CAS 1780372-25-9

5-Methyl-N-{6-[(2-methylpyridin-3-yl)oxy]pyridin-3-yl}-6-(trifluoromethyl)-2,3-dihydro-1H-indole-1-carboxamide dihydrochloride

CAS: 1780372-25-9

5-Methyl-N-{6-[(2-methylpyridin-3-yl)oxy]pyridin-3-yl}-6-(trifluoromethyl)-2,3-dihydro-1H-indole-1-carboxamide dihydrochloride is a serotonin receptor antagonist. It is structurally related to the prototypical 5HT2CR agonist, 8-(3-(4-(2,5-dimethoxyphenyl)-1-[1,2,4]triazol--5-- yl)phenoxy)octanoic acid (8OCPA). This drug has been shown to be an effective and selective 5HT2CR antagonist in animal studies. 5HT2CR antagonists have been shown to be effective in treating disorders such as depression and anxiety.

Formula: C₂₂H₂₁Cl₂F₃N₄O₂

Purezza: Min. 95%

Peso molecolare: 501.3 g/mol

Ref: 3D-FWC37225

SB 243213 dihydrochloride

CAS: 1780372-25-9

SB 243213 dihydrochloride is an orally active, selective and high-affinity antagonist of 5-hydroxytryptamine (5-HT)2C receptor(pKi of 9.37 and a pKb of 9.8 for

Formula: C₂₂H₂₁Cl₂F₃N₄O₂

Purezza: 98%

Colore e forma: Solid

Peso molecolare: 501.33

Ref: TM-T12859L