CAS 198561-07-8

FMOC-L-PROPARGILGLICINA

Descrizione:

FMOC-L-PROPARGILGLICINA è un composto chimico che funge da blocco di costruzione nella sintesi dei peptidi ed è particolarmente notevole per il suo ruolo nello sviluppo di reazioni bioortogonali. Presenta un gruppo protettivo fluorenilmetossicarbonilico (FMOC), comunemente usato per proteggere i gruppi amminici durante la sintesi dei peptidi, consentendo reazioni selettive. Il gruppo propargile nella sua struttura introduce una funzionalità alchino, permettendogli di partecipare alla chimica click, in particolare con azidi, facilitando la formazione di legami triazolici stabili. Questo composto è tipicamente utilizzato nella ricerca e nelle applicazioni farmaceutiche, specialmente nella sintesi di peptidi che richiedono modifiche o funzionalizzazioni specifiche. La sua stabilità in condizioni di laboratorio standard lo rende un reagente prezioso nella sintesi organica. Inoltre, FMOC-L-PROPARGILGLICINA è caratterizzato dalla sua solubilità in solventi organici, il che è vantaggioso per vari procedimenti sintetici. Come per tutte le sostanze chimiche, è necessario osservare le adeguate precauzioni di manipolazione e sicurezza a causa dei potenziali pericoli associati al suo uso.

Formula: C₂₀H₁₇NO₄

InChI: InChI=1/C20H17NO4/c1-2-7-18(19(22)23)21-20(24)25-12-17-15-10-5-3-8-13(15)14-9-4-6-11-16(14)17/h1,3-6,8-11,17-18H,7,12H2,(H,21,24)(H,22,23)/t18-/m1/s1

InChI key: InChIKey=DJGMNCKHNMRKFM-SFHVURJKSA-N

SMILES: C(OC(N[C@@H](CC#C)C(O)=O)=O)C1C=2C(C=3C1=CC=CC3)=CC=CC2

Sinonimi:

• (2R)-2-{[(9H-fluoren-9-ylmethoxy)carbonyl]amino}pent-4-ynoic acid
• (2S)-2-(9H-Fluoren-9-ylmethoxycarbonylamino)pent-4-ynoic acid
• (2S)-2-[[(9H-Fluoren-9-ylmethoxy)carbonyl]amino]-4-pentynoic acid
• (2S)-2-{[(9H-fluoren-9-ylmethoxy)carbonyl]amino}pent-4-ynoic acid
• (S)-2-(Fmoc-Amino)-4-Pentynoic Acid
• 4-Pentynoic acid, 2-[[(9H-fluoren-9-ylmethoxy)carbonyl]amino]-, (2S)-
• 4-Pentynoic acid, 2-[[(9H-fluoren-9-ylmethoxy)carbonyl]amino]-, (S)-
• Fmoc-(S)-2-Propargylglycine
• Fmoc-<span class="text-smallcaps">L</span>-propargylglycine
• Fmoc-Pra-Oh
• N-Alpha-(9-Fluorenylmethoxycarbonyl)-(S)-2-Amino-4-Pentynoic Acid
• N-Alpha-(9-Fluorenylmethoxycarbonyl)-Propargylglycine
• N-Alpha-(9-Fluorenylmethyloxycarbonyl)-L-Propargylglycine
• Rarechem Bk Pt 0257
• Fmoc-L-propargylglycine
• N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-L-propargylglycine&gt
• FMOC-L-PROPARGYL-GLY-OH
• N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-L-propargylglycine
• (S)-N-FMoc-2-(2'-propynyl)glycine
• (S)-2-(Fmoc-amino)-4-pentynoic acid, Fmoc-L-2-propargylglycine
• Fmoc-Pra-OH Fmoc-Propargylglycine
• N-Fmoc-L-propargylglycine,95%
• (S)-N-(9-FLUORENYLMETHOXYCARBONYL)-2-AMINO-4-PENTYNOIC ACID
• FMOC-GLY(PROPARGYL)-OH
• Fmoc-L-propargylglycine Novabiochem
• Fmoc-L-propargylglycine≥ 99% (HPLC, Chiral purity)
• N-alpha-(9-Fluorenylmethyloxycarbonyl)-L-propargylglycine, (S)-2-(Fmoc-amino)-4-pentynoic acid
• (S)-N-FMOC-PROPARGYLGLYCINE
• 4-Pentynoicacid, 2-[[(9H-fluoren-9-ylmethoxy)carbonyl]amino]-, (2S)-
• N-FMoc-L-propargylglycine, 95%
• N-Fluorenemethoxycarbonyl-L-Propargyl Glycine
• L-2-Propargylglycine, N-FMOC protected
• (S)-2-(((9H-Fluoren-9-yl)methoxy)carbonylamino)pent-4-ynoic acid
• FMOC-L-2-PROPARGYLGLYCINE
• FMoc-Propargyl-Gly-OH, (S)-2-(FMoc-aMino)-4-pentynoic acid
• FMOC-L-PRA-OH
• (S)-N-FMOC-Propargylglycine, 98% ee, 95%
• Fmoc-propargyl-Gly-OH
• (S)-2-(Fmoc-amino)-4-pentynoic
• (9H-Fluoren-9-yl)MethOxy]Carbonyl Pra-OH
• Fmoc-Pra-OH（Fmoc-Propargly-Gly-OH）
• (S)-N-fmoc-Propargylglycine(e.e.)

N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-L-propargylglycine

CAS: 198561-07-8

Formula: C₂₀H₁₇NO₄

Purezza: >98.0%(T)(HPLC)

Colore e forma: White to Almost white powder to crystal

Peso molecolare: 335.36

Ref: 3B-F0926

N-Fmoc-L-propargylglycine, 95%

CAS: 198561-07-8

Fmoc-propargyl-Gly-OH is an Fmoc protected glycine derivative useful for solid phase peptide synthesis techniques. This compound could be useful as an unusual amino acid analog to aid in the deconvolution of protein structure and function. N-Fmoc-L-propargylglycine is a non-natural amino acids used

Formula: C₂₀H₁₇NO₄

Purezza: 95%

Colore e forma: White, Powder

Peso molecolare: 335.36

Ref: 02-H52171

Fmoc-L-propargylglycine

CAS: 198561-07-8

Formula: C₂₀H₁₇NO₄

Purezza: 97%

Colore e forma: Solid, Crystalline Powder or Powder

Peso molecolare: 335.359

Ref: 10-F492822

Fmoc-Pra-OH

CAS: 198561-07-8

Building block for the synthesis of precursor peptides for tritiation, and for “click chemistry”. Pra-containing peptides have been modified by 1,3-dipolar cycloaddition, e.g. with alkyl azides. Peptides containing a Pra residue and an α-azido acid have been cyclized in the presence of CuBr/Na-ascorbate via triazole formation. Educt for the synthesis of Phe-derivatives by rhodium-catalyzed [2+2+2] cycloaddition.

Formula: C₂₀H₁₇NO₄

Purezza: 99.9%

Colore e forma: White

Peso molecolare: 335.36

Ref: 01-4053914

4-Pentynoic acid, 2-[[(9H-fluoren-9-ylmethoxy)carbonyl]amino]-, (2S)-

CAS: 198561-07-8

Formula: C₂₀H₁₇NO₄

Purezza: 97%

Colore e forma: Solid

Peso molecolare: 335.3533

Ref: IN-DA002BML

Fmoc-propargyl-Gly-OH

CAS: 198561-07-8

Formula: C₂₀H₁₇NO₄

Purezza: ≥ 98.0%

Colore e forma: White to almost white powder or crystals

Peso molecolare: 335.36

Ref: 7W-GM4391

L-2-Propargylglycine, N-FMOC protected

CAS: 198561-07-8

L-2-Propargylglycine, N-FMOC protected

Formula: C₂₀H₁₇NO₄

Purezza: 98%

Colore e forma: off-white solid

Peso molecolare: 335.35328g/mol

Ref: 54-OR14676

Fmoc-Pra-OH

CAS: 198561-07-8

Fmoc-Pra-OH is a bioconjugate used in Click Chemistry. Click Chemistry is a chemical reaction that joins two components together by forming an amide bond between the carboxyl group of one component and the amino group on the other component. Fmoc-Pra-OH was synthesized by reacting the epidermal growth factor (EGF) with a cyclic peptide containing an acid moiety, which was conjugated to the azide group of an azidopropargyl linker. This bioconjugate has been shown to have proliferative activity in vitro and structural studies have been performed to understand its reactivity.

Formula: C₂₀H₁₇NO₄

Purezza: Min. 98.0 Area-%

Peso molecolare: 335.36 g/mol

Ref: 3D-PRA-5010-PI

Fmoc-L-propargylglycine

CAS: 198561-07-8

Fmoc-L-propargylglycine is a cyclic peptide that is synthesized by chemical ligation. It has antiviral, anti-tumor, and anti-inflammatory activities. Fmoc-L-propargylglycine inhibits the growth of cancer cells in vitro. The mechanism of action is not fully understood, but it may involve the inhibition of cellular proliferation and the induction of apoptosis. This compound also inhibits epidermal growth factor (EGF) induced cell proliferation in caco-2 cells.

Formula: C₂₀H₁₇NO₄

Purezza: Min. 98 Area-%

Colore e forma: White Powder

Peso molecolare: 335.35 g/mol

Ref: 3D-FF40126

Fmoc-l-propargylglycine

Prodotto controllato

CAS: 198561-07-8

Applications Fmoc-l-propargylglycine has been used to study the bioorthogonal chemical tagging of protein cholesterylation in living cells.
References William P. H., et al., ChemComm., 47, 4081-4083 (2011)

Formula: C₂₀H₁₇NO₄

Colore e forma: Neat

Peso molecolare: 335.35

Ref: TR-F861030