CAS 1879-72-7

(11β,16α)-9-Fluoro-11,17-diidrossi-16-metil-21-(1-osso-3-fenilpropossi)pregna-1,4-diene-3,20-dione

Descrizione:

La sostanza chimica nota come "(11β,16α)-9-Fluoro-11,17-diidrossi-16-metil-21-(1-osso-3-fenilpropossi)pregna-1,4-diene-3,20-dione," con il numero CAS 1879-72-7, è un corticosteroide sintetico. Mostra proprietà anti-infiammatorie e immunosoppressive, rendendola utile in varie applicazioni terapeutiche, in particolare nel trattamento di condizioni come asma, allergie e disturbi autoimmuni. La struttura di questo composto presenta un atomo di fluoro, gruppi idrossilici e una catena laterale di fenilpropossido, contribuendo alla sua attività biologica e farmacocinetica. La presenza dello scheletro steroideo pregnano è caratteristica dei corticosteroidi, che derivano dal colesterolo. La stereochimica specifica di questo composto, indicata dalla nomenclatura, gioca un ruolo cruciale nella sua interazione con i recettori dei glucocorticoidi, influenzando la sua efficacia e potenza. Come molti corticosteroidi, può anche avere effetti collaterali, inclusi potenziali impatti sul metabolismo e sulla funzione immunitaria, richiedendo una considerazione attenta nel suo uso clinico.

Formula: C₃₁H₃₇FO₆

InChI: InChI=1/C31H37FO6/c1-19-15-24-23-11-10-21-16-22(33)13-14-28(21,2)30(23,32)25(34)17-29(24,3)31(19,37)26(35)18-38-27(36)12-9-20-7-5-4-6-8-20/h4-8,13-14,16,19,23-25,34,37H,9-12,15,17-18H2,1-3H3/t19-,23+,24+,25+,28+,29+,30+,31+/m1/s1

InChI key: InChIKey=CTKMBLPPDDQOSU-JPYVRCQISA-N

SMILES: F[C@@]12[C@]([C@]3([C@@](C)([C@](C(COC(CCC4=CC=CC=C4)=O)=O)(O)[C@H](C)C3)C[C@@H]1O)[H])(CCC=5[C@]2(C)C=CC(=O)C5)[H]

Sinonimi:

• (11Beta,16Alpha)-9-Fluoro-11,17-Dihydroxy-16-Methyl-3,20-Dioxopregna-1,4-Dien-21-Yl 3-Phenylpropanoate
• Dexamethasone 21-hydrocinnamate
• Dexamethasone 21-phenylpropionate
• Pregna-1,4-diene-3,20-dione, 9-fluoro-11,17-dihydroxy-16-methyl-21-(1-oxo-3-phenylpropoxy)-, (11β,16α)-
• Pregna-1,4-diene-3,20-dione, 9-fluoro-11β,17,21-trihydroxy-16α-methyl-, 21-hydrocinnamate
• Dexamethasone 21-(3-phenylpropionate)
• (11β,16α)-9-Fluoro-11,17-dihydroxy-16-methyl-21-(1-oxo-3-phenylpropoxy)pregna-1,4-diene-3,20-dione
• Dexamethasone Phenylpropionate
• Pregna-1,4-diene-3,20-dione, 9-fluoro-11,17-dihydroxy-16-methyl-21-(1-oxo-3-phenylpropoxy)-, (11.beta.,16.alpha.)-
• [2-[(8S,9R,10S,11S,13S,14S,16R,17R)-9-fluoro-11,17-dihydroxy-10,13,16-trimethyl-3-oxo-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-17-yl]-2-oxoethyl] 3-phenylpropanoate
• 9-Fluoro-11β,17-dihydroxy-16α-methyl-21-(1-oxo-3-phenylpropoxy)pregna-1,4-diene-3,20-dione

Dexamethasone Phenylpropionate

CAS: 1879-72-7

Formula: C₃₁H₃₇FO₆

Purezza: 95%

Peso molecolare: 524.6203

Ref: IN-DA002GK5

Dexamethasone Phenylpropionate

CAS: 1879-72-7

Formula: C₃₁H₃₇FO₆

Colore e forma: White To Off-White Solid

Peso molecolare: 524.63

Ref: 4Z-D-3629

Dexamethasone Phenylpropionate

Prodotto controllato

CAS: 1879-72-7

Formula: C₃₁H₃₇FO₆

Colore e forma: Neat

Peso molecolare: 524.62

Ref: TR-D222830

Dexamethasone 21-(3-phenylpropionate)

CAS: 1879-72-7

Dexamethasone 21-(3-phenylpropionate) is a corticosteroid that is used for the treatment of a variety of inflammatory skin conditions. Dexamethasone 21-(3-phenylpropionate) has been shown to be effective in the treatment of cutaneous lesions in mice and rabbits. This drug also has an anti-inflammatory effect, which may be due to its ability to inhibit cytokine production. Dexamethasone 21-(3-phenylpropionate) is not metabolized by liver enzymes and has a long half life, making it more predictable than prednisolone. This medication should not be used during pregnancy or if you are trying to become pregnant, as it may cause abortion or premature birth. It should also not be used by women who are breastfeeding, as it can pass through breast milk and affect the baby.

Formula: C₃₁H₃₇FO₆

Purezza: Min. 95%

Colore e forma: Powder

Peso molecolare: 524.62 g/mol

Ref: 3D-FD31959

Dexamethasone Phenylpropionate

CAS: 1879-72-7

Formula: C₃₁H₃₇FO₆

Peso molecolare: 524.63

Ref: ST-EA-CP-D17070