CAS 19396-06-6

Poliossina B

Descrizione:

Poliossina B è un composto antifungino naturale prodotto dalla fermentazione di alcune specie di Streptomyces, in particolare Streptomyces griseus. È classificato come un antibiotico nucleosidico ed è principalmente noto per la sua capacità di inibire la sintesi della chitina, un componente critico delle pareti cellulari fungine. Questo meccanismo d'azione rende Poliossina B efficace contro una varietà di patogeni fungini, in particolare in contesti agricoli dove viene utilizzato come biopesticida. Il composto presenta un ampio spettro di attività antifungina, mirando a funghi come le specie di Fusarium e Rhizoctonia. Poliossina B è caratterizzato dalla sua tossicità relativamente bassa per i mammiferi, il che lo rende un'alternativa più sicura ai fungicidi sintetici. Inoltre, è solubile in acqua, consentendo un'applicazione facile in varie formulazioni. Il suo utilizzo è particolarmente apprezzato nell'agricoltura biologica grazie alla sua origine naturale e al minimo impatto ambientale. In generale, Poliossina B rappresenta uno strumento importante nella gestione delle malattie fungine nelle colture, promuovendo pratiche agricole sostenibili.

Formula: C₁₇H₂₅N₅O₁₃

InChI: InChI=1S/C17H25N5O13/c18-6(8(25)5(24)3-34-16(19)32)13(29)20-7(15(30)31)11-9(26)10(27)14(35-11)22-1-4(2-23)12(28)21-17(22)33/h1,5-11,14,23-27H,2-3,18H2,(H2,19,32)(H,20,29)(H,30,31)(H,21,28,33)/t5-,6-,7-,8+,9-,10+,11+,14+/m0/s1

InChI key: InChIKey=YFZNSPMAOIVQRP-YVKGXWRCSA-N

SMILES: O[C@H]1[C@@H](O[C@]([C@H](NC([C@H]([C@@H]([C@H](COC(N)=O)O)O)N)=O)C(O)=O)([C@H]1O)[H])N2C=C(CO)C(=O)NC2=O

Sinonimi:

• (2S)-{[(2S,3S,4S)-2-amino-5-(carbamoyloxy)-3,4-dihydroxypentanoyl]amino}{(2R,3S,4R,5R)-3,4-dihydroxy-5-[5-(hydroxymethyl)-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl]tetrahydrofuran-2-yl}ethanoic acid (non-preferred name)
• (2S)-{[(2S,3S,4S)-2-amino-5-(carbamoyloxy)-3,4-dihydroxypentanoyl]amino}{(2R,5R)-3,4-dihydroxy-5-[5-(hydroxymethyl)-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl]tetrahydrofuran-2-yl}ethanoic acid (non-preferred name)
• 5-(2-Amino-5-O-carbamoyl-2-deoxy-L-xylonamido)-1,5-dideoxy-1-(3,4-dihydro-5-hydroxymethyl-2,4-dioxo-1(2H)-pyrimidinyl)-beta-D-allofuranuronic acid
• 5-[[2-Amino-5-O-(aminocarbonyl)-2-deoxy-<span class="text-smallcaps">L</smallcap>-xylonoyl]amino]-1,5-dideoxy-1-[3,4-dihydro-5-(hydroxymethyl)-2,4-dioxo-1(2H)-pyrimidinyl]-β-<smallcap>D</span>-allofuranuronic acid
• Allofuranuronic acid, 5-(2-amino-2-deoxy-<span class="text-smallcaps">L</smallcap>-xylonamido)-1,5-dideoxy-1-[3,4-dihydro-5-(hydroxymethyl)-2,4-dioxo-1(2H)-pyrimidinyl]-, monocarbamate (ester), β-<smallcap>D</span>-
• Allofuranuronic acid, 5-(2-amino-2-deoxy-L-xylonamido)-1,5-dideoxy-1-(3,4-dihydro-5-(hydroxymethyl)-2,4-dioxo-1(2H)-pyrimidinyl)-, monocarbamate (ester), beta-D-
• Duoyangqing
• Milpan
• Polar
• Polar (antibiotic)
• Polyoxin AL
• Polyoxin B
• Polyoxin B 34% Tk
• {[2-amino-5-(carbamoyloxy)-3,4-dihydroxypentanoyl]amino}{3,4-dihydroxy-5-[5-(hydroxymethyl)-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl]tetrahydrofuran-2-yl}acetic acid (non-preferred name)
• β-<span class="text-smallcaps">D</smallcap>-Allofuranuronic acid, 5-[[2-amino-5-O-(aminocarbonyl)-2-deoxy-<smallcap>L</span>-xylonoyl]amino]-1,5-dideoxy-1-[3,4-dihydro-5-(hydroxymethyl)-2,4-dioxo-1(2H)-pyrimidinyl]-
• Allofuranuronic acid, 5-(2-amino-2-deoxy-L-xylonamido)-1,5-dideoxy-1-[3,4-dihydro-5-(hydroxymethyl)-2,4-dioxo-1(2H)-pyrimidinyl]-, monocarbamate (ester), β-D-
• 5-[[2-Amino-5-O-(aminocarbonyl)-2-deoxy-L-xylonoyl]amino]-1,5-dideoxy-1-[3,4-dihydro-5-(hydroxymethyl)-2,4-dioxo-1(2H)-pyrimidinyl]-β-D-allofuranuronic acid
• β-D-Allofuranuronic acid, 5-[[2-amino-5-O-(aminocarbonyl)-2-deoxy-L-xylonoyl]amino]-1,5-dideoxy-1-[3,4-dihydro-5-(hydroxymethyl)-2,4-dioxo-1(2H)-pyrimidinyl]-
• 5-(2-amino-5-o-carbamoyl-2-deoxy-l-xylonamido-1,5-dideoxy-1-(3,4-dihydro-5-hydroxymethyl-2,4-dioxo-1-(2h)-pyrimidinyl)-beta-d-allofuranuronicacid
• 5-[[2-Amino-5-O-(aminocarbonyl)-2-deoxy-L-xylonoyl]amino]-1,5-dideoxy-1-[3,4-dihydro-5-(hydroxymethyl)-2,4-dioxopyrimidin-1(2H)-yl]-β-D-allofuranuronic acid
• 5-[[2-amino-5-o-(aminocarbonyl)-2-deoxy-l-xylonoyl]amino]-1,5-dideoxy-1-[3,4-dihydro-5-(hydroxymeth.beta.-d-Allofuranuronicacid
• ro-5-(hydroxymethyl)-2,4-dioxo-1(2h)-pyrimidinyl)-,monocarbamate(ester),bet
• polyoxin AL(JMAF)
• polyoxinal
• 5-[(2-Amino-5-O-carbamoyl-2-deoxy-L-xylonoyl)amino]-1,5-dideoxy-1-[3,4-dihydro-5-(hydroxymethyl)-2,4-dioxopyrimidin-1(2H)-yl]-β-D-allofuranuronic acid
• 5-[2-Amino-5-O-(aminocarbonyl)-2-deoxy-L-xylos-1-ylamino]-1-(3,4-dihydro-5-hydroxymethyl-2,4-dioxopyrimidin-1(2H)-yl)-1,5-dideoxy-β-D-allofuranuronic acid
• 5-[[2-amino-5-o-(aminocarbonyl)-2-deoxy-l-xylonoyl]amino]-1,5-dideoxy-1-[3,4-dihydro-5-(hydroxymeth.beta.-d-Allofuranuronic acid
• allofuranuronicacid,5-(2-amino-2-deoxy-l-xylonamido)-1,5-dideoxy-1-(3,4-dihyd
• 5-{[2-amino-5-O-(aminocarbonyl)-2-deoxy-L-xylonoyl] amino}-1,5-dideoxy-1-[3,4-dihydro-5-(hydroxymethyl)-2,4-dioxo-1(2H)-pyrimnidinyl]-β-D-allofur-a-nuronic acid
• POLYXIN

b-D-Allofuranuronic acid,5-[[2-amino-5-O-(aminocarbonyl)-2-deoxy-L-xylonoyl]amino]-1,5-dideoxy-1-[3,4-dihydro-5-(hydroxymethyl)-2,4-dioxo-1(2H)-pyrimidinyl]-

CAS: 19396-06-6

Formula: C₁₇H₂₅N₅O₁₃

Purezza: 70%

Colore e forma: Solid

Peso molecolare: 507.4061

Ref: IN-DA00I31H

Polyoxin b

CAS: 19396-06-6

Polyoxin b

Formula: C₁₇H₂₅N₅O₁₃

Purezza: ≥95%

Colore e forma: solid

Peso molecolare: 507.41g/mol

Ref: 54-OR927861

Polyoxin B

CAS: 19396-06-6

Polyoxin B

Purezza: ≥70%

Peso molecolare: 507.41g/mol

Ref: 54-BUP03267

Polyoxin B

CAS: 19396-06-6

Formula: C₁₇H₂₅N₅O₁₃

Peso molecolare: 507.41

Ref: 4Z-P-288002

Polyoxin B

CAS: 19396-06-6

Polyoxin B is an antifungal peptidyl nucleoside antibiotic that inhibits fungal cell wall biosynthesis.

Formula: C₁₇H₂₅N₅O₁₃

Purezza: 79.94%

Colore e forma: Solid

Peso molecolare: 507.41

Ref: TM-T28436

Polyoxin B

CAS: 19396-06-6

Polyoxin B is a natural product that is produced by the fungus Polyporus umbellatus. It is a synthetase inhibitor that specifically inhibits the enzyme malic acid synthetase in bacteria and fungi. Polyoxin B has been shown to have antifungal activity in vitro and to inhibit the growth of Cryptococcus neoformans, which may be due to its ability to inhibit terminal residues, such as acetate extract, bacterial strain, and synthase enzyme.

Formula: C₁₇H₂₅N₅O₁₃

Purezza: Min. 70%

Colore e forma: Yellow Powder

Peso molecolare: 507.41 g/mol

Ref: 3D-NP140526