CAS 187618-60-6

N5-[[[(2,3-Diidro-2,2,4,6,7-pentametil-5-benzofuranil)sulfonil]amino]iminometil]-N2-[(9H-fluoren-9-ilmetossi)carbonil]-D-ornitina

Descrizione:

La sostanza chimica nota come N5-[[[(2,3-Diidro-2,2,4,6,7-pentametil-5-benzofuranil)sulfonil]amino]iminometil]-N2-[(9H-fluoren-9-ilmetossi)carbonil]-D-ornitina, con il numero CAS 187618-60-6, è un composto organico complesso caratterizzato dalla sua struttura intricata che include uno scheletro di D-ornitina, un gruppo sulfonamide e vari sostituenti aromatici e alifatici. Questo composto presenta una porzione di benzofurano, che contribuisce alla sua potenziale attività biologica, e un gruppo protettivo di fluorenilmetossicarbonile (Fmoc), comunemente usato nella sintesi di peptidi. La presenza di più gruppi metilici aumenta la sua lipofilia, influenzando potenzialmente la sua solubilità e interazione con le membrane biologiche. Il gruppo sulfonilamminico suggerisce possibili applicazioni in chimica medicinale, in particolare nello sviluppo di farmaci mirati a specifiche vie biologiche. In generale, le caratteristiche strutturali uniche del composto possono conferire proprietà specifiche di interesse nella ricerca e nello sviluppo nei campi della biochimica e della farmacologia.

Formula: C₃₄H₄₀N₄O₇S

InChI: InChI=1S/C34H40N4O7S/c1-19-20(2)30(21(3)26-17-34(4,5)45-29(19)26)46(42,43)38-32(35)36-16-10-15-28(31(39)40)37-33(41)44-18-27-24-13-8-6-11-22(24)23-12-7-9-14-25(23)27/h6-9,11-14,27-28H,10,15-18H2,1-5H3,(H,37,41)(H,39,40)(H3,35,36,38)/t28-/m1/s1

InChI key: InChIKey=HNICLNKVURBTKV-MUUNZHRXSA-N

SMILES: C(OC(N[C@H](CCCNC(NS(=O)(=O)C=1C(C)=C2C(=C(C)C1C)OC(C)(C)C2)=N)C(O)=O)=O)C3C=4C(C=5C3=CC=CC5)=CC=CC4

Sinonimi:

• (E)-N5-(amino{[(2,2,4,6,7-pentamethyl-2,3-dihydro-1-benzofuran-5-yl)sulfonyl]amino}methylidene)-N2-(tert-butoxycarbonyl)-D-ornithine
• <span class="text-smallcaps">D</span>-Ornithine, N⁵-[[[(2,3-dihydro-2,2,4,6,7-pentamethyl-5-benzofuranyl)sulfonyl]amino]iminomethyl]-N²-[(9H-fluoren-9-ylmethoxy)carbonyl]-
• N'-[(2,3-Dihydro-2,2,4,6,7-pentamethyl-5-benzofuranyl)sulfonyl]-N-[(9H-fluoren-9-ylmethoxy)carbonyl]-D-arginine
• N⁵-[[[(2,3-Dihydro-2,2,4,6,7-pentamethyl-5-benzofuranyl)sulfonyl]amino]iminomethyl]-N²-[(9H-fluoren-9-ylmethoxy)carbonyl]-<span class="text-smallcaps">D</span>-ornithine
• D-Ornithine, N5-[[[(2,3-dihydro-2,2,4,6,7-pentamethyl-5-benzofuranyl)sulfonyl]amino]iminomethyl]-N2-[(9H-fluoren-9-ylmethoxy)carbonyl]-
• 1: PN: WO2022213118 TABLE: 12 claimed sequence
• N5-[[[(2,3-Dihydro-2,2,4,6,7-pentamethyl-5-benzofuranyl)sulfonyl]amino]iminomethyl]-N2-[(9H-fluoren-9-ylmethoxy)carbonyl]-D-ornithine

Nα-[(9H-Fluoren-9-ylmethoxy)carbonyl]-Nω-(2,2,4,6,7-pentamethyldihydrobenzofuran-5-sulfonyl)-D-arginine

CAS: 187618-60-6

Formula: C₃₄H₄₀N₄O₇S

Purezza: >98.0%(T)(HPLC)

Colore e forma: White to Almost white powder to crystal

Peso molecolare: 648.78

Ref: 3B-F0875

Fmoc-D-Arg(Pbf)-OH

CAS: 187618-60-6

Bachem ID: 4025744.

Formula: C₃₄H₄₀N₄O₇S

Purezza: 99.9%

Colore e forma: White

Peso molecolare: 648.78

Ref: 01-4025744

D-Ornithine,N5-[[[(2,3-dihydro-2,2,4,6,7-pentamethyl-5-benzofuranyl)sulfonyl]amino]iminomethyl]-N2-[(9H-fluoren-9-ylmethoxy)carbonyl]-

CAS: 187618-60-6

Formula: C₃₄H₄₀N₄O₇S

Purezza: 97%

Colore e forma: Solid

Peso molecolare: 648.7690

Ref: IN-DA00I1VL

Fmoc-D-Arg(Pbf)-OH

CAS: 187618-60-6

Fmoc-D-Arg(Pbf)-OH

Purezza: 98%

Peso molecolare: 648.77g/mol

Ref: 54-OR1013341

Fmoc-D-Arg(Pbf)-OH

CAS: 187618-60-6

Formula: C₃₄H₄₀N₄O₇S

Purezza: ≥ 98.0%

Colore e forma: White to almost white powder or crystals

Peso molecolare: 648.77

Ref: 7W-GM3013

Fmoc-D-Arg(Pbf)-OH

CAS: 187618-60-6

Formula: C₃₄H₄₀N₄O₇S

Peso molecolare: 648.8

Ref: ST-EA-CP-L28024

Fmoc-D-Arg(Pbf)-OH

CAS: 187618-60-6

Fmoc-D-Arg(Pbf)-OH is a synthetic D-arginine peptide. It is an inhibitor of protein interactions, activator of ligand, and a research tool for receptor binding studies. Fmoc-D-Arg(Pbf)-OH has been used to characterize ion channels and antibody binding sites. This molecule has high purity with no impurities or traces of solvent.

Formula: C₃₄H₄₀N₄O₇S

Purezza: Min. 95%

Peso molecolare: 648.78 g/mol

Ref: 3D-FDR-1801-PI

Fmoc-D-Arg(Pbf)-OH

CAS: 187618-60-6

Fmoc-D-Arg(Pbf)-OH is a synthetic peptide that can inhibit the growth of cancer cells. It has been shown to inhibit protease activity in mitochondria and inhibit mitochondrial membrane potential. The uptake of Fmoc-D-Arg(Pbf)-OH by neutrophils is dependent on the presence of superparamagnetic iron nanoparticles, which are taken up by phagocytic cells and used for oxidative burst. Fmoc-D-Arg(Pbf)-OH has a high affinity for mammalian cells but not for bacterial or fungal cells.

Formula: C₃₄H₄₀N₄O₇S

Purezza: Min. 95%

Peso molecolare: 648.77 g/mol

Ref: 3D-FF40496

Fmoc-D-Arg(pbf)-OH

CAS: 187618-60-6

M06294 - Fmoc-D-Arg(pbf)-OH

Formula: C₃₄H₄₀N₄O₇S

Purezza: 95%

Colore e forma: Solid, White powder

Peso molecolare: 648.78

Ref: 10-M06294