CAS 19121-58-5

Solasonina

Descrizione:

Solasonina è un glicoalcaloide trovato principalmente in alcune specie della famiglia Solanaceae, in particolare in piante come la patata amara e alcune varietà di melanzana. È caratterizzato dalla sua struttura complessa, che include uno scheletro steroideo e una porzione di zucchero, tipicamente legata a un atomo di azoto. Solasonina mostra una gamma di attività biologiche, comprese potenziali proprietà antifungine e insetticide, che contribuiscono ai meccanismi di difesa della pianta. Tuttavia, è anche noto per la sua tossicità, poiché alte concentrazioni possono portare a effetti avversi sulla salute in esseri umani e animali, inclusi disturbi gastrointestinali e sintomi neurologici. Il composto è solubile in alcol e leggermente solubile in acqua, il che influisce sulla sua estrazione e analisi in ambienti di laboratorio. A causa della sua natura tossica, Solasonina è di interesse sia nella ricerca farmacologica che nelle valutazioni di sicurezza alimentare, richiedendo una manipolazione e uno studio accurati per comprendere i suoi effetti e le potenziali applicazioni.

Formula: C₄₅H₇₃NO₁₆

InChI: InChI=1/C45H73NO16/c1-19-8-13-45(46-16-19)20(2)30-27(62-45)15-26-24-7-6-22-14-23(9-11-43(22,4)25(24)10-12-44(26,30)5)57-42-39(61-40-36(54)34(52)31(49)21(3)56-40)38(33(51)29(18-48)59-42)60-41-37(55)35(53)32(50)28(17-47)58-41/h6,19-21,23-42,46-55H,7-18H2,1-5H3/t19-,20+,21+,23+,24-,25+,26+,27+,28-,29-,30+,31+,32-,33+,34-,35+,36-,37-,38+,39-,40+,41+,42-,43+,44+,45-/m1/s1

InChI key: InChIKey=QCTMYNGDIBTNSK-XEAAVONHSA-N

SMILES: C[C@@]12[C@@]3([C@](C[C@]1([C@]4([C@](CC2)([C@]5(C)C(=CC4)C[C@@H](O[C@H]6[C@H](O[C@H]7[C@H](O)[C@H](O)[C@@H](O)[C@H](C)O7)[C@@H](O[C@@H]8O[C@H](CO)[C@@H](O)[C@H](O)[C@H]8O)[C@@H](O)[C@@H](CO)O6)CC5)[H])[H])[H])(O[C@@]9([C@H]3C)CC[C@@H](C)CN9)[H])[H]

Sinonimi:

• (3beta,22alpha,25R)-spirosol-5-en-3-yl 6-deoxy-alpha-L-mannopyranosyl-(1->2)-[beta-D-glucopyranosyl-(1->3)]-beta-D-galactopyranoside
• (3beta,22alpha,25S)-spirosol-5-en-3-yl 6-deoxy-alpha-L-mannopyranosyl-(1->2)-[beta-D-glucopyranosyl-(1->3)]-beta-D-galactopyranoside
• (3beta,22alpha,25S)-spirosol-5-en-3-yl 6-deoxyhexopyranosyl-(1->2)-[hexopyranosyl-(1->3)]hexopyranoside
• (3β,22α,25R)-Spirosol-5-en-3-yl O-6-deoxy-α-<span class="text-smallcaps">L</smallcap>-mannopyranosyl-(1→2)-O-[β-<smallcap>D</smallcap>-glucopyranosyl-(1→3)]-β-<smallcap>D</span>-galactopyranoside
• Nsc 82149
• Solasonin
• Spirosolane, β-<span class="text-smallcaps">D</span>-galactopyranoside deriv.
• Tomatine solaradixine
• alpha-Solasonine
• beta-D-Galactopyranoside, (3beta,22alpha,25R)-spirosol-5-en-3-yl O-6-deoxy-alpha-L-mannopyranosyl-(1-2)-O-(beta-D-glucopyranosyl-(1-3))-
• α-Solasonine
• β-<span class="text-smallcaps">D</smallcap>-Galactopyranoside, (3β,22α,25R)-spirosol-5-en-3-yl O-6-deoxy-α-<smallcap>L</smallcap>-mannopyranosyl-(1→2)-O-[β-<smallcap>D</span>-glucopyranosyl-(1→3)]-
• β-D-Galactopyranoside, (3β,22α,25R)-spirosol-5-en-3-yl O-6-deoxy-α-L-mannopyranosyl-(1→2)-O-[β-D-glucopyranosyl-(1→3)]-
• Spirosolane, β-D-galactopyranoside deriv.
• Solasonine
• (3β,22α,25R)-Spirosol-5-en-3-yl O-6-deoxy-α-L-mannopyranosyl-(1→2)-O-[β-D-glucopyranosyl-(1→3)]-β-D-galactopyranoside
• SOLANINE S
• SOLASODAMINE
• [(22R,25R)-Spirosol-5-en-3β-yl]2-O-(6-deoxy-α-L-mannopyranosyl)-3-O-(β-D-glucopyranosyl)-β-D-galactopyranoside
• SOLASONINE(RG)
• Solasonine 19121-58-5
• PURAPURINE
• 5-SOLASODEN-3BETA-OL 3-O-6-D-DEOXY-ALPHA-L-MONOPYRANOSYL (1->2)-BETA-D-GLUCOPYRANOSYL (1->3)-BETA-D-GALACTOPYRANOSIDE
• .beta.-D-Galactopyranoside, (3.beta.,22.alpha.,25R)-spirosol-5-en-3-yl O-6-deoxy-.alpha.-L-mannopyranosyl-(1?2)-O-.beta.-D-glucopyranosyl-(1?3)-
• (2S,3R,4S,5S,6R)-2-(((2R,3S,4S,5R,6R)-3-hydroxy-2-(hydroxymethyl)-6-(((2'S,4S,5'R,6aR,6bS,8aS,8bR,9S,11aS,12aS,12bS)-5',6a,8a,9-tetramethyl-1,3,4,5,6,6a,6b,7,8,8a,8b,9,11a,12,12a,12b-hexadecahydrospiro[naphtho[2',1':4,5]indeno[2,1-b]furan-10,2'-piperidin]-4-yl)oxy)-5-(((2R,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)tetrahydro-2H-pyran-4-yl)oxy)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol
• SOLANCARPIN
• Solasoonine

α-Solasonine

CAS: 19121-58-5

alpha-Solasonine analytical standard provided with w/w absolute assay, to be used for quantitative titration.

Formula: C₄₅H₇₃NO₁₆

Purezza: (HPLC) ≥98%

Colore e forma: Powder

Peso molecolare: 884.08

Ref: 11-1658S

β-D-Galactopyranoside, (3β,22α,25R)-spirosol-5-en-3-yl O-6-deoxy-α-L-mannopyranosyl-(1→2)-O-[β-D-glucopyranosyl-(1→3)]-

CAS: 19121-58-5

Formula: C₄₅H₇₃NO₁₆

Purezza: 98%

Peso molecolare: 884.0582

Ref: IN-DA002F3Y

Solasonine

CAS: 19121-58-5

Formula: C₄₅H₇₃NO₁₆

Purezza: ≥ 98.0%

Colore e forma: White to off-white solid

Peso molecolare: 884.06

Ref: 7W-GP5592

Solasonine

CAS: 19121-58-5

Solasonine

Purezza: ≥98%

Peso molecolare: 884.06g/mol

Ref: 54-BUP00772

Solasonine

CAS: 19121-58-5

Solasonine displays leishmanicidal activity against promastigote forms of L. amazonensis.

Formula: C₄₅H₇₃NO₁₆

Purezza: 95%~99%

Peso molecolare: 884.07

Ref: BP-BP1323

Solasonine

CAS: 19121-58-5

Solasonine exerts leishmanicidal activity against promastigote forms of L. amazonensis.

Formula: C₄₅H₇₃NO₁₆

Purezza: 98% - 99.8%

Colore e forma: Solid

Peso molecolare: 884.06

Ref: TM-T3901

Α-solasonine

CAS: 19121-58-5

Natural alkaloid

Formula: C₄₅H₇₃NO₁₆

Purezza: ≥ 90.0 % (HPLC)

Colore e forma: Powder

Peso molecolare: 884.07

Ref: 5G-83271

Solasonine

CAS: 19121-58-5

Solasonine is a cytotoxic glycoalkaloid found in plants of the genus Solanum. This steroidal glucoside has anti-proliferative activity and can trigger apoptosis. In breast cancer cell lines, it activates the mitochondrial cytochrome c-mediated pathway. In a liver cancer in vitro model, solasonine inhibits interactions between mortalin, a Hsp70 chaperone, and tumor suppressor p53, allowing p53 to activate the cell death pathway.

Formula: C₄₅H₇₃NO₁₆

Purezza: Min. 95%

Colore e forma: White Powder

Peso molecolare: 884.06 g/mol

Ref: 3D-OS65589

Solasonine extrapure, 98%

CAS: 19121-58-5

Formula: C₄₅H₇₃NO₁₆

Purezza: min. 98.0%

Colore e forma: White to off-white to beige, Powder

Peso molecolare: 884.06

Ref: SR-89725