CAS 18559-94-9

Salbutamolo

Descrizione:

Salbutamolo, noto anche come albuterolo in alcune regioni, è un agonista selettivo dei recettori adrenergici beta-2 utilizzato principalmente come broncodilatatore nel trattamento dell'asma e della broncopneumopatia cronica ostruttiva (BPCO). La sua formula chimica è C13H21NO3 e presenta un gruppo idrossilico fenolico, che contribuisce alla sua attività farmacologica. Salbutamolo agisce stimolando i recettori adrenergici beta-2 nel muscolo liscio delle vie aeree, portando al rilassamento e alla dilatazione dei passaggi bronchiali, migliorando così il flusso d'aria e alleviando i sintomi del broncospasmo. La sostanza viene tipicamente somministrata per inalazione, sebbene siano disponibili anche forme orali e endovenose. Salbutamolo ha una emivita relativamente breve, richiedendo più dosi per un effetto sostenuto. È generalmente ben tollerato, ma gli effetti collaterali potenziali possono includere tremori, palpitazioni e mal di testa. Essendo un farmaco ampiamente utilizzato, Salbutamolo è incluso nelle liste di medicinali essenziali ed è soggetto a regolamentazioni riguardanti il suo uso nello sport a causa del suo potenziale di miglioramento delle prestazioni.

Formula: C₁₃H₂₁NO₃

InChI: InChI=1S/C13H21NO3/c1-13(2,3)14-7-12(17)9-4-5-11(16)10(6-9)8-15/h4-6,12,14-17H,7-8H2,1-3H3

InChI key: InChIKey=NDAUXUAQIAJITI-UHFFFAOYSA-N

SMILES: C(CNC(C)(C)C)(O)C1=CC(CO)=C(O)C=C1

Sinonimi:

• (.+-.)-Albuterol
• (.+-.)-Salbutamol
• 1,3-Benzenedimethanol, α¹-[[(1,1-dimethylethyl)amino]methyl]-4-hydroxy-
• 1-(tert-Butylaminomethyl)-4-hydroxy-m-xylene-α1,α3-diol
• 1-(tert-Butylaminomethyl)-4-hydroxy-m-xylene-α¹,α³-diol
• 2-(tert-Butylamino)-1-[(4-hydroxy-3-hydroxymethyl)phenyl]ethanol
• 4-Hydroxy-3-(hydroxymethyl)-α-[[(1,1-dimethylethyl)amino]methyl]benzenemethanol
• <span class="text-smallcaps">DL</span>-N-tert-Butyl-2(4-hydroxy-3-hydroxymethylphenyl)2-hydroxyethylamine
• Ah 3365
• Airomir
• DL-N-tert-Butyl-2(4-hydroxy-3-hydroxymethylphenyl)2-hydroxyethylamine
• Eolene
• Etinoline
• ProAir HFA
• Proventil HFA
• Proventil Inhaler
• Sabumol
• Salamol EB
• Salbiar
• Saventol
• Spreor
• Sultanol
• Sultanol N
• Ventalin Inhaler
• Ventolin
• Ventoline
• Volmax
• dl-Albuterol
• dl-Salbutamol
• m-Xylene α,α'-diol, α-[(tert-butylamino)methyl]-4-hydroxy-
• m-Xylene-α,α'-diol, α1-[(tert-butylamino)methyl]-4-hydroxy-
• m-Xylene-α,α′-diol, α¹-[(tert-butylamino)methyl]-4-hydroxy-
• α1-tert-Butylaminomethyl-4-hydroxy-m-xylene-α1,α3-diol
• α¹-[[(1,1-Dimethylethyl)amino]methyl]-4-hydroxy-1,3-benzenedimethanol
• α¹-tert-Butylaminomethyl-4-hydroxy-m-xylene-α¹,α³-diol
• α1-[[(1,1-Dimethylethyl)amino]methyl]-4-hydroxy-1,3-benzenedimethanol

d,l-Salbutamol, 1mg/ml in Ethanol

CAS: 18559-94-9

Colore e forma: Single Solution

Ref: LP-SAL-117-FB-1LE

Salbutamol

CAS: 18559-94-9

Salbutamol

Formula: C₁₃H₂₁NO₃

Purezza: 99.8%

Colore e forma: Off-White

Peso molecolare: 239.15214

Ref: 47-451

SALBUTAMOL FOR PEAK IDENTIFICATION CRS

CAS: 18559-94-9

SALBUTAMOL FOR PEAK IDENTIFICATION CRS

Colore e forma: Added Modified

Ref: 41-Y0002386

SALBUTAMOL RS

CAS: 18559-94-9

SALBUTAMOL RS

Formula: C₁₃H₂₁NO₃

Colore e forma: Added Modified

Peso molecolare: 239.3107

Ref: 41-ICRS47064

SALBUTAMOL CRS

CAS: 18559-94-9

SALBUTAMOL CRS

Formula: C₁₃H₂₁NO₃

Colore e forma: Added Modified

Peso molecolare: 239.3107

Ref: 41-S0100000

Albuterol

CAS: 18559-94-9

Aromatic amino-alcohol-phenols, aromatic amino-acid-phenols and other aromatic amino compounds with oxygen function

Formula: C₁₃H₂₁NO₃

Colore e forma: White Off-White Crystalline Powder

Peso molecolare: 239.15214

Ref: 45-1012600

Salbutamol

CAS: 18559-94-9

Salbutamol (Albuterol) stimulates beta2-adrenergic receptors in the lungs, thereby activating the enzyme adenylate cyclase that catalyzes the conversion of ATP to cyclic-3', 5'-adenosine monophosphate (cAMP).

Formula: C₁₃H₂₁NO₃

Purezza: 91.59% - 99.9%

Colore e forma: White To Off-White Crystalline Solid Solid

Peso molecolare: 239.31

Ref: TM-T1139

Salbutamol (Albuterol)

CAS: 18559-94-9

Formula: C₁₃H₂₁NO₃

Colore e forma: White To Off-White Solid

Peso molecolare: 239.32

Ref: 4Z-S-171

Salbutamol

CAS: 18559-94-9

Salbutamol

Colore e forma: Powder

Peso molecolare: 239.31g/mol

Ref: 54-BIS7017

Salbutamol

CAS: 18559-94-9

Formula: C₁₃H₂₁NO₃

Purezza: 98.0 - 101.0 % (dried basis)

Colore e forma: White to off-white powder

Peso molecolare: 239.31

Ref: 7W-GP7722

(±)-Albuterol-d9 (tert-butyl-d9)

CAS: 1173021-73-2, 18559-94-9

Purezza: 98 atom % D

Peso molecolare: 248.37

Ref: 3U-D7928

(±)-Albuterol-d3 (3-hydroxymethyl-d2; alpha-d1)

CAS: 1219798-60-3, 18559-94-9

Purezza: 98 atom % D

Colore e forma: White Solid

Peso molecolare: 242.33

Ref: 3U-D5921

Salbutamol 100 µg/mL in Acetonitrile

CAS: 18559-94-9

Formula: C₁₃H₂₁NO₃

Colore e forma: Single Solution

Peso molecolare: 239.31

Ref: 04-XA16903000AL

Salbutamol

CAS: 18559-94-9

Formula: C₁₃H₂₁NO₃

Colore e forma: Neat

Peso molecolare: 239.31

Ref: 04-C16903000

d,l-Salbutamol

CAS: 18559-94-9

Colore e forma: Neat

Ref: LP-SAL-117-FB-10

rac Albuterol

Prodotto controllato

CAS: 18559-94-9

Applications rac Albuterol is a β2-adrenoceptor agonist. Bronchodilator; tocolytic. This compound is a contaminant of emerging concern (CECs).
References Miyagawa, N., et al.: Biol. Pharm. Bull., 31, 2260 (2008), Gonzalez-Munoz, C., et al.: Eur. J. Pharmacol., 607, 151 (2009), Kern, C., et al.: J. Med. Chem., 52, 1773 (2009),

Formula: C₁₃H₂₁NO₃

Colore e forma: White

Peso molecolare: 239.31

Ref: TR-A514501

(±)-Salbutamol

Prodotto controllato

CAS: 18559-94-9

Salbutamol is a bronchodilator with selective beta-2 receptor activity. It is used to prevent and treat asthma and other respiratory disorders. Salbutamol has been shown to improve lung function in children with asthma and may be effective in the treatment of chronic obstructive pulmonary disease (COPD). The cardiac effects of salbutamol are related to its ability to increase blood flow through the lungs, which reduces the workload of the heart. Salbutamol also has an effect on maternal blood flow and may have some anti-inflammatory properties. Salbutamol has been shown to inhibit the transfection of DNA into cells by benzalkonium chloride, a chemical that is commonly used as a preservative in laboratory experiments. Salbutamol also inhibits eosinophil cationic protein production, which may be due to its ability to inhibit transcriptional activation of this protein or its ability to alter gene expression at post-transcriptional levels.

Formula: C₁₃H₂₁NO₃

Purezza: Min. 95%

Colore e forma: White Powder

Peso molecolare: 239.31 g/mol

Ref: 3D-FA61527

Albuterol-13C6

Prodotto controllato

CAS: 18559-94-9

Formula: C₆C₇H₂₁NO₃

Colore e forma: Neat

Peso molecolare: 245.267

Ref: TR-A514504

Salbutamol Impurity O Sulfate Salt

Prodotto controllato

CAS: 18559-94-9

Formula: (C₁₅H₂₅NO₃)·(H₂SO₄)

Colore e forma: Neat

Peso molecolare: 632.81

Ref: TR-S085555

(±)-Salbutamol

Prodotto controllato

CAS: 18559-94-9

(±)-Salbutamol is a racemic mixture of a beta-2 adrenergic agonist, which is synthetically derived. This compound functions primarily by selectively stimulating beta-2 adrenergic receptors, which are predominantly located on the smooth muscle cells lining the airways. The activation of these receptors leads to the relaxation of bronchial muscle tissue, resulting in bronchodilation and improved airflow.

Formula: C₁₃H₂₁NO₃

Peso molecolare: 239.31 g/mol

Ref: 3D-Q-201695