CAS 177931-17-8

sauchinone

Descrizione:

sauchinone è un composto chimico che si verifica naturalmente ed è classificato come un sesquiterpene, derivato principalmente dalla specie vegetale *Saururus cernuus*, comunemente nota come coda di lucertola. È caratterizzato dalla sua complessa struttura biciclica, che contribuisce alle sue uniche proprietà chimiche. sauchinone presenta una gamma di attività biologiche, inclusi effetti anti-infiammatori, antiossidanti e potenziali effetti anticancro, rendendolo un argomento di interesse nella ricerca farmacologica. Il composto si trova tipicamente sotto forma di un liquido incolore o giallo pallido e ha un odore distintivo. La sua solubilità varia, essendo più solubile nei solventi organici che in acqua. La formula molecolare di sauchinone riflette la sua composizione di atomi di carbonio, idrogeno e ossigeno, tipica dei sesquiterpeni. A causa delle sue proprietà bioattive, sauchinone è in fase di esplorazione per varie applicazioni terapeutiche, sebbene siano necessari ulteriori studi per comprendere appieno i suoi meccanismi d'azione e i potenziali usi in medicina.

Formula: C₂₀H₂₀O₆

InChI: InChI=1/C20H20O6/c1-9-3-11-13(21)5-17-20(25-8-24-17)19(11)18(10(9)2)12-4-15-16(23-7-22-15)6-14(12)26-20/h4-6,9-11,18-19H,3,7-8H2,1-2H3/t9-,10+,11+,18+,19+,20+/m1/s1

InChI key: InChIKey=GMTJIWUFFXGFHH-WPAOEJHSSA-N

SMILES: C[C@@H]1[C@@]2([C@]3([C@]4(C(=CC(=O)[C@@]3(C[C@H]1C)[H])OCO4)OC=5C2=CC6=C(C5)OCO6)[H])[H]

Sinonimi:

• (5aR,7R,8S,8aR,14aS,14bR)-5a,6,7,8,8a,14b-Hexahydro-7,8-dimethyl-5H-benzo[kl]bis[1,3]dioxolo[4,5-b:4′,5′-g]xanthen-5-one
• (5aR,7R,8S,8aR,14aS,14bR)-7,8-dimethyl-5a,6,7,8,8a,14b-hexahydro-5H-benzo[kl]bis[1,3]dioxolo[4,5-b:4',5'-g]xanthen-5-one
• 5H-Benzo[kl]bis[1,3]dioxolo[4,5-b:4′,5′-g]xanthen-5-one, 5a,6,7,8,8a,14b-hexahydro-7,8-dimethyl-, (5aR,7R,8S,8aR,14aS,14bR)-
• 5H-Benzo[kl]bis[1,3]dioxolo[4,5-b:4′,5′-g]xanthen-5-one, 5a,6,7,8,8a,14b-hexahydro-7,8-dimethyl-, (5aα,7α,8β,8aβ,14aS*,14bβ)-
• 5H-benzo[kl][1,3]dioxolo[4,5-b]-1,3-dioxolo[4,5-g]xanthen-5-one, 5a,6,7,8,8a,14b-hexahydro-7,8-dimethyl-, (5aR,7R,8S,8aR,14aS,14bR)-
• Sauchinone
• (5aα,7α,8β,8aβ,14aS*,14bβ)-5a,6,7,8,8a,14b-Hexahydro-7,8-dimethyl-5H-benzo[kl]bis[1,3]dioxolo[4,5-b:4′,5′-g]xanthen-5-one
• 5H-Benzo[kl]bis[1,3]dioxolo[4,5-b:4',5'-g]xanthen-5-one, 5a,6,7,8,8a,14b-hexahydro-7,8-dimethyl-, (5aR,7R,8S,8aR,14aS,14bR)-
• Sauchinone, 98%, from Saururus chinensis (Lour. ) Baill
• Sauchinone >=98% (HPLC)

Sauchinone

CAS: 177931-17-8

Formula: C₂₀H₂₀O₆

Purezza: 97%

Colore e forma: Solid

Peso molecolare: 356.3692

Ref: IN-DA00AP2Q

Sauchinone

CAS: 177931-17-8

Sauchinone

Purezza: ≥98%

Peso molecolare: 356.37g/mol

Ref: 54-BUP00983

Sauchinone

CAS: 177931-17-8

Sauchinone possesses diverse pharmacological properties, such as hepatoprotective, neuroprotective, anti-inflammatory and anti-tumor effects. Sauchinone protects skin keratinocytes through inhibition of extracellular signal-regulated kinase, c-Jun N-terminal kinase, and p38 MAPK signaling via upregulation of oxidative defense enzymes. Sauchinone can be used for the prevention of functional β-cell damage, it prevents cytokine-induced NO production, iNOS expression,JAK/STAT activation,and NF-κB activation and inhibition of glucose-stimulated insulin secretion (GSIS).

Formula: C₂₀H₂₀O₆

Purezza: 95%~99%

Peso molecolare: 356.374

Ref: BP-BP1258

Sauchinone

CAS: 177931-17-8

Sauchinone: Treats infections, prevents liver fibrosis, reduces oxidative stress, and protects skin and vascular cells.

Formula: C₂₀H₂₀O₆

Purezza: >99.99%

Colore e forma: Solid

Peso molecolare: 356.37

Ref: TM-T6S1572

Sauchinone

CAS: 177931-17-8

Formula: C₂₀H₂₀O₆

Peso molecolare: 356.4

Ref: 7W-GL5788

Sauchinone

CAS: 177931-17-8

Oxygen-heterocyclic compound

Formula: C₂₀H₂₀O₆

Purezza: ≥ 95.0 % (HPLC)

Colore e forma: Powder

Peso molecolare: 356.37

Ref: 5G-83906

Sauchinone

CAS: 177931-17-8

Sauchinone is a natural compound that has shown to be effective in the treatment of bowel disease. This compound is an inhibitor of the toll-like receptor (TLR) and has shown to reduce inflammation and oxidative injury. Sauchinone has been found to increase the production of growth factor-β1, which may be useful for treating injuries such as burns or wounds. The matrix effect of sauchinone on cell culture was investigated using dextran sulfate, which is known to induce apoptosis in cells. Chromatographic analysis showed that sauchinone inhibited DNA binding activity and had an effect on dna binding activity. Molecular docking analysis showed that sauchinone binds with TLR4 and inhibits its signaling pathway, preventing aberrant reactions from occurring. Sauchinone also inhibits NF-κB activation by inhibiting nuclear translocation, thus suppressing inflammatory response.

Formula: C₂₀H₂₀O₆

Purezza: Min. 95%

Colore e forma: Powder

Peso molecolare: 356.37 g/mol

Ref: 3D-FS73944