CAS 17692-51-2

metergolina

Descrizione:

metergolina è un composto chimico classificato come antagonista del recettore della serotonina, che colpisce principalmente il sottotipo di recettore 5-HT2. È noto per le sue potenziali applicazioni nel campo delle neuroscienze e della psicofarmacologia, in particolare nello studio dei disturbi dell'umore e delle condizioni psicotiche. metergolina presenta una struttura complessa che include un moiety indolico, caratteristico di molti composti correlati alla serotonina. La sostanza viene tipicamente somministrata in contesti di ricerca e il suo profilo farmacologico suggerisce che possa influenzare vari sistemi di neurotrasmettitori, potenzialmente influenzando l'umore e la percezione. metergolina è stato studiato per i suoi effetti sulle vie della serotonina sia centrali che periferiche, contribuendo al suo interesse in contesti terapeutici. Tuttavia, come molti composti in questa categoria, può anche presentare effetti collaterali e richiede un'attenta considerazione in termini di dosaggio e somministrazione. Come per qualsiasi agente farmacologico, la ricerca continua è essenziale per comprendere appieno i suoi meccanismi d'azione e i potenziali benefici terapeutici.

Formula: C₂₅H₂₉N₃O₂

InChI: InChI=1/C25H29N3O2/c1-27-14-18(13-26-25(29)30-16-17-7-4-3-5-8-17)11-21-20-9-6-10-22-24(20)19(12-23(21)27)15-28(22)2/h3-10,15,18,21,23H,11-14,16H2,1-2H3,(H,26,29)/p+1/t18-,21+,23+/m0/s1

InChI key: InChIKey=WZHJKEUHNJHDLS-QTGUNEKASA-N

SMILES: CN1C2=C3C([C@@]4([C@@](CC3=C1)(N(C)C[C@H](CNC(OCC5=CC=CC=C5)=O)C4)[H])[H])=CC=C2

Sinonimi:

• (((8-beta)-1,6-Dimethylergolin-8-yl)methyl)carbamic acid phenylmethyl ester
• (+)-N-(Carboxy)-1-methyl-9,10-dihydrolysergamine benzyl ester
• (+)-N-Carboxy-1-methyl-9,10-dihydrolysergamide benzyl ester
• 1,6-Dimethyl-8-beta-carbobenzyloxaminomethyl-10-alpha-ergoline
• 1-Methyl-8-beta-carbobenzyloxyaminomethyl-10-alpha-ergoline
• 1-Methyl-N-carbobenzyloxydihydro-D-lysergamin
• 8β-Carbobenzyloxyaminomethyl-1,6-dimethyl-10α-ergoline
• <span class="text-smallcaps">D</span>-8β-[(Carbobenzoxyamino)methyl]-1,6-dimethyl-10α-ergoline
• <span class="text-smallcaps">D</span>-8β-[(Carboxyamino)methyl]-1,6-dimethylergoline I benzyl ester
• <span class="text-smallcaps">D</span>-N-Carbobenzoxydihydro-1-methyllysergamine I
• <span class="text-smallcaps">D</span>-N-Carboxydihydro-1-methyllysergamine I benzyl ester
• <span class="text-smallcaps">D</span>-[(4,6,6a,7,8,9,10,10a-Octahydro-4,7-dimethyl-10aα-indolo[4,3-fg]quinolin-9β-yl)methyl]carbamic acid benzyl ester
• Ahr 3009
• Benzyl 1,6-dimethylergolin-8beta-ylmethylcarbamat
• Benzyl {[(5Xi,10Beta)-1,6-Dimethylergolin-8-Yl]Methyl}Carbamate
• Benzyl {[(8Beta)-1,6-Dimethylergolin-6-Ium-8-Yl]Methyl}Carbamate
• Benzyl {[(8Beta)-1,6-Dimethylergolin-8-Yl]Methyl}Carbamate
• Carbamic acid, (((8-beta)-1,6-dimethylergolin-8-yl)methyl)-, benzyl ester
• Carbamic acid, (((8-beta)-1,6-dimethylergolin-8-yl)methyl)-, phenylmethyl ester (9CI)
• Carbamic acid, (((8beta)-1,6-dimethylergolin-8-yl)methyl)-, phenylmethyl ester
• Carbamic acid, ((1,6-dimethylergolin-8-beta-yl)methyl)-, benzyl ester
• Carbamic acid, N-[[(8β)-1,6-dimethylergolin-8-yl]methyl]-, phenylmethyl ester
• Carbamic acid, [(1,6-dimethylergolin-8β-yl)methyl]-, benzyl ester
• Carbamic acid, [[(8β)-1,6-dimethylergolin-8-yl]methyl]-, phenylmethyl ester
• Contralac
• D-8-beta-((Carbobenzoxyamino)methyl)-1,6-dimethyl-10-alpha-ergoline
• D-8-beta-((Carboxyamino)methyl)-1,6-dimethylergoline I benzyl ester
• D-N-Carbobenzoxydihydro-1-methyllysergamine I
• D-N-Carboxydihydro-1-methyllysergamine I benzyl ester
• Ergoline, carbamic acid deriv.
• Fi 6337
• Indolo[4,3-fg]quinoline, carbamic acid deriv.
• Liserdol
• Lysergamine, N-carboxy-9,10-dihydro-1-methyl-, benzyl ester
• Lysergamine, N-carboxy-9,10-dihydro-1-methyl-, benzyl ester (7CI)
• MCE
• Metergolin
• Metergolina
• Metergolina [DCIT]
• Metergolina [Spanish]
• Metergoline [INN:BAN]
• Metergolinum
• Metergolinum [INN-Latin]
• Metergolinum [Latin]
• Methergoline
• Substance 355/255
• Unii-1501393Ly5
• Metergoline
• [((8BETA)-1,6-DIMETHYLERGOLIN-8-YL)METHYL]CARBAMIC ACID PHENYLMETHYL ESTER
• (((8-beta)-1,6-dimethylergolin-8-yl)methyl)-carbamicaciphenylmethylest
• d-n-carbobenzoxydihydro-1-methyllysergaminei
• ((1,6-dimethylergolin-8-beta-yl)methyl)-carbamicacibenzylester
• d-n-carboxydihydro-1-methyllysergamineibenzylester
• ahr3009
• N-CBZ-[(8BETA)-1,6-DIMETHYLERGOLIN-8-YL]METHYLAMINE
• (((8-beta)-1,6-dimethylergolin-8-yl)methyl)-carbamicacibenzylester
• METERGOLINE PHENYLMETHYL ESTER

Metergoline

CAS: 17692-51-2

Formula: C₂₅H₂₉N₃O₂

Purezza: 99.89%

Colore e forma: Solid

Peso molecolare: 403.5167

Ref: IN-DA0078UU

Metergoline

CAS: 17692-51-2

Metergoline

Purezza: ≥98%

Peso molecolare: 403.52g/mol

Ref: 54-BUP16416

Metergoline

CAS: 17692-51-2

Formula: C₂₅H₂₉N₃O₂

Peso molecolare: 403.52

Ref: 7W-GP3682

Metergoline

CAS: 17692-51-2

Metergoline (Methergoline) is a dopamine agonist and serotonin antagonist.

Formula: C₂₅H₂₉N₃O₂

Purezza: 99.83% - 99.97%

Colore e forma: Solid

Peso molecolare: 403.52

Ref: TM-T4008

Metergoline

CAS: 17692-51-2

Applications Metergoline is an antagonist at 5-HT1, 5-HT2, and 5-HT7 serotonin receptors. Metergoline is an analgesic; antipyretic.
References Aulakh, et al.: J. Pharmacol. Exp. Ther., 263, 588 (1992), Miller, et al.: Eur. J. Pharmacol., 227, 99 (1992),

Formula: C₂₅H₂₉N₃O₂

Colore e forma: Off White Powder

Peso molecolare: 403.5167

Ref: TR-M226270

[(8b)-1,6-Dimethylergolin-8-yl)methyl]carbamic acid phenylmethyl ester

CAS: 17692-51-2

Ergolines are a class of drugs that bind to serotonin receptors. The ergoline derivative [(8b)-1,6-dimethylergolin-8-yl)methyl]carbamic acid phenylmethyl ester (DMPE) is a potent and selective 5-hydroxytryptamine (5-HT) receptor antagonist. DMPE has been shown to have the ability to increase serum prolactin levels in rats and antagonize the effects of metergoline in monkeys. It also reduces blood pressure in animals by blocking the vasoconstrictor effect of 5-HT on vascular smooth muscle cells.

Formula: C₂₅H₂₉N₃O₂

Purezza: Min. 95%

Colore e forma: White Powder

Peso molecolare: 403.52 g/mol

Ref: 3D-FM12444