CAS 189028-95-3

(4S)-3-[(5S)-5-(4-fluorofenile)-5-idrossi-1-ossopentile]-4-fenil-2-ossazolidinone

Descrizione:

La sostanza chimica nota come (4S)-3-[(5S)-5-(4-fluorofenile)-5-idrossi-1-ossopentile]-4-fenil-2-ossazolidinone, con il numero CAS 189028-95-3, è caratterizzata dalla sua struttura centrale di oxazolidinone, che è un composto eterociclico a cinque membri contenente sia azoto che ossigeno. Questo composto presenta un centro chirale nella posizione 4 dell'anello di oxazolidinone, contribuendo alla sua stereochimica e potenziale attività biologica. La presenza di un gruppo 4-fluorofenile e di un moiety di idrossicetone suggerisce che potrebbe esibire interazioni significative con bersagli biologici, influenzando possibilmente le sue proprietà farmacologiche. La struttura molecolare del composto indica potenziale per applicazioni in chimica medicinale, in particolare nello sviluppo di antibiotici o altri agenti terapeutici. La sua solubilità, stabilità e reattività dipenderebbero dai gruppi funzionali specifici e dalla loro disposizione, il che può influenzare il suo comportamento nei sistemi biologici. In generale, questo composto rappresenta una classe di molecole che possono avere importanti implicazioni nella scoperta e nello sviluppo di farmaci.

Formula: C₂₀H₂₀FNO₄

InChI: InChI=1S/C20H20FNO4/c21-16-11-9-15(10-12-16)18(23)7-4-8-19(24)22-17(13-26-20(22)25)14-5-2-1-3-6-14/h1-3,5-6,9-12,17-18,23H,4,7-8,13H2/t17-,18+/m1/s1

InChI key: InChIKey=AVAZNWOHQJYCEL-MSOLQXFVSA-N

SMILES: C(CCC[C@H](O)C1=CC=C(F)C=C1)(=O)N2[C@H](COC2=O)C3=CC=CC=C3

Sinonimi:

• (4S)-3-[(5R)-5-(4-Fluorophenyl)-5-Hydroxypentanoyl]-4-pheny-1,3-oxzolidin-2-One
• (4S)-3-[(5S)-5-(4-Fluoro phenyl)-5-hydroxypentanoyl]-4-phenyl-1,3-oxazolidin-2-one
• (4S)-3-[(5S)-5-(4-Fluorophenyl)-5-hydroxy-1-oxopentyl]-4-phenyl-2-oxazolidinone
• (4S)-3-[(5S)-5-(4-fluorophenyl)-5-hydroxypentanoyl]-4-phenyl-1,3-oxazolidin-2-one
• (4S)-4-Phenyl-3-[(5S)-5-(4-fluorophenyl)-5-hydroxypentanoyl]-1,3-oxazolidin-2-one
• (S)-3-((S)-5-(4-fluorophenyl)-5-hydroxypentanoyl)-4-phenyloxazolidin-2-one
• 2-Oxazolidinone, 3-[(5S)-5-(4-fluorophenyl)-5-hydroxy-1-oxopentyl]-4-phenyl-, (4S)-
• 2-Oxazolidinone, 3-[5-(4-fluorophenyl)-5-hydroxy-1-oxopentyl]-4-phenyl-, [S-(R*,R*)]-
• 3-[(5S)-(4-Fluorophenyl)-5-hydroxypentanoyl]-(4S)-phenyl-1,3-oxazolidin-2-one
• 3-[(5S)-5-(4-fluorophenyl)-5-hydroxy-1-oxopentyl]-4-phenyl-,(4S)-2-Oxazolidinone
• 3-[5-(4-Fluoro-Phenyl)-5-Hydroxy-Pentanoyl]-5-Phenyl-Oxazolidin-2-One

2-Oxazolidinone, 3-[(5S)-5-(4-fluorophenyl)-5-hydroxy-1-oxopentyl]-4-phenyl-, (4S)-

CAS: 189028-95-3

Formula: C₂₀H₂₀FNO₄

Purezza: 97%

Colore e forma: Solid

Peso molecolare: 357.3755

Ref: IN-DA002HQD

(S)-3-((S)-5-(4-Fluorophenyl)-5-Hydroxypentanoyl)-4-Phenyloxazolidin-2-One

CAS: 189028-95-3

(S)-3-((S)-5-(4-Fluorophenyl)-5-Hydroxypentanoyl)-4-Phenyloxazolidin-2-One

Purezza: 99%

Peso molecolare: 357.38g/mol

Ref: 54-PC109163

Ezetimibe Impurity 45

CAS: 189028-95-3

Formula: C₂₀H₂₀FNO₄

Colore e forma: White To Off-White Solid

Peso molecolare: 357.38

Ref: 4Z-E-0652

(S)-3-((S)-5-(4-Fluorophenyl)-5-hydroxypentanoyl)-4-phenyloxazolidin-2-one

CAS: 189028-95-3

Purezza: 95.0%

Colore e forma: Solid

Peso molecolare: 357.3810119628906

Ref: 10-F237771

3-[(5S)-(4-Fluorophenyl)-5-hydroxypentanoyl]-(4S)-phenyl-1,3-oxazolidin-2-one

Prodotto controllato

CAS: 189028-95-3

Applications 3-[(5S)-(4-Fluorophenyl)-5-hydroxypentanoyl]-(4S)-phenyl-1,3-oxazolidin-2-one is an intermediate of Ezetimibe (E975000, E975002), an antihyperlipoproteinemic. A cholesterol absorption inhibitor.
References Singh, A., et. al.: J. Molecular Catal. B., 85, 99 (2013); van Heek, M., at al.: J. Pharmacol. Exp. Ther., 283, 157 (1997); van Heek, M., at al.: Brit. J. Pharmacol., 129, 1748 (2000)

Formula: C₂₀H₂₀FNO₄

Colore e forma: Neat

Peso molecolare: 357.38

Ref: TR-F595465

Ezetimibe Impurity 16

CAS: 189028-95-3

Formula: C₂₀H₂₀FNO₄

Peso molecolare: 357.38

Ref: ST-EA-CP-E6041

(S)-3((S)-5-(4-Fluorophenyl)-5-hydroxypentanoyl)-4-phenyloxazolidin-2-one

CAS: 189028-95-3

(S)-3((S)-5-(4-Fluorophenyl)-5-hydroxypentanoyl)-4-phenyloxazolidin-2-one is an enzyme inhibitor that interrupts the biosynthesis of glucose by inhibiting the activity of the enzyme glucose dehydrogenase. This drug has been shown to be efficacious against a number of strains, including E. coli and S. typhimurium, but not other bacteria such as escherichia or mycobacteria. (S)-3((S)-5-(4-Fluorophenyl)-5-hydroxypentanoyl)-4-phenyloxazolidin-2-one is used in medicines to treat cardiovascular diseases. It has been shown to inhibit the production of dinucleotide phosphate, which is essential for the synthesis of nucleic acids and energy production in cells. The reaction system is circularly closed by this molecule.br>br>

Purezza: Min. 95%

Ref: 3D-FF57617

(S)-3-((S)-5-(4-Fluorophenyl)-5-hydroxypentanoyl)-4-phenyloxazolidin-2-one

CAS: 189028-95-3

(S)-3-((S)-5-(4-Fluorophenyl)-5-hydroxypentanoyl)-4-phenyloxazolidin-2-one is a useful organic compound for research related to life sciences. The catalog number is T66207 and the CAS number is 189028-95-3.

Formula: C₂₀H₂₀FNO₄

Colore e forma: Solid

Peso molecolare: 357.381

Ref: TM-T66207