CAS 1866-15-5

Ioduro di acetiltiocolina

Descrizione:

Ioduro di acetiltiocolina è un composto di ammonio quaternario che funge da substrato per l'enzima acetilcolinesterasi ed è spesso utilizzato nella ricerca biochimica, in particolare negli studi relativi alla neurotrasmissione. È un analogo sintetico del neurotrasmettitore acetilcolina, caratterizzato da un gruppo tioetere che ne migliora stabilità e reattività. Il composto è tipicamente un solido cristallino bianco o bianco sporco, solubile in acqua e solventi organici polari. La sua struttura include un gruppo acetile legato a una parte di tiocolina, che contribuisce alla sua capacità di imitare l'azione dell'acetilcolina sui recettori colinergici. Ioduro di acetiltiocolina è comunemente utilizzato in saggi per misurare l'attività enzimatica e in studi farmacologici per indagare le vie di segnalazione colinergiche. A causa della sua natura quaternaria, non attraversa facilmente le membrane biologiche, rendendolo utile per studi in vitro. Devono essere osservate precauzioni di sicurezza quando si maneggia questo composto, poiché potrebbe comportare rischi per la salute se ingerito o inalato.

Formula: C₇H₁₆NOS·I

InChI: InChI=1S/C7H16NOS.HI/c1-7(9)10-6-5-8(2,3)4;/h5-6H2,1-4H3;1H/q+1;/p-1

InChI key: InChIKey=NTBLZMAMTZXLBP-UHFFFAOYSA-M

SMILES: C(CSC(C)=O)[N+](C)(C)C.[I-]

Sinonimi:

• (2-Mercaptoethyl)trimethylammonium iodide acetate
• 2-(Acetylsulfanyl)-N,N,N-trimethylethanaminium iodide
• 2-Acetylthioethyltrimethylammonium Iodide
• Acetic acid, thio-, S-ester with (2-mercaptoethyl)trimethylammonium iodide
• Acetylthiocholine diiodide
• Acetylthiocholine iodide
• Ammonium, (2-mercaptoethyl)trimethyl-, iodide, acetate
• Ethanaminium, 2-(acetylthio)-N,N,N-trimethyl-, iodide
• [2-(Acetylsulfanyl)ethyl]trimethylazanium iodide
• [2-(Acetylthio)ethyl](trimethyl)ammonium iodide
• ethanaminium, 2-(acetylthio)-N,N,N-trimethyl-, iodide (1:1)

Acetylthiocholine Iodide

CAS: 1866-15-5

Formula: C₇H₁₆INOS

Purezza: >98.0%(T)

Colore e forma: White to Almost white powder to crystal

Peso molecolare: 289.18

Ref: 3B-A0116

Acetylthiocholine iodide

CAS: 1866-15-5

Formula: C₇H₁₆INOS

Purezza: 98%

Colore e forma: Solid, White - Almost white powder

Peso molecolare: 289.18

Ref: 10-F228086

S-Acetylthiocholine iodide, 98%

CAS: 1866-15-5

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Sci

Formula: C₇H₁₆INOS

Purezza: 98%

Colore e forma: White, Crystals or powder or crystalline powder

Peso molecolare: 289.18

Ref: 02-A16802

Ethanaminium, 2-(acetylthio)-N,N,N-trimethyl-, iodide

CAS: 1866-15-5

Formula: C₇H₁₆INOS

Purezza: 98%

Colore e forma: Solid

Peso molecolare: 289.1775

Ref: IN-DA00I1TX

Acetylthiocholine iodide

CAS: 1866-15-5

Formula: C₇H₁₆INOS

Purezza: (Titration) ≥ 98.0%

Colore e forma: White or almost white crystalline powder

Peso molecolare: 289.18

Ref: 7W-GE4789

[2-(acetylthio)ethyl](trimethyl)ammonium iodide

CAS: 1866-15-5

[2-(acetylthio)ethyl](trimethyl)ammonium iodide

Purezza: 98%

Peso molecolare: 289.1775g/mol

Ref: 54-OR27854

S-Acetylthiocholine iodide

CAS: 1866-15-5

S-Acetylthiocholine iodide

Formula: C₇H₁₆NOS·I

Purezza: 98%

Colore e forma: white solid

Peso molecolare: 289.1775g/mol

Ref: 54-BIA4001

Acetylthiocholine Iodide

Prodotto controllato

CAS: 1866-15-5

Applications Acetylthiocholine Iodide functions as a potential biomarkers for the dictation of diseases or biological conditions (in-vitro) in marines and also functions in ecotoxically studies in marine.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Gomes, I. D. L., et al.: Mar. Pollut.Bull. (2014), 85(1), 179-185

Formula: C₇H₁₆NOS·I

Colore e forma: Neat

Peso molecolare: 289.1775

Ref: TR-A164610

S-Acetylthiocholine iodide

CAS: 1866-15-5

S-Acetylthiocholine iodide is an acetylcholinesterase substrate for the colorimetric determination of acetylcholinesterase activity. In this assay the production of thiocholine formed in the hydrolysis of acetylthiocholine is measured by coupling of the reactive thiol with DTNB to give a thionitrobenzoate (TNB). The TNB is a yellow anion and its formation can be measured spectrometrically. Nicotinic acetylcholine receptor agonist.

Formula: C₇H₁₆INOS

Peso molecolare: 289.18 g/mol

Ref: 3D-A-1700

S-Acetylthiocholine iodide

CAS: 1866-15-5

S-Acetylthiocholine iodide is an inhibitor of acetylcholinesterase. This compound has been shown to be effective in a variety of biochemical and experimental models, with the optimum concentration at 5-10 mM. S-Acetylthiocholine iodide has also been shown to have inhibitory properties against other enzymes, such as brain functions and choline esterase. The inhibition of these enzymes may lead to the development of novel biomarkers for the diagnosis of diseases such as Alzheimer's disease, Parkinson's disease, and amyotrophic lateral sclerosis.

Formula: C₇H₁₆INOS

Purezza: Min. 95%

Colore e forma: White Powder

Peso molecolare: 289.18 g/mol

Ref: 3D-FA33157

S-Acetylthiocholine Iodide extrapure AR, 99%

CAS: 1866-15-5

Formula: C₇H₁₆NOSI

Purezza: min. 99%

Colore e forma: White to off - white, Crystalline powder, Clear

Peso molecolare: 289.17

Ref: SR-38998