CAS 19057-60-4

(+)-Dioscina

Descrizione:

(+)-Dioscina, con il numero CAS 19057-60-4, è una saponina esteroidea di origine naturale estratta principalmente da varie fonti vegetali, in particolare dal genere Dioscorea, comunemente noto come igname. Questo composto è caratterizzato dalla sua complessa struttura glicosidica, che include uno scheletro steroideo legato a moieties di zucchero. (+)-Dioscina mostra una gamma di attività biologiche, comprese proprietà anti-infiammatorie, antiossidanti e potenziali proprietà anticancro, rendendolo di interesse nella ricerca farmacologica. La sua solubilità è generalmente bassa in acqua, ma può dissolversi in solventi organici, il che è tipico per molte saponine. La struttura del composto contribuisce alla sua capacità di interagire con le membrane cellulari, influenzando i processi cellulari. Inoltre, (+)-Dioscina è stato studiato per i suoi potenziali effetti sul metabolismo del colesterolo e il suo ruolo nella medicina tradizionale. Come per molti prodotti naturali, i processi di estrazione e purificazione possono influenzare significativamente la sua bioattività e efficacia, evidenziando l'importanza dei metodi di approvvigionamento e preparazione nella ricerca e applicazione.

Formula: C₄₅H₇₂O₁₆

InChI: InChI=1/C45H72O16/c1-19-9-14-45(54-18-19)20(2)30-28(61-45)16-27-25-8-7-23-15-24(10-12-43(23,5)26(25)11-13-44(27,30)6)57-42-39(60-41-36(52)34(50)32(48)22(4)56-41)37(53)38(29(17-46)58-42)59-40-35(51)33(49)31(47)21(3)55-40/h7,19-22,24-42,46-53H,8-18H2,1-6H3/t19-,20+,21+,22+,24+,25-,26+,27?,28+,29-,30+,31+,32+,33-,34-,35-,36-,37+,38-,39-,40+,41+,42-,43+,44+,45-/m1/s1

InChI key: InChIKey=VNONINPVFQTJOC-ZGXDEBHDSA-N

SMILES: C[C@@]12[C@@]3([C@](C[C@]1([C@]4([C@](CC2)([C@]5(C)C(=CC4)C[C@@H](O[C@H]6[C@H](O[C@H]7[C@H](O)[C@H](O)[C@@H](O)[C@H](C)O7)[C@@H](O)[C@H](O[C@H]8[C@H](O)[C@H](O)[C@@H](O)[C@H](C)O8)[C@@H](CO)O6)CC5)[H])[H])[H])(O[C@@]9([C@H]3C)CC[C@@H](C)CO9)[H])[H]

Sinonimi:

• (3beta,14xi,25R)-spirost-5-en-3-yl 6-deoxy-alpha-L-mannopyranosyl-(1->2)-[6-deoxy-alpha-L-mannopyranosyl-(1->4)]-beta-D-glucopyranoside
• (3beta,25R)-spirost-5-en-3-yl 6-deoxy-alpha-L-mannopyranosyl-(1->2)-[6-deoxy-alpha-L-mannopyranosyl-(1->4)]-beta-D-glucopyranoside
• (3β,25R)-Spirost-5-en-3-yl O-6-deoxy-α-<span class="text-smallcaps">L</smallcap>-mannopyranosyl-(1→2)-O-[6-deoxy-α-<smallcap>L</smallcap>-mannopyranosyl-(1→4)]-β-<smallcap>D</span>-glucopyranoside
• 3-O-β-<span class="text-smallcaps">D</smallcap>-α-<smallcap>L</smallcap>-Rhamnopyranosyl(1→4)-[α-<smallcap>L</smallcap>-rhamnopyranosyl(1→2)]-β-<smallcap>D</span>-glucopyranoside-diosgenin
• Beta-D-Glucopyranoside,(3-Beta,25R)-Spirost-5-En-3-Ylo-6-Deoxy-Alpha-L-Mannop
• Collettiside III
• Collettisideiii
• Dioscin(P)
• Dioscine
• Diosgenin 3-O-α-<span class="text-smallcaps">L</smallcap>-rhamnopyranosyl-(1→2)-[α-<smallcap>L</smallcap>-rhamnopyranosyl-(1→4)]-β-<smallcap>D</span>-glucopyranoside
• Diosgenin 3-O-α-<span class="text-smallcaps">L</smallcap>-rhamnopyranosyl-(1→4)-[α-<smallcap>L</smallcap>-rhamnopyranosyl-(1→2)]-β-<smallcap>D</span>-glucopyranoside
• Diosgenin bis-α-<span class="text-smallcaps">L</smallcap>-rhamnopyranosyl-(1→2 and 1→4)-β-<smallcap>D</span>-glucopyranoside
• Paris III
• Parissaponin III
• Polyphyllin III
• Yranosyl-(1-2)-O-(6-Deoxy-Alpha-L-Mannopyranosyl)-(1-4))-
• β-<span class="text-smallcaps">D</smallcap>-Glucopyranoside, (3β,25R)-spirost-5-en-3-yl O-6-deoxy-α-<smallcap>L</smallcap>-mannopyranosyl-(1→2)-O-[6-deoxy-α-<smallcap>L</span>-mannopyranosyl-(1→4)]-
• β-D-Glucopyranoside, (3β,25R)-spirost-5-en-3-yl O-6-deoxy-α-L-mannopyranosyl-(1→2)-O-[6-deoxy-α-L-mannopyranosyl-(1→4)]-
• Dioscin
• Diosgenin bis-α-L-rhamnopyranosyl-(1→2 and 1→4)-β-D-glucopyranoside
• (3β,25R)-Spirost-5-en-3-yl O-6-deoxy-α-L-mannopyranosyl-(1→2)-O-[6-deoxy-α-L-mannopyranosyl-(1→4)]-β-D-glucopyranoside
• [(25R)-Spirosta-5-ene-3β-yl]2-O,4-O-bis(α-L-rhamnopyranosyl)-β-D-glucopyranoside
• (25R)-3β-[2-O,4-O-Bis(α-L-rhamnopyranosyl)-β-D-glucopyranosyloxy]spirosta-5-ene
• Dioscin Green Plants Extracts 19057-60-4 Dioscorea Nipponica Source
• Dioscin / Diosgenyl 2,4-Di-O-α-L-rhamnopyranosyl-β-D-glucopyranoside
• Diosgenin bis-alpha-L-rhamnopyranosyl)-(1-2 and 1-4)-beta-D-glucopyranoside
• Dioscin(Collettiside III)
• DIOSCIN(RG)
• Ccris 4123
• Dioscin 19057-60-4
• beta-D-Glucopyranoside, (3beta,25R)-spirost-5-en-3-yl o-6-deoxy-alpha-L-mannopyranosyl-(1-2)-o-(6-deoxy-alpha-L-mannopyranosyl-(1-4))-
• Dioscin (6ci,7ci,8ci)
• [(25R)-Spirosta-5-ene-3β-yl]2-O,4-O-di-α-L-rhamnopyranosyl-β-D-glucopyranoside
• Dioscin, 98%, from Dioscorea opposita Thunb.
• Yam Extract Dioscin
• Dioscin USP/EP/BP
• ioscin
• [(25R)-Spirost-5-en-3β-yl]2-O-(6-deoxy-α-L-mannopyranosyl)-4-O-(6-deoxy-α-L-mannopyranosyl)-β-D-glucopyranoside

Dioscin

CAS: 19057-60-4

Formula: C₄₅H₇₂O₁₆

Purezza: >95.0%(HPLC)

Colore e forma: White to Light yellow powder to crystal

Peso molecolare: 869.06

Ref: 3B-D5167

Dioscin

CAS: 19057-60-4

Dioscin analytical standard provided with w/w absolute assay, to be used for quantitative titration.

Formula: C₄₅H₇₂O₁₆

Purezza: (HPLC) ≥98%

Colore e forma: Powder

Peso molecolare: 869.06

Ref: 11-3515S

Dioscin

CAS: 19057-60-4

Formula: C₄₅H₇₂O₁₆

Purezza: 95%

Colore e forma: Solid

Peso molecolare: 869.0436

Ref: IN-DA00I2TD

Dioscin

CAS: 19057-60-4

Dioscin

Purezza: ≥98%

Peso molecolare: 869.04g/mol

Ref: 54-BUP00105

Dioscin

CAS: 19057-60-4

Dioscin

Purezza: 98%

Peso molecolare: 869.04g/mol

Ref: 54-OR1026166

Dioscin

CAS: 19057-60-4

Dioscin, a saponin extracted from the root of Polygonatum Zanlanscianense Pamp, can markedly inhibit proliferation of Hela cells, underwent apoptosis in dose- and time-dependent manner.

Formula: C₄₅H₇₂O₁₆

Purezza: 95%~99%

Colore e forma: Powder

Peso molecolare: 869.055

Ref: BP-BP0503

Dioscin

CAS: 19057-60-4

Ref: 7W-GC9259

Dioscin

CAS: 19057-60-4

Dioscin (Collettiside III) is a saponin with antitumor activities.

Formula: C₄₅H₇₂O₁₆

Purezza: 99.85% - 99.87%

Colore e forma: Solid

Peso molecolare: 869.04

Ref: TM-T6473

Dioscin

CAS: 19057-60-4

Formula: C₄₅H₇₂O₁₆

Peso molecolare: 869.06

Ref: 4Z-G-157006

Dioscin

CAS: 19057-60-4

Natural glycoside

Formula: C₄₅H₇₂O₁₆

Purezza: ≥ 90.0 % (HPLC)

Colore e forma: Powder

Peso molecolare: 869.06

Ref: 5G-89648

Dioscin

CAS: 19057-60-4

Applications Dioscin, a natural steroid saponin that has been shown to promote anticancer activity against several forms of cancers. Dioscin induces cancer cell apoptosis through elevated oxidative stress mediated by downregulation of peroxiredoxins.
References Wang, Z., et al.: Land. Biosci., 13, 138 (2012); Shah, H.J., et al.: J. Anal. BIoanal. Tech., 3, 141 (2012); Zhao, X.M., et al.: Toxiciol. Lett., 214, 69 (2012);

Formula: C₄₅H₇₂O₁₆

Colore e forma: Neat

Peso molecolare: 869.04

Ref: TR-D485230

Dioscin

CAS: 19057-60-4

Dioscin is a steroidal saponin, which is a naturally occurring compound found in various plants, notably in species such as Dioscorea nipponica and Dioscorea zingiberensis. These plants belong to the yam family, which are well-regarded for their medicinal properties. The mode of action of dioscin involves modulation of various biochemical pathways, including the suppression of inflammatory cytokines and inhibition of cancer cell proliferation. Additionally, dioscin has been shown to promote apoptosis in cancer cells through the activation of caspases and disruption of mitochondrial function.

Formula: C₄₅H₇₂O₁₆

Purezza: Min. 95%

Colore e forma: Powder

Peso molecolare: 869.05 g/mol

Ref: 3D-OD11563

Dioscin

CAS: 19057-60-4

Dioscin is a type of steroidal saponin, which is a naturally occurring glycoside. It is primarily derived from various plant sources, including members of the Dioscorea family, such as wild yam species. Dioscin exhibits its biological activity through modulation of multiple molecular pathways, notably exhibiting anti-inflammatory, antioxidative, and antiproliferative effects.

Formula: C₄₅H₇₂O₁₆

Purezza: Min. 98.0 Area-%

Peso molecolare: 869.04 g/mol

Ref: 3D-Q-100228