CAS 19660-77-6

Clorina e6

Descrizione:

Clorina e6, noto anche come Clorina e6 o Clorina e6 (C6H6N4O4), è un derivato della clorofilla che presenta proprietà fotofisiche e fotochimiche uniche, rendendolo prezioso in varie applicazioni, in particolare nella terapia fotodinamica (PDT) e come fotosensibilizzatore. Questo composto è caratterizzato dalla sua capacità di assorbire luce nello spettro visibile, in particolare nella regione rossa, il che ne aumenta l'efficacia nelle applicazioni terapeutiche. Clorina e6 è noto per la sua alta efficienza nella generazione di ossigeno singoletto dopo attivazione luminosa, fondamentale per indurre effetti citotossici nelle cellule tumorali bersaglio. Inoltre, possiede una solubilità relativamente alta nei solventi organici, il che facilita il suo utilizzo in formulazioni per scopi medici e di ricerca. Le sue caratteristiche strutturali includono un nucleo centrale simile alla porfirina con vari sostituenti che influenzano la sua reattività e interazione con i sistemi biologici. In generale, Clorina e6 è un composto promettente nei campi della medicina e della biotecnologia, in particolare per il suo potenziale nel trattamento del cancro e nelle applicazioni di imaging.

Formula: C₃₄H₃₆N₄O₆

InChI: InChI=1S/C34H36N4O6/c1-7-19-15(3)23-12-25-17(5)21(9-10-29(39)40)32(37-25)22(11-30(41)42)33-31(34(43)44)18(6)26(38-33)14-28-20(8-2)16(4)24(36-28)13-27(19)35-23/h7,12-14,17,21,35,38H,1,8-11H2,2-6H3,(H,39,40)(H,41,42)(H,43,44)/b23-12?,24-13-,25-12-,26-14-,27-13?,28-14?,32-22?,33-22-/t17-,21-/m0/s1

InChI key: InChIKey=VAJLRIOJDADNAT-QXILTCMVSA-N

SMILES: C(C(O)=O)C1=C2[C@@H](CCC(O)=O)[C@H](C)C(=N2)C=C3NC(C(C=C)=C3C)=CC4=NC(=CC=5NC1=C(C(O)=O)C5C)C(CC)=C4C

Sinonimi:

• (17S,18S)-18-(2-carboxyethyl)-20-(carboxymethyl)-12-ethenyl-7-ethyl-3,8,13,17-tetramethyl-17,18-dihydroporphyrin-2-carboxylic acid
• (7S,8S)-3-Carboxy-5-(carboxymethyl)-13-ethenyl-18-ethyl-7,8-dihydro-2,8,12,17-tetramethyl-21H,23H-porphine-7-propanoic acid
• 18-(2-Carboxyethyl)-20-(Carboxymethyl)-12-Ethenyl-7-Ethyl-3,8,13,17-Tetramethyl-17,18-Dihydroporphyrin-2-Carboxylic Acid
• 2-Porphinepropionic acid, 18-carboxy-20-(carboxymethyl)-13-ethyl-2β,3-dihydro-3β,7,12,17-tetramethyl-8-vinyl-
• 21H,23H-Porphine-2-propanoic acid, 18-carboxy-20-(carboxymethyl)-8-ethenyl-13-ethyl-2,3-dihydro-3,7,12,17-tetramethyl-,(2S-trans)-
• 21H,23H-Porphine-7-propanoic acid, 3-carboxy-5-(carboxymethyl)-13-ethenyl-18-ethyl-7,8-dihydro-2,8,12,17-tetramethyl-, (7S,8S)-
• Chlorin a₆
• Chlorin e6
• Chlorin e₆
• Chlorine a₆
• Chlorine e₆
• Chlorophyllin
• Photochlorine
• Photolon
• Phytochlorin
• Phytochlorin e₆
• Phytochlorine e₆
• (2S-trans)-18-Carboxy-20-(carboxymethyl)-13-ethyl-2,3-dihydro-3,7,12,17-tetramethyl-8-vinyl-21H,23H-porphine-2-propionic acid

21H,23H-Porphine-7-propanoic acid,3-carboxy-5-(carboxymethyl)-13-ethenyl-18-ethyl-7,8-dihydro-2,8,12,17-tetramethyl-, (7S,8S)-

CAS: 19660-77-6

Formula: C₃₄H₃₈N₄O₆

Purezza: 90%

Colore e forma: Solid

Peso molecolare: 598.6887

Ref: IN-DA00I3KS

Chlorin e6

CAS: 19660-77-6

Chlorin e6

Formula: C₃₄H₃₆N₄O₆

Purezza: 90%

Colore e forma: light brown to black solid

Peso molecolare: 596.67g/mol

Ref: 54-OR61545

Chlorin E6

CAS: 19660-77-6

Chlorin E6

Purezza: ≥90%

Peso molecolare: 596.67g/mol

Ref: 54-BUP06858

Chlorin e6

CAS: 19660-77-6

Formula: C₃₄H₃₆N₄O₆

Purezza: 93%-98%

Colore e forma: Ce

Peso molecolare: 596.673

Ref: FT-Ce6

Chlorin e6

CAS: 19660-77-6

Formula: C₃₄H₃₆N₄O₆

Purezza: 93%-98%

Colore e forma: Ce

Peso molecolare: 596.673

Ref: FT-CE6

Chlorin E6

Prodotto controllato

CAS: 19660-77-6

Applications Chlorin E6 is a photosensitizer.The conjugates of gold nanorods and chlorin e6 enhance the fluorescence detection and photodynamic therapy (PDT) of cancers.
References Schmidt-Erfurth, U., et al.: Brit. J. Cancer, 75, 54 (1997); Huang, X., et al.: Phys. Chem. Chem. Phys., 15, 15727 (2013)

Formula: C₃₄H₃₆N₄O₆

Colore e forma: Neat

Peso molecolare: 596.67

Ref: TR-C380285

Chlorin E6

CAS: 19660-77-6

CE6 is a photosensitizer effective against tumors with light exposure, shown successful in mouse models and human trials for bronchial and lung cancer.

Formula: C₃₄H₃₆N₄O₆

Purezza: 90.964% - 95.05%

Colore e forma: Solid

Peso molecolare: 596.67

Ref: TM-T36466

Chlorin e6

CAS: 19660-77-6

Chlorin e6 is a photosensitizer, which is derived from chlorophyll, specifically the breakdown products of chlorophyll a extracted from plants and algae. It has a significant absorption in the red and near-infrared region of the electromagnetic spectrum, facilitating its use in photodynamic therapy (PDT). Upon activation by light, chlorin e6 produces reactive oxygen species, including singlet oxygen, which can induce cell death. This photochemical mechanism allows for the targeted destruction of cancer cells when used in oncological settings.

Formula: C₃₄H₃₆N₄O₆

Purezza: 90%Min

Colore e forma: Dark Blue-Green Or Dark Purple Solid

Peso molecolare: 596.67 g/mol

Ref: 3D-FC145291

Chlorin e6

CAS: 19660-77-6

Purezza: 90%

Peso molecolare: 596.684021

Ref: 10-F868774