CAS 195514-80-8

2,2′-[[2-[(Dimetilamino)metil]-1,3-propanediyl]bis[imino(2-oxo-2,1-etandioil)ossi-3,1-fenilene[(1R)-3-(3,4-dimetossifenil)propilidene]]] bis[1-[(2S)-1-osso-2-(3,4,5-trimetossifenil)butil]-2-piperidinocarbossilato]

Descrizione:

La sostanza chimica con il nome "2,2′-[[2-[(Dimetilamino)metil]-1,3-propanediyl]bis[imino(2-oxo-2,1-etandioil)ossi-3,1-fenilene[(1R)-3-(3,4-dimetossifenil)propilidene]]] bis[1-[(2S)-1-osso-2-(3,4,5-trimetossifenil)butil]-2-piperidinocarbossilato]" e numero CAS "195514-80-8" è un composto organico complesso caratterizzato dalla sua intricatissima struttura molecolare, che include più gruppi funzionali come imino, piperidina e gruppi metossilici. Questo composto è probabile che mostri un'attività biologica significativa a causa delle sue caratteristiche strutturali, che possono facilitare interazioni con bersagli biologici. La sua solubilità, stabilità e reattività possono variare a seconda delle condizioni specifiche, come pH e solvente. La presenza di gruppi dimetilamminici suggerisce un potenziale per la basicità, mentre i gruppi metossilici possono influenzare la sua lipofilia e le proprietà farmacocinetiche complessive. Tali composti sono spesso studiati per le loro potenziali applicazioni in campo farmaceutico, in particolare nello sviluppo di agenti terapeutici. Tuttavia, sarebbero necessari studi dettagliati per chiarire completamente le loro proprietà e potenziali usi.

Formula: C₈₂H₁₀₇N₅O₂₀

InChI: InChI=1S/C82H107N5O20/c1-15-61(57-43-71(98-9)77(102-13)72(44-57)99-10)79(90)86-37-19-17-27-63(86)81(92)106-65(33-29-52-31-35-67(94-5)69(39-52)96-7)55-23-21-25-59(41-55)104-50-75(88)83-47-54(49-85(3)4)48-84-76(89)51-105-60-26-22-24-56(42-60)66(34-30-53-32-36-68(95-6)70(40-53)97-8)107-82(93)64-28-18-20-38-87(64)80(91)62(16-2)58-45-73(100-11)78(103-14)74(46-58)101-12/h21-26,31-32,35-36,39-46,54,61-66H,15-20,27-30,33-34,37-38,47-51H2,1-14H3,(H,83,88)(H,84,89)/t61-,62-,63-,64-,65+,66+/m0/s1

InChI key: InChIKey=NSBGUMKAXUXKGI-BPNHAYRBSA-N

SMILES: [C@H](C(=O)N1[C@H](C(O[C@H](CCC2=CC(OC)=C(OC)C=C2)C3=CC(OCC(NCC(CNC(COC4=CC([C@H](OC(=O)[C@H]5N(C([C@@H](CC)C6=CC(OC)=C(OC)C(OC)=C6)=O)CCCC5)CCC7=CC(OC)=C(OC)C=C7)=CC=C4)=O)CN(C)C)=O)=CC=C3)=O)CCCC1)(CC)C8=CC(OC)=C(OC)C(OC)=C8

Sinonimi:

• 2-Piperidinecarboxylic acid, 1-[(2S)-1-oxo-2-(3,4,5-trimethoxyphenyl)butyl]-, 2,2′-[[2-[(dimethylamino)methyl]-1,3-propanediyl]bis[imino(2-oxo-2,1-ethanediyl)oxy-3,1-phenylene[(1R)-3-(3,4-dimethoxyphenyl)propylidene]]] ester, (2S,2′S)-
• AP 20187
• 2-Piperidinecarboxylic acid, 1-[(2S)-1-oxo-2-(3,4,5-trimethoxyphenyl)butyl]-, [2-[(dimethylamino)methyl]-1,3-propanediyl]bis[imino(2-oxo-2,1-ethanediyl)oxy-3,1-phenylene[(1R)-3-(3,4-dimethoxyphenyl)propylidene]] ester, (2S,2′S)-
• 2-Piperidinecarboxylic acid, 1-[1-oxo-2-(3,4,5-trimethoxyphenyl)butyl]-, [2-[(dimethylamino)methyl]-1,3-propanediyl]bis[imino(2-oxo-2,1-ethanediyl)oxy-3,1-phenylene[3-(3,4-dimethoxyphenyl)propylidene]] ester, [2S-[1(R*),2R*[S*[S*[1(R*),2R*]]]]]-
• 2,2′-[[2-[(Dimethylamino)methyl]-1,3-propanediyl]bis[imino(2-oxo-2,1-ethanediyl)oxy-3,1-phenylene[(1R)-3-(3,4-dimethoxyphenyl)propylidene]]] bis[1-[(2S)-1-oxo-2-(3,4,5-trimethoxyphenyl)butyl]-2-piperidinecarboxylate]
• AP20187
• (1R,1'R)-(((((2-((dimethylamino)methyl)propane-1,3-diyl)bis(azanediyl))bis(2-oxoethane-2,1-diyl))bis(oxy))bis(3,1-phenylene))bis(3-(3,4-dimethoxyphenyl)propane-1,1-diyl) (2S,2'S)-bis(1-((S)-2-(3,4,5-trimethoxyphenyl)butanoyl)piperidine-2-carboxylate)
• B/B Homodimerizer
• AP20187;AP-20187;AP 20187
• (1R)-3-(3,4-dimethoxyphenyl)-1-[3-[2-[[2-[[[2-[3-[(1R)-3-(3,4-dimethoxyphenyl)-1-[(2S)-1-[(2S)-2-(3,4,5-trimethoxyphenyl)butanoyl]piperidine-2-carbonyl]oxypropyl]phenoxy]acetyl]amino]methyl]-3-(dimethylamino)propyl]amino]-2-oxoethoxy]phenyl]propyl] (2S)-1-[(2S)-2-(3,4,5-trimethoxyphenyl)butanoyl]piperidine-2-carboxylate

AP20187

CAS: 195514-80-8

AP20187: Cell-permeable ligand dimerizing FKBP fusion proteins for signaling and gene expression control.

Formula: C₈₂H₁₀₇N₅O₂₀

Purezza: 99.05% - 99.80%

Colore e forma: Solid

Peso molecolare: 1482.75

Ref: TM-T14299

AP20187

CAS: 195514-80-8

Formula: C₈₂H₁₀₇N₅O₂₀

Purezza: 99%

Peso molecolare: 1482.7485

Ref: IN-DA00ABIM

AP20187

CAS: 195514-80-8

AP20187

Purezza: ≥98%

Peso molecolare: 1482.75g/mol

Ref: 54-BUP04709

AP20187

CAS: 195514-80-8

AP20187 is a synthetic small molecule that functions as a chemical dimerizer, originating from the FKBP-binding domain technology. Its mode of action relies on promoting the dimerization of proteins fused with FKBP domains. This dimerization process triggers downstream signaling pathways or protein interactions within cells, providing a tool for controlled manipulation of cellular processes.

Formula: C₈₂H₁₀₇N₅O₂₀

Purezza: Min. 95%

Peso molecolare: 1,482.75 g/mol

Ref: 3D-VHA51480