CAS 1784-03-8

L-Arginina, N2-[(4-metilfenil)sulfonil]-, estere metilico, cloridrato (1:1)

Descrizione:

L-Arginina, N2-[(4-metilfenil)sulfonil]-, estere metilico, cloridrato (1:1) è un composto chimico che presenta una combinazione di un amminoacido, L-arginina, e un gruppo sulfonile attaccato a un moiety di metilfenile. Questo composto è caratterizzato dalla sua struttura di amminoacido basico, che include un gruppo guanidinio, contribuendo al suo ruolo in vari processi biologici, come la sintesi proteica e la produzione di ossido nitrico. La presenza dell'estere metilico indica che è un derivato della L-arginina, che può migliorare la sua solubilità e biodisponibilità. La forma cloridrato suggerisce che sia un sale, che tipicamente migliora la stabilità e le proprietà di manipolazione. Questo composto può mostrare varie attività farmacologiche, inclusi potenziali ruoli nella salute cardiovascolare e nella funzione immunitaria. Il suo gruppo sulfonile può anche influenzare la sua reattività e interazione con bersagli biologici. In generale, L-Arginina, N2-[(4-metilfenile)sulfonile]-, estere metilico, cloridrato è di interesse sia nella ricerca biochimica che nelle potenziali applicazioni terapeutiche.

Formula: C₁₄H₂₂N₄O₄S·ClH

InChI: InChI=1S/C14H22N4O4S.ClH/c1-10-5-7-11(8-6-10)23(20,21)18-12(13(19)22-2)4-3-9-17-14(15)16;/h5-8,12,18H,3-4,9H2,1-2H3,(H4,15,16,17);1H/t12-;/m0./s1

InChI key: InChIKey=JIQFFACVQXXHMY-YDALLXLXSA-N

SMILES: S(N[C@@H](CCCNC(=N)N)C(OC)=O)(=O)(=O)C1=CC=C(C)C=C1.Cl

Sinonimi:

• <span class="text-smallcaps">L</span>-Arginine, N²-[(4-methylphenyl)sulfonyl]-, methyl ester, hydrochloride (1:1)
• <span class="text-smallcaps">L</span>-Arginine, N²-[(4-methylphenyl)sulfonyl]-, methyl ester, monohydrochloride
• Arginine, N²-(p-tolylsulfonyl)-, methyl ester, monohydrochloride, <span class="text-smallcaps">L</span>-
• N-alpha-Toluenesulfonylarginine methyl ester hydrochloride
• N-alpha-Tosyl-L-arginine methyl ester hydrochloride
• N-p-Tosyl-L-arginine methyl ester hydrochloride
• N-α-p-Tosyl-L-arginine methyl ester hydrochloride
• N^α-Tosyl-<span class="text-smallcaps">L</span>-arginine methyl ester hydrochloride
• Nalpha-(4-Toluenesulfonyl)-L-Arginine Methyl Ester Hydrochloride
• Tame
• Tos-Arg-OMe . HCl
• Tos-Arg-OMe・HCl
• Tosyl-<span class="text-smallcaps">L</span>-arginine methyl ester hydrochloride
• Tosylarginine methyl ester hydrochloride
• methyl N5-(diaminomethylidene)-N2-[(4-methylphenyl)sulfonyl]-L-ornithinate hydrochloride
• methyl N5-(diaminomethylidene)-N2-[(4-methylphenyl)sulfonyl]ornithinate hydrochloride
• na-P-tosyl-L-arginine methyl*ester hydrochloride
• α-N-Tosyl-<span class="text-smallcaps">L</span>-arginine methyl ester hydrochloride
• L-Arginine, N2-[(4-methylphenyl)sulfonyl]-, methyl ester, hydrochloride (1:1)
• α-N-Tosyl-L-arginine methyl ester hydrochloride
• Nα-Tosyl-L-arginine methyl ester hydrochloride
• L-Arginine, N2-[(4-methylphenyl)sulfonyl]-, methyl ester, monohydrochloride

Nα-Tosyl-L-arginine Methyl Ester Hydrochloride

CAS: 1784-03-8

Formula: C₁₄H₂₂N₄O₄S·HCl

Purezza: >98.0%(T)

Colore e forma: White to Almost white powder to crystal

Peso molecolare: 378.87

Ref: 3B-T0330

Tos-Arg-OMe · HCl

CAS: 1784-03-8

A good substrate for trypsin, thrombin, and urokinase as well as for plasma and glandular kallikreins. By competing for the arginine-binding site in the reactive center of proteases, L-TAME is also able to act as a reversible inhibitor. It suppresses, e.g., the TNF secretion of human leukocytes which is evidently dependent upon the action of serine proteases.

Formula: C₁₄H₂₂N₄O₄S·HCl

Purezza: > 99%

Colore e forma: White Powder

Peso molecolare: 378.88

Ref: 01-4002251

L-Arginine, N2-[(4-methylphenyl)sulfonyl]-, methyl ester, hydrochloride (1:1)

CAS: 1784-03-8

Formula: C₁₄H₂₃ClN₄O₄S

Purezza: 98%

Colore e forma: Solid

Peso molecolare: 378.8748

Ref: IN-DA0025ZQ

TAME hydrochloride

CAS: 1784-03-8

TAME hydrochloride (Tos-Arg-OMe HCl) is a kind od amino acid derivatives.

Formula: C₁₄H₂₃ClN₄O₄S

Purezza: 99.11% - 99.21%

Colore e forma: White Fine Crystalline Powder

Peso molecolare: 378.87

Ref: TM-T1731

TAME hydrochloride

CAS: 1784-03-8

TAME hydrochloride

Purezza: ≥95%

Peso molecolare: 378.87g/mol

Ref: 54-BUP17017

N-α-p-Tosyl-L-Arginine Methyl Ester Hydrochloride

CAS: 1784-03-8

N-α-p-Tosyl-L-Arginine Methyl Ester Hydrochloride

Purezza: 98%

Peso molecolare: 378.87g/mol

Ref: 54-OR1014507

TAME Hydrochloride

CAS: 1784-03-8

Formula: C₁₄H₂₂N₄O₄S·HCl

Purezza: ≥ 98.0%

Colore e forma: White to almost white powder

Peso molecolare: 378.87

Ref: 7W-GM4942

N-α-Tosyl-L-arginine methyl ester hydrochloride

CAS: 1784-03-8

N-alpha-Tosyl-L-arginine methyl ester hydrochloride is a potent inhibitor of the serine protease leishmania. It inhibits the enzyme by binding to its active site and interfering with the enzymatic reaction. This drug has been shown to be effective in treating bladder infections caused by leishmania, although it can cause a decrease in responsiveness in an animal model. N-alpha-Tosyl-L-arginine methyl ester hydrochloride also has anti-HIV activities, which may be due to its ability to inhibit HIV replication. The drug is most likely absorbed through the apical surface of the bladder epithelium and then diffuses into the extracellular space, where it inhibits key enzymes involved in viral replication.

Formula: C₁₄H₂₂N₄O₄S·HCl

Purezza: Min. 95%

Colore e forma: White Off-White Powder

Peso molecolare: 378.88 g/mol

Ref: 3D-FT55915

TAME hydrochloride

CAS: 1784-03-8

Purezza: 98%

Peso molecolare: 378.87

Ref: 10-M03112

N-4-Tosyl-L-arginine Methyl Ester Hydrochloride

CAS: 1784-03-8

Applications N-4-Tosyl-L-arginine Methyl Ester Hydrochloride acts as a synthetic substrate of serine proteases and thus is used to determine serine proteases from diverse organic sources.
References Hummel, B. et al.: Can. J. Biochem. Physiol., 37, 1393 (1959); Matsuda, Y. et al.: J. Biochem. 80, 671 (1976);

Formula: C₁₄H₂₃ClN₄O₄S

Colore e forma: Neat

Peso molecolare: 378.87

Ref: TR-T570000

TAME hydrochloride

CAS: 1784-03-8

Tos-Arg-OMe • HCl is a peptide that has been shown to modulate the responsiveness of cells to sodium channels. Tos-Arg-OMe • HCl may also be useful as an anti-cancer drug, as it inhibits cancer cell growth and induces apoptosis. This peptide has been shown to be an effective treatment for HIV infection by inhibiting viral replication. It also reduces inflammation and prevents the development of other opportunistic infections in animal models.

Formula: C₁₄H₂₂N₄O₄S·ClH

Purezza: Min. 95%

Peso molecolare: 378.87 g/mol

Ref: 3D-STR-3003