CAS 1811-31-0

GalNAc

Descrizione:

GalNAc, o N-acetilgalattosamina, è uno zucchero amminico e un derivato del galattosio. È caratterizzato dalla presenza di un gruppo acetile legato al gruppo amminico nella molecola di galattosio. Questo composto svolge un ruolo cruciale in vari processi biologici, in particolare nella sintesi di glicoproteine e glicolipidi, dove funge da mattoncino per carboidrati complessi. GalNAc è anche coinvolto nei processi di segnalazione e riconoscimento cellulare, influenzando le interazioni cellulari e le risposte immunitarie. Si trova tipicamente sotto forma di una polvere cristallina bianca ed è solubile in acqua. Il composto è non tossico ed è utilizzato in varie applicazioni biochimiche, inclusa la ricerca e lo sviluppo terapeutico. Le sue proprietà strutturali gli consentono di partecipare a varie reazioni enzimatiche, rendendolo significativo nello studio della glicobiologia. In generale, GalNAc è un componente essenziale nella biochimica degli organismi viventi, contribuendo alla complessità e funzionalità delle strutture cellulari.

Formula: C₈H₁₅NO₆

InChI: InChI=1S/C8H15NO6/c1-4(12)9-5(2-10)7(14)8(15)6(13)3-11/h2,5-8,11,13-15H,3H2,1H3,(H,9,12)/t5-,6+,7+,8-/m0/s1

InChI key: InChIKey=MBLBDJOUHNCFQT-OSMVPFSASA-N

SMILES: [C@H]([C@H]([C@H]([C@@H](CO)O)O)O)(NC(C)=O)C=O

Sinonimi:

• 2-(Acetylamino)-2-deoxy-<span class="text-smallcaps">D</span>-galactose
• 2-(Acetylamino)-2-deoxy-D-galactose
• 2-Acetamido-2-deoxy-<span class="text-smallcaps">D</span>-galactose
• 2-Acetamido-2-deoxy-D-galactose
• 2-Deoxy-2-acetamido-<span class="text-smallcaps">D</span>-galactose
• 2-Deoxy-2-acetamido-D-galactose
• 2-N-Acetyl-<span class="text-smallcaps">D</span>-galactosamine
• 2-N-Acetyl-D-galactosamine
• <span class="text-smallcaps">D</span>-Galactose, 2-(acetylamino)-2-deoxy-
• <span class="text-smallcaps">D</span>-N-Acetylgalactosamine
• D-N-Acetylgalactosamine
• GalNAc
• Galactosamine, N-acetyl-, <span class="text-smallcaps">D</span>-
• Galactosamine, N-acetyl-, D-
• Galactose, 2-acetamido-2-deoxy-, <span class="text-smallcaps">D</span>-
• Galactose, 2-acetamido-2-deoxy-, D-
• N-Acetyl-2-amino-2-deoxy-<span class="text-smallcaps">D</span>-galactose
• N-Acetyl-2-amino-2-deoxy-D-galactose
• N-Acetyl-2-amino-2-deoxygalactose
• N-Acetyl-<span class="text-smallcaps">D</span>-galactosamine
• N-Acetyl-D-galactosamine
• N-Acetyl-β-D-galaktosamin
• N-Acetylchondrosamine
• N-Acetylgalactosamine
• N-acetil-β-D-galactosamina
• N-acetyl-β-D-galactosamine

N-Acetyl-D-galactosamine

CAS: 1811-31-0

N-Acetyl-D-galactosamine is the initial O-linked sugar to many serine and threonine residues in protein glycosylation. This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The o

Formula: C₈H₁₅NO₆

Colore e forma: Crystals or crystalline powder, White

Peso molecolare: 221.21

Ref: 02-J66095

D-Galactose, 2-(acetylamino)-2-deoxy-

CAS: 1811-31-0

Formula: C₈H₁₅NO₆

Purezza: 80%

Colore e forma: Solid

Peso molecolare: 221.2078

Ref: IN-DA0022OP

N-Acetyl-D-galactosamine

CAS: 1811-31-0

N-Acetyl-D-galactosamine

Formula: C₈H₁₅NO₆

Purezza: 95%

Colore e forma: white solid

Peso molecolare: 221.21g/mol

Ref: 54-OR7700T

D-N-Acetylgalactosamine

CAS: 1811-31-0

D-N-Acetylgalactosamine

Purezza: ≥98%

Peso molecolare: 221.21g/mol

Ref: 54-BUP18207

N-Acetyl-D-galactosamine

CAS: 1811-31-0

N-Acetyl-D-galactosamine

Formula: C₈H₁₅NO₆

Purezza: 97%

Colore e forma: white to off-white solid

Peso molecolare: 221.21g/mol

Ref: 54-BIM1065

D-N-Acetylgalactosamine

CAS: 1811-31-0

D-N-Acetylgalactosamine (N-Acetyl-D-galactosamine) is an important constituent of brain heteropolysaccharides (glycoproteins).

Formula: C₈H₁₅NO₆

Purezza: 99.79% - 99.91%

Colore e forma: White Crystalline Powder

Peso molecolare: 221.21

Ref: TM-T4708

N-Acetyl-D-galactosamine

Prodotto controllato

CAS: 1811-31-0

Applications N-Acetyl-D-galactosamine (cas# 1811-31-0) is a compound useful in organic synthesis.
References Nakajima, M., et al.: App. Microbiol. Biotechnol., 83, 109 (2009), Singh, S., et al.: Mol. Immunol., 46, 1240 (2009),

Formula: C₈H₁₅NO₆

Colore e forma: Neat

Peso molecolare: 221.2078

Ref: TR-A177000

N-Acetyl-D-galactosamine

CAS: 1811-31-0

N-Acetyl-D-galactosamine (GalNAc) is an aldohexose (2-acetamido-2-deoxygalactose) in which the hydroxyl group at position 2 is replaced by a N-Acetyl group (Collins, 2006). GalNAc forms a key part of both N- and O-linked glycoproteins, glycolipids, gangliosides, blood groups, glycosaminoglycans (chondroitin and dermatan sulfate) and human milk oligosaccharides. The number of acetylgalactosamine residues attached to the IgA O-linked glycans of Crohn'sdisease patients is significantly decreased, and strongly correlated with clinical activity. It is suggested that alterations of GalNAc attachment in IgA may be useful as a novel diagnostic and prognostic marker of Crohn's disease (Inoue, 2012).

Formula: C₈H₁₅NO₆

Purezza: Min. 98%

Colore e forma: White Powder

Peso molecolare: 221.21 g/mol

Ref: 3D-MA04390

N-Acetyl-D-galactosamine

CAS: 1811-31-0

N-acetyl D-galactosamine (GalNAc) is an aldohexose (2-acetamido-2-deoxygalactose) in which the hydroxyl group at position 2 is replaced by a N-acetyl group (Collins, 2006). GalNAc forms a key part of both N- and O-linked glycoproteins, glycolipids, gangliosides, blood groups, glycosaminoglycans (chondroitin and dermatan sulfate) and human milk oligosaccharides. The number of GalNAc residues attached to the IgA O-linked glycans of Crohns Disease patients was significantly decreased, and strongly correlated with clinical activity. It is suggested that alterations of GalNAc attachment in IgA may be useful as a novel diagnostic and prognostic marker of Crohns Disease (Inoue, 2012).

Formula: C₈H₁₅NO₆

Purezza: Min. 99.0 Area-%

Peso molecolare: 221.21 g/mol

Ref: 3D-A-1170

N-((2R,3R,4R,5R)-3,4,5,6-Tetrahydroxy-1-oxohexan-2-yl)acetamide

CAS: 1811-31-0

Formula: C₈H₁₅NO₆

Purezza: 80%

Colore e forma: Solid, Crystalline or Powder

Peso molecolare: 221.209

Ref: 10-F239286

N-Acetyl-D-galactosamine, plant-based

CAS: 1811-31-0

N-Acetyl-D-galactosamine (GalNAc) is an aldohexose. It forms a key part of both N- and O-linked glycoproteins, glycolipids, gangliosides, blood groups, glycosaminoglycans (chondroitin and dermatan sulfate) and human milk oligosaccharides.This N-Acetyl-D-galactosamine product (MA184543) is plant-based and produced synthetically from Arabic gum.GalNAc clusters and derivatives, typically composed of three (or more) GalNAc moieties arranged in a specific spatial configuration, are a powerful tool for targeted delivery of nucleic acid therapeutics, specifically in liver targeted therapies. These multivalent ligands effectively bind and internalize via the asialoglycoprotein receptor (ASGPR) expressed on the surface of hepatocytes.

Formula: C₈H₁₅NO₆

Purezza: Min. 97 Area-%

Peso molecolare: 221.21 g/mol

Ref: 3D-MA184543