CAS 186826-70-0

(3β)-16-[(3β)-3-Hydroxyandrosta-5,16-dien-17-yl]-17-(3-pyridinyl)-androsta-5,16-dien-3-ol

Prodotto controllato

CAS: 186826-70-0

Applications (3β)-16-[(3β)-3-Hydroxyandrosta-5,16-dien-17-yl]-17-(3-pyridinyl)-androsta-5,16-dien-3-ol is a derivative of Abiraterone (A108490), which is a steroidal cytochrome P 450 17α-hydroxylase-17,20-lyase inhibitor (CYP17), is currently undergoing phase II clinical trials as a potential drug for the treatment of androgen-dependent prostate cancer.
References Denis, L., et al.: Cancer, 72, 3888 (1993), Potter, G.A., et al.: J. Med. Chem., 38, 2463 (1995), Denmeade, S., et al.: Nat. Rev., 2, 389(2002), Scher, H., et al.: J. Clin. Oncol., 23, 8253 (2005),

Formula: C₄₃H₅₇NO₂

Colore e forma: Neat

Peso molecolare: 619.918

Ref: TR-A108545

Abiraterone dimer impurity

Prodotto controllato

CAS: 186826-70-0

Abiraterone dimer impurity is a drug product that is used as an analytical standard for HPLC, as well as in research and development of drugs. It is also a metabolite of abiraterone and has been detected in the urine of patients receiving the drug. Abiraterone dimer impurity is found in trace amounts in abiraterone acetate but its pharmacological significance is not known. This impurity has been detected in the urine of patients receiving abiraterone acetate therapy.

Formula: C₄₃H₅₇NO₂

Purezza: Min. 95%

Peso molecolare: 619.92 g/mol

Ref: 3D-IA176064

Abiraterone Dimer

CAS: 186826-70-0

Formula: C₄₃H₅₇NO₂

Peso molecolare: 619.92

Ref: ST-EA-CP-A67093