CAS 1953-04-4

Idrobromuro di galantamina

Descrizione:

Idrobromuro di galantamina è un inibitore reversibile dell'enzima acetilcolinesterasi, utilizzato principalmente nel trattamento della malattia di Alzheimer da lieve a moderata e di altri disturbi cognitivi. È un composto di ammonio quaternario derivato dalla pianta di galanthus e presenta un meccanismo d'azione duplice, migliorando la funzione colinergica e modulando i recettori nicotinici. La sostanza appare come una polvere cristallina bianca o bianco sporco, è solubile in acqua e ha una formula molecolare che riflette la sua struttura complessa. Idrobromuro di galantamina viene tipicamente somministrato per via orale ed è noto per la sua capacità di migliorare la funzione cognitiva e la memoria nei pazienti. La sua farmacocinetica coinvolge processi di assorbimento, distribuzione, metabolismo ed escrezione che sono influenzati da fattori come età e funzione epatica. Gli effetti collaterali comuni possono includere nausea, vomito e diarrea, che sono generalmente lievi. Come per qualsiasi farmaco, è essenziale utilizzare Idrobromuro di galantamina sotto supervisione medica per monitorare l'efficacia e le potenziali reazioni avverse.

Formula: C₁₇H₂₂BrNO₃

InChI: InChI=1/C17H21NO3/c1-18-8-7-17-6-5-12(19)9-14(17)21-16-13(20-2)4-3-11(10-18)15(16)17/h3-6,12,14,19H,7-10H2,1-2H3/p+1/t12-,14-,17-/m0/s1

InChI key: InChIKey=QORVDGQLPPAFRS-XPSHAMGMSA-N

SMILES: O(C)C1=C2C=3[C@]4([C@@](O2)(C[C@@H](O)C=C4)[H])CCN(C)CC3C=C1.Br

Sinonimi:

• (4aS,6R,8aS)-6-hydroxy-3-methoxy-11-methyl-5,6,9,10,11,12-hexahydro-4aH-[1]benzofuro[3a,3,2-ef][2]benzazepin-11-ium
• 5A,6,7,8,8A,12B-Hexahydrogalanthamine Hydrobromide (1:1)
• 6H-Benzofuro[3a,3,2-ef][2]benzazepin-6-ol, 4a,5,9,10,11,12-hexahydro-3-methoxy-11-methyl-, hydrobromide (1:1), (4aS,6R,8aS)-
• 6H-Benzofuro[3a,3,2-ef][2]benzazepin-6-ol, 4a,5,9,10,11,12-hexahydro-3-methoxy-11-methyl-, hydrobromide, (4aS,6R,8aS)-
• Galantamine Hbr
• Galantamine Hydrobromide
• Galanthamine HBr
• Galanthamine Hydrobromide (1:1)
• Galanthamine hydrogen bromide
• Jilkon hydrobromide
• Lycoremine hydrobromide
• Nivalin
• Nivaline
• Nivaline (pharmaceutical)
• Razadyne
• Reminyl
• Tamilin
• Galanthamine, hydrobromide
• GALANTHAMINE HYDROBROMIDUM
• Galanthamine Hydrobromide Injection
• Hydrobromic acid·galanthamine
• 4A,5,9,10,11,12-HEXAHYDRO-3-METHOXY-11-METHYL-6H-BENZOFURO[3A,3,2-EF][2]BENZAZEPIN-6-OL HYDROBROMIDE
• NIVALIN, HBR
• (-)-Galanthaminium bromide
• GALANTHAMIDE HYDROBROMIDE
• galanthamine hydrobromide from lycoris sp.

Galantamine Hydrobromide

CAS: 1953-04-4, 357-70-0

Formula: C₁₇H₂₁NO₃·HBr

Purezza: >98.0%(T)(HPLC)

Colore e forma: White to Light yellow powder to crystal

Peso molecolare: 368.27

Ref: 3B-G0293

Galanthamine hydrobromide

CAS: 1953-04-4

Centrally active and long-acting acetylcholinesterase inhibitor

Formula: C₁₇H₂₁NO₃•HBr

Peso molecolare: 368.27

Ref: 02-J62482

Galantamine hydrobromide impurity standard

CAS: 1668-85-5, 1953-04-4, 199014-26-1, 60755-80-8

Galantamine hydrobromide impurity standard

Colore e forma: White Powder

Ref: 47-1214

Galantamine hydrobromide

CAS: 1953-04-4

Galantamine hydrobromide

Formula: C₁₇H₂₁NO₃

Purezza: 77.4%

Colore e forma: White

Peso molecolare: 287.15214

Ref: 47-1111

GALANTAMINE HYDROBROMIDE CRS

CAS: 1953-04-4

GALANTAMINE HYDROBROMIDE CRS

Formula: C₁₇H₂₂BrNO₃

Peso molecolare: 368.2655

Ref: 41-Y0001279

GALANTAMINE NATURAL FOR SYSTEM SUITABILITY CRS

CAS: 1953-04-4

GALANTAMINE NATURAL FOR SYSTEM SUITABILITY CRS

Formula: C₁₇H₂₂BrNO₃

Colore e forma: Crystalline Powder. White. Amorphous.

Peso molecolare: 368.2655

Ref: 41-Y0001190

GALANTAMINE SYNTHETIC FOR SYSTEM SUITABILITY CRS

CAS: 1953-04-4

GALANTAMINE SYNTHETIC FOR SYSTEM SUITABILITY CRS

Formula: C₁₇H₂₂BrNO₃

Peso molecolare: 368.2655

Ref: 41-Y0001191

Galantamine Hydrobromide

CAS: 1953-04-4, 69353-21-5

Other alkaloids,natural or reproduced by synthesis, and their salts, ethers,esters&other derivatives, nesoi

Formula: C₁₇H₂₁NO₃·BrH

Colore e forma: White Powder

Peso molecolare: 367.07831

Ref: 45-1287755

(4aS,6R,8aS)-4a,5,9,10,11,12-Hexahydro-3-methoxy-11-methyl-6H-benzofuro[3a,3,2-ef][2]benzazepin-6-ol hydrobromide

CAS: 1953-04-4

Formula: C₁₇H₂₂BrNO₃

Purezza: 98%

Colore e forma: Solid

Peso molecolare: 368.2655

Ref: IN-DA0034YM

Galanthamine hydrobromide

CAS: 1953-04-4

Galanthamine hydrobromide (Galantamine hydrobromide), a long-acting and centrally active AChE inhibitor (IC50:410 nM), is an allosteric potentiator at neuronal

Formula: C₁₇H₂₁NO₃·HBr

Purezza: 98% - 99.49%

Colore e forma: White To Off-White Powder

Peso molecolare: 368.27

Ref: TM-T0086

Galantamine HBr

CAS: 1953-04-4

Formula: C₁₇H₂₁NO₃·HBr

Colore e forma: White To Off-White Solid

Peso molecolare: 287.36 80.91

Ref: 4Z-G-016

Galantamine Hydrobromide

CAS: 1953-04-4

Galantamine Hydrobromide

Purezza: 98%

Peso molecolare: 368.27g/mol

Ref: 54-OR1027829

Galanthamine hydrobromide

CAS: 1953-04-4

Formula: C₁₇H₂₁NO₃HBr

Purezza: ≥ 98.0%

Colore e forma: White powder

Peso molecolare: 368.27

Ref: 7W-GP2704

Galanthamine hydrobromide

CAS: 1953-04-4

Galanthamine hydrobromide

Purezza: ≥98%

Peso molecolare: 368.27g/mol

Ref: 54-BUP11938

Galantamine hydrobromide

Prodotto controllato

CAS: 1953-04-4

Formula: C₁₇H₂₁NO₃·BrH

Colore e forma: White To Off-White

Peso molecolare: 368.27

Ref: 04-C13997200

Galanthamine hydrobromide

CAS: 1953-04-4

Formula: C₁₇H₂₂BrNO₃

Purezza: 95%~99%

Peso molecolare: 368.271

Ref: BP-BP0607

Galantamine Hydrobromide

Prodotto controllato

CAS: 1953-04-4

Formula: C₁₇H₂₁NO₃·BrH

Colore e forma: Neat

Peso molecolare: 368.27

Ref: 86-MM1256.00

Galanthamine hydrobromide

CAS: 1953-04-4

Natural alkaloid

Formula: C₁₇H₂₁NO₃HBr

Purezza: ≥ 95.0 % (HPLC)

Colore e forma: Powder

Peso molecolare: 368.27

Ref: 5G-89666

Galanthamine Hydrobromide

Prodotto controllato

CAS: 1953-04-4

Applications A selective acetylcholinesterase inhibitor. A therapeutic agent for the treatment and prevention of Alzheimer's disease and other diseases resulting from reduced neuronal metabolism.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Friess, S.L., et al.: Toxicol. Appl. Pharmacol., 3, 347 (1961), Bickel, U., et al.: Clin. Pharmacol. Ther., 50, 420 (1991), Harvey, A.L., et al.: Pharmacol. Ther., 68, 113 (1995),

Formula: C₁₇H₂₁NO₃·BrH

Colore e forma: White To Off-White

Peso molecolare: 368.27

Ref: TR-G188500

Galanthamine hydrobromide

Prodotto controllato

CAS: 1953-04-4

A reversible and competitive inhibitor of acetylcholinesterase (AChE) that is approved for the treatment of Alzheimer’s disease. It is also an allosteric modulator of nicotinic acetylcholine receptors (nAChR). Activation of nAChR along with upregulation of anti-apoptotic protein Bcl-2 prevents apoptosis and therefore provides neuroprotection.

Formula: C₁₇H₂₁NO₃·HBr

Purezza: Min. 95%

Colore e forma: Powder

Peso molecolare: 368.27 g/mol

Ref: 3D-FH15701

Galanthamine-O-methyl-d3 Hydrobromide

Prodotto controllato

CAS: 1953-04-4

Formula: C₁₇D₃H₁₈NO₃·HBr

Colore e forma: Neat

Peso molecolare: 371.284

Ref: TR-G188504

9-Bromo-7-methoxy-1,2,3,4-tetrahydrobenzofuro[4,3-cd]azepine Hydrobromide

Prodotto controllato

CAS: 1953-04-4

Formula: C₁₂H₁₂BrNO₂·HBr

Colore e forma: Neat

Peso molecolare: 363.05

Ref: TR-B188550

Galantamine Hydrobromide extrapure, 98%

CAS: 1953-04-4

Formula: C₁₇H₂₁NO₃·HBr

Purezza: min. 98%

Colore e forma: White to off - white, Hygroscopic crystalline powder

Peso molecolare: 368.27

Ref: SR-83055