CAS 19309-14-9

Cardamonina

Descrizione:

Cardamonina è un composto che si verifica naturalmente classificato come una chalcone, derivato principalmente dai semi della pianta Elettaria cardamomum, comunemente nota come cardamomo. È caratterizzato dalla sua apparente cristallina gialla e ha una formula molecolare che riflette la sua struttura complessa. Cardamonina mostra varie attività biologiche, comprese proprietà anti-infiammatorie, antiossidanti e antimicrobiche, rendendolo di interesse nella ricerca farmacologica. Il suo meccanismo d'azione spesso implica la modulazione delle vie di segnalazione, che possono influenzare la proliferazione cellulare e l'apoptosi. Inoltre, Cardamonina è stato studiato per i suoi potenziali effetti terapeutici in condizioni come il cancro e i disturbi metabolici. Il composto è solubile in solventi organici ma ha una solubilità limitata in acqua, il che può influenzare la sua biodisponibilità. In generale, Cardamonina rappresenta un'area significativa di interesse nella chimica dei prodotti naturali e nella ricerca medicinale grazie alle sue diverse attività biologiche e potenziali benefici per la salute.

Formula: C₁₆H₁₄O₄

InChI: InChI=1S/C16H14O4/c1-20-15-10-12(17)9-14(19)16(15)13(18)8-7-11-5-3-2-4-6-11/h2-10,17,19H,1H3/b8-7+

InChI key: InChIKey=NYSZJNUIVUBQMM-BQYQJAHWSA-N

SMILES: C(/C=C/C1=CC=CC=C1)(=O)C2=C(OC)C=C(O)C=C2O

Sinonimi:

• (2E)-1-(2,4-Dihydroxy-6-methoxyphenyl)-3-phenyl-2-propen-1-one
• (2E)-1-(2,4-dihydroxy-6-methoxyphenyl)-3-phenylprop-2-en-1-one
• (E)-1-(2,4-Dihydroxy-6-Methoxy-Phenyl)-3-Phenyl-Propenone
• (E)-1-(2,4-Dihydroxy-6-methoxy-phenyl)-3-phenyl-
• 2-Propen-1-one, 1-(2,4-dihydroxy-6-methoxyphenyl)-3-phenyl-, (2E)-
• 2-Propen-1-one, 1-(2,4-dihydroxy-6-methoxyphenyl)-3-phenyl-, (E)-
• Alpinetin chalcone
• Cardamomin
• Chalcone, 2', 4'-dihydroxy-6'-methoxy-
• Chalcone, 2′,4′-dihydroxy-6′-methoxy-
• Cardamonin

(E)-Cardamonin

CAS: 19309-14-9

(E)-Cardamonin (Alpinetin chalcone) is a chalconoid that has been isolated from several plants including Alpinia katsumadai and Alpinia conchigera.

Formula: C₁₆H₁₄O₄

Purezza: 99.07% - 99.84%

Colore e forma: Solid

Peso molecolare: 270.28

Ref: TM-T2994

Cardamonin

CAS: 19309-14-9

Formula: C₁₆H₁₄O₄

Purezza: 98%

Colore e forma: Solid

Peso molecolare: 270.2800

Ref: IN-DA00AOR0

(E)-1-(2,4-Dihydroxy-6-Methoxyphenyl)-3-Phenylprop-2-En-1-One

CAS: 19309-14-9

(E)-1-(2,4-Dihydroxy-6-Methoxyphenyl)-3-Phenylprop-2-En-1-One

Purezza: 99%

Peso molecolare: 270.28g/mol

Ref: 54-OR1008324

(E)-Cardamonin

CAS: 19309-14-9

(E)-Cardamonin

Purezza: ≥98%

Peso molecolare: 270.28g/mol

Ref: 54-BUP11154

Cardamonin

CAS: 19309-14-9

Cardamonin is a naturally occurring chalcone with strong anti-inflammatory , anticancer, anti-melanogenesis, and vascular activity. It is a novel TRPA1 antagonist with IC50 of 454 nM and also a NF-kB inhibitor. It ameliorates insulin resistance induced by high insulin and high glucose through the mTOR and signal pathway. It also may be a potential whitening agent for use in cosmetics and in the medical treatment of hyperpigmentation disorders.

Formula: C₁₆H₁₄O₄

Purezza: 95%~99%

Peso molecolare: 270.284

Ref: BP-BP0315

Cardamonin

CAS: 19309-14-9

Formula: C₁₆H₁₄O₄

Purezza: ≥ 98.0%

Colore e forma: Yellow powder

Peso molecolare: 270.28

Ref: 7W-GK9563

Cardamomin

CAS: 19309-14-9

Ketone phenol

Formula: C₁₆H₁₄O₄

Purezza: ≥ 98.0 % (HPLC)

Colore e forma: Powder

Peso molecolare: 270.29

Ref: 5G-80379

Cardamonin

CAS: 19309-14-9

Cardamonin is a natural chalcone, which is a type of aromatic ketone and an unsaturated polyphenolic compound. It is primarily sourced from various plants, particularly from the seeds of Alpinia katsumadai, a member of the Zingiberaceae family. Its mode of action involves modulation of multiple cellular pathways, including inhibition of NF-κB activation, which plays a critical role in inflammatory responses and cancer cell proliferation. Additionally, cardamonin has been shown to interfere with other signaling pathways like MAPK and PI3K/Akt, which are key in regulating cell growth and survival.

Formula: C₁₆H₁₄O₄

Purezza: Min. 95%

Colore e forma: Yellow Powder

Peso molecolare: 270.28 g/mol

Ref: 3D-FC66017

Cardamonin

CAS: 19309-14-9

Applications Cardamonin maintains inhibitory effects of cardamonin on thromboxane A2-induced scratching response in mice. Also inhibits angiotensin II-induced vascular smooth muscle cell proliferation.
References Park, M. et al.: Pharm. Biochem. Behav., 126, 131 (2014); Shen, Y. et al.: J. Nat. Med., 68, 623 (2014);

Formula: C₁₆H₁₄O₄

Colore e forma: Off White Solid

Peso molecolare: 270.28

Ref: TR-C183380