66-44-40(56)39(55)38(54)32(18-48)63-44)29(49)15-35(59-20)62-25-8-10-45(4)24(13-25)6-7-27-28(45)14-33(52)46(5)26(9-11-47(27,46)57)23-12-34(53)58-19-23/h12,20-22,24-33,35-44,48-52,54-57H,6-11,13-19H2,1-5H3/t20-,21-,22-,24-,25+,26-,27-,28+,29+,30+,31+,32-,33-,35+,36+,37+,38-,39+,40-,41-,42-,43-,44+,45+,46+,47+/m1/s1

InChI key: InChIKey=OBATZBGFDSVCJD-LALPQLPRSA-N

SMILES: O[C@@]12[C@@](C)([C@H](CC1)C3=CC(=O)OC3)[C@H](O)C[C@]4([C@]2(CC[C@]5([C@]4(C)CC[C@H](O[C@H]6C[C@H](O)[C@H](O[C@H]7C[C@H](O)[C@H](O[C@H]8C[C@H](O)[C@H](O[C@@H]9O[C@H](CO)[C@@H](O)[C@H](O)[C@H]9O)[C@@H](C)O8)[C@@H](C)O7)[C@@H](C)O6)C5)[H])[H])[H]

Sinonimi:

• (3beta,5beta,12beta)-3-{[beta-D-glucopyranosyl-(1->4)-2,6-dideoxy-beta-D-ribo-hexopyranosyl-(1->4)-2,6-dideoxy-beta-D-ribo-hexopyranosyl-(1->4)-2,6-dideoxy-beta-D-ribo-hexopyranosyl]oxy}-12,14-dihydroxycard-20(22)-enolide
• (3β,5β,12β)-3-[(O-β-<span class="text-smallcaps">D</smallcap>-Glucopyranosyl-(1→4)-O-2,6-dideoxy-β-<smallcap>D</smallcap>-ribo-hexopyranosyl-(1→4)-O-2,6-dideoxy-β-<smallcap>D</smallcap>-ribo-hexopyranosyl-(1→4)-2,6-dideoxy-β-<smallcap>D</span>-ribo-hexopyranosyl)oxy]-12,14-dihydroxycard-20(22)-enolide
• Card-20(22)-enolide, 3-[(O-β-<span class="text-smallcaps">D</smallcap>-glucopyranosyl-(1→4)-O-2,6-dideoxy-β-<smallcap>D</smallcap>-ribo-hexopyranosyl-(1→4)-O-2,6-dideoxy-β-<smallcap>D</smallcap>-ribo-hexopyranosyl-(1→4)-2,6-dideoxy-β-<smallcap>D</span>-ribo-hexopyranosyl)oxy]-12,14-dihydroxy-, (3β,5β,12β)-
• Card-20(22)-enolide, 3-[(O-β-D-glucopyranosyl-(1→4)-O-2,6-dideoxy-β-D-ribo-hexopyranosyl-(1→4)-O-2,6-dideoxy-β-D-ribo-hexopyranosyl-(1→4)-2,6-dideoxy-β-D-ribo-hexopyranosyl)oxy]-12,14-dihydroxy-, (3β,5β,12β)-
• Cedilanid D
• Cedilanidd
• De-O-acetyllanatoside C
• Deacetyl-Lanatoside
• Deacetylanatoside C
• Deacetyllanatoside C
• Desace
• Desacetyllanatoside C
• Desacetyllanatosidec
• Desaci
• Descetyldigilanidec
• Deslanatoside
• Deslanatoside C
• Deslanosid
• Deslanoside C
• Deslanosido
• Deslanosidum
• Lanatoside C, deacetyl-
• Purpurea glycoside C
• Deslanoside
• (3β,5β,12β)-3-[(O-β-D-Glucopyranosyl-(1→4)-O-2,6-dideoxy-β-D-ribo-hexopyranosyl-(1→4)-O-2,6-dideoxy-β-D-ribo-hexopyranosyl-(1→4)-2,6-dideoxy-β-D-ribo-hexopyranosyl)oxy]-12,14-dihydroxycard-20(22)-enolide
• Desacetyl-Lanatosid C
• sediranido
• Lanatoside C, deacetyl-(6CI, 7CI, 8CI)

DESLANOSIDE CRS

CAS: 17598-65-1

DESLANOSIDE CRS

Ref: 41-D0600000

Deslanoside

CAS: 17598-65-1

Other glycosides, natural or reproduced by synthesis, and their salts, ethers, esters and other derivatives

Formula: C₄₇H₇₄O₁₉

Colore e forma: Powder

Peso molecolare: 942.48243

Ref: 45-1173009

Deslanoside

CAS: 17598-65-1

Deslanoside

Purezza: ≥98%

Peso molecolare: 943.08g/mol

Ref: 54-BUP20803

Deslanoside

CAS: 17598-65-1

Deslanoside is a fast-acting cardiac glycoside for heart failure and arrhythmias, blocking Na-K-ATPase to boost sodium and calcium.

Formula: C₄₇H₇₄O₁₉

Purezza: 99.39% - 99.89%

Colore e forma: Solid

Peso molecolare: 943.08

Ref: TM-T8183

Deslanoside RS

CAS: 17598-65-1

Colore e forma: Colorless Or White

Ref: 2K-1085000021

Desacetyllanatoside C

Prodotto controllato

CAS: 17598-65-1

Applications Desacetyllanatoside C is a derivative of Lanatoside C (L173800), glycosides isolated from various species of Digitalis. Cardiotonic.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Novotny, J., et al.: J. Biol. Chem., 258, 14433 (1983), Farr, C., et al.: J. Med. Chem., 45, 3257 (2002), Van Dongen, M., et al.: Drug Discov. Today, 7, 471 (2002),

Formula: C₄₇H₇₄O₁₉

Colore e forma: Neat

Peso molecolare: 943.08

Ref: TR-D288320

Deslanoside

CAS: 17598-65-1

Deslanoside is a cardiac glycoside, which is derived from the leaves of the Digitalis lanata plant. As a member of the cardiac glycoside family, it functions by inhibiting the Na⁺/K⁺-ATPase pump. This inhibition results in an increase in intracellular sodium levels, which subsequently leads to a rise in intracellular calcium concentrations via the sodium-calcium exchange mechanism. The elevated calcium levels enhance the force of myocardial contraction, making it a potent inotropic agent.

Formula: C₄₇H₇₄O₁₉

Purezza: Min. 95%

Colore e forma: Powder

Peso molecolare: 943.08 g/mol

Ref: 3D-MD65946