CAS 18942-49-9

N-tert-butilossicarbonil-D-fenilalanina

Descrizione:

N-tert-butilossicarbonil-D-fenilalanina, comunemente noto come Boc-D-fenilalanina, è un derivato aminoacidico caratterizzato dalla presenza di un gruppo protettivo tert-butilossicarbonilico (Boc) attaccato al gruppo amminico della D-fenilalanina. Questo composto è tipicamente utilizzato nella sintesi di peptidi come gruppo protettivo che facilita la modifica selettiva degli aminoacidi senza interferire con altri gruppi funzionali. È un solido bianco a bianco sporco che è solubile in solventi organici come il diclorometano e il dimetilformamide, ma generalmente insolubile in acqua. Il gruppo Boc è noto per la sua stabilità in condizioni basiche e può essere facilmente rimosso in condizioni acide, rendendolo uno strumento prezioso nella sintesi organica. La presenza del gruppo fenile contribuisce alle caratteristiche idrofobiche del composto, influenzando le sue interazioni nei sistemi biologici. Come molecola chirale, esiste in due forme enantiomeriche, con la forma D utilizzata in varie applicazioni biochimiche. In generale, la Boc-D-fenilalanina è significativa nel campo della chimica medicinale e della ricerca sui peptidi.

Formula: C₁₄H₁₉NO₄

InChI: InChI=1S/C14H19NO4/c1-14(2,3)19-13(18)15-11(12(16)17)9-10-7-5-4-6-8-10/h4-8,11H,9H2,1-3H3,(H,15,18)(H,16,17)/t11-/m1/s1

InChI key: InChIKey=ZYJPUMXJBDHSIF-LLVKDONJSA-N

SMILES: [C@H](CC1=CC=CC=C1)(NC(OC(C)(C)C)=O)C(O)=O

Sinonimi:

• (2R)-2-(tert-Butoxycarbonylamino)-3-phenylpropanoic acid
• (2R)-2-[(2-Methylpropan-2-yl)oxycarbonylamino]-3-phenylpropanoic acid
• (2R)-2-[(tert-Butoxycarbonyl)amino]-3-phenylpropionic acid
• (2R)-2-[(tert-butoxycarbonyl)amino]-3-phenylpropanoate
• (2R)-2-[[(tert-Butoxy)carbonyl]amino]-3-phenylpropanoic acid
• (R)-2-((tert-Butoxycarbonyl)amino)-3-phenylpropionic acid
• (R)-2-(tert-Butoxycarbonylamino)-3-phenylpropanoic acid
• (R)-N-(tert-Butoxycarbonyl)phenylalanine
• <span class="text-smallcaps">D</span>-Phenylalanine, N-[(1,1-dimethylethoxy)carbonyl]-
• Alanine, N-carboxy-3-phenyl-, N-tert-butyl ester, <span class="text-smallcaps">D</span>-
• BOC-<span class="text-smallcaps">D</span>-phenylalanine
• Boc-D-Phe-OH
• N-(tert-Butoxycarbonyl)-D-phenylalanine
• N-BOC-<span class="text-smallcaps">D</span>-phenylalanine
• N-Boc-D-phenylalanine
• N-[(1,1-Dimethylethoxy)carbonyl]-<span class="text-smallcaps">D</span>-phenylalanine
• N-tert-Butoxycarbonyl-<span class="text-smallcaps">D</span>-phenylalanine
• N-tert-Butyloxycarbonyl-<span class="text-smallcaps">D</span>-phenylalanine
• tert-Butoxycarbonyl-<span class="text-smallcaps">D</span>-phenylalanine
• tert-Butyloxycarbonyl-<span class="text-smallcaps">D</span>-phenylalanine
• tert-Butoxycarbonyl-D-phenylalanine
• Alanine, N-carboxy-3-phenyl-, N-tert-butyl ester, D-
• D-Phenylalanine, N-[(1,1-dimethylethoxy)carbonyl]-

N-(tert-Butoxycarbonyl)-D-phenylalanine

CAS: 18942-49-9

Formula: C₁₄H₁₉NO₄

Purezza: >98.0%(T)

Colore e forma: White to Almost white powder to crystal

Peso molecolare: 265.31

Ref: 3B-B2989

N-Boc-D-phenylalanine, 98%

CAS: 18942-49-9

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Sci

Formula: C₁₄H₁₉NO₄

Purezza: 98%

Colore e forma: Crystals or powder or crystalline powder, White

Peso molecolare: 265.31

Ref: 02-L08722

Boc-D-Phe-OH

CAS: 18942-49-9

Bachem ID: 4000781.

Formula: C₁₄H₁₉NO₄

Purezza: > 99%

Colore e forma: White

Peso molecolare: 265.31

Ref: 01-4000781

Boc-D-Phe-OH

CAS: 18942-49-9

Formula: C₁₄H₁₉NO₄

Purezza: 98%

Colore e forma: Solid

Peso molecolare: 265.3050

Ref: IN-DA003OGR

Boc-D-Phe-OH

CAS: 18942-49-9

Formula: C₁₄H₁₉NO₄

Peso molecolare: 265.31

Ref: 7W-GM3541

Boc-D-phenylalanine

CAS: 18942-49-9

Boc-D-phenylalanine

Formula: C₁₄H₁₉NO₄

Purezza: 98%

Colore e forma: white to off-white powder

Peso molecolare: 265.30g/mol

Ref: 54-OR350041

Bortezomib Impurity 28

CAS: 18942-49-9

Formula: C₁₄H₁₉NO₄

Peso molecolare: 265.31

Ref: 4Z-B-4646

Boc-D-Phe-OH

CAS: 18942-49-9

Boc-D-Phe-OH is an antimicrobial peptide that is a small molecule with a molecular weight of 254.8. It has been shown to have anti-tumor activity, and can be used as an alternative to conventional chemotherapeutic drugs in the treatment of cancer. Boc-D-Phe-OH binds to the hydrophobic region on the surface of cells and disrupts the cell's membrane, causing cell death by apoptosis. This peptide also shows antibacterial activity against gramicidin S, which is a Gram-positive antibiotic that belongs to the polymyxins class. The antibacterial activity of this peptide may be due to its ability to bind to divalent cations such as calcium ions and magnesium ions. Boc-D-Phe-OH has been synthesized using a method that is both efficient and rapid (less than 12 hours). It has also been shown that this peptide does not show any

Formula: C₁₄H₁₉NO₄

Purezza: Min. 95%

Peso molecolare: 265.3 g/mol

Ref: 3D-BDF-2604

Boc-D-Phe-OH

CAS: 18942-49-9

M03311 - Boc-D-Phe-OH

Formula: C₁₄H₁₉NO₄

Purezza: 98%

Colore e forma: Solid, Crystalline Powder or Powder

Peso molecolare: 265.309

Ref: 10-M03311

N-Boc-D-phenylalanine

CAS: 18942-49-9

D-Phenylalanine is a molecule that is used in the synthesis of peptidomimetics. It has been shown to have a high efficiency method in the synthesis of N-Boc-D-phenylalanine, which can be used as a glycosidic bond precursor. This chemical has been shown to have anti-tumor properties and it may be useful in binding experiments with ferrocene. The compound can also form hydrogen bonds with acids, such as the acid catalyst found in the digestive system.

Formula: C₁₄H₁₉NO₄

Purezza: Min. 95%

Colore e forma: Powder

Peso molecolare: 265.31 g/mol

Ref: 3D-FB37462

BOC-D-Phenylalanine extrapure, 99%

CAS: 18942-49-9

Formula: C₁₄H₁₉NO₄

Purezza: min. 99%

Colore e forma: White, Powder

Peso molecolare: 265.30

Ref: SR-40474

Boc-D-Phenylalanine

Prodotto controllato

CAS: 18942-49-9

Applications Boc-D-Phenylalanine is used in the synthesis of benzo[de][1,7]napthyridinones as PARP1 inhibitors. Also it is an important reagent in the preparation of proline-containing, β-turn mimetic cycle tetrapeptides.
References Ye, Na. et al.: J. Med. Chem., 56, 2885 (2013); Chouhan, G. et al.: Org. Lett., 15, 1206 (2013);

Formula: C₁₄H₁₉NO₄

Colore e forma: Neat

Peso molecolare: 265.3

Ref: TR-B661525

Bortezomib Impurity 28

CAS: 18942-49-9

Formula: C₁₄H₁₉NO₄

Peso molecolare: 265.3

Ref: ST-EA-CP-B34041