CAS 2026-48-4

1-Butanolo, 2-ammino-3-metil-, (2S)-

Descrizione:

1-Butanolo, 2-ammino-3-metil-, (2S)-, noto anche come (S)-2-amino-3-metil-1-butanolo, è un composto organico caratterizzato dalla sua struttura di aminoalcol. Presenta uno scheletro di butanolo con un gruppo amminico (-NH2) e un gruppo metile (-CH3) attaccati al secondo e terzo atomo di carbonio, rispettivamente. Questo composto è una molecola chirale, con la designazione (2S) che indica la sua stereochimica specifica. È tipicamente un liquido incolore a giallo pallido con un odore caratteristico ed è solubile in acqua grazie alla presenza del gruppo idrossile (-OH). La presenza di entrambi i gruppi funzionali, amminico e idrossile, consente di partecipare a legami idrogeno, influenzando le sue proprietà fisiche e reattività. 1-Butanolo, 2-ammino-3-metil-, (2S)- è spesso utilizzato in varie sintesi chimiche e può fungere da intermedio nella produzione di prodotti farmaceutici o agrochimici. La sua attività biologica e le potenziali applicazioni in chimica medicinale sono aree di ricerca in corso.

Formula: C₅H₁₃NO

InChI: InChI=1S/C5H13NO/c1-4(2)5(6)3-7/h4-5,7H,3,6H2,1-2H3/t5-/m1/s1

InChI key: InChIKey=NWYYWIJOWOLJNR-RXMQYKEDSA-N

SMILES: [C@H](C(C)C)(CO)N

Sinonimi:

• (+)-(S)-Valinol
• (+)-2-Amino-3-methyl-1-butanol
• (+)-Valinol
• (2S)-1-Hydroxy-3-methylbutan-2-amine
• (2S)-2-Amino-3-methyl-1-butanol
• (2S)-Valinol
• (S)-(+)-2-Amino-3-methyl-1-butanol
• (S)-2-Amino-3-methylbutanol
• 1-Butanol, 2-amino-3-methyl-, (S)-
• 1-Butanol, 2-amino-3-methyl-, <span class="text-smallcaps">L</span>-
• 1-Butanol, 2-amino-3-methyl-, L-
• <span class="text-smallcaps">L</span>-Valinol
• Butanol, 2-Amino-3-Methyl, (S)-(+)-
• L-2-amino-3-methylbutan-1-ol
• L-2-amino-3-methylbutane-1-ol
• L-2-amino-3-metilbutan-1-ol
• L-Valinol
• Nsc 322922
• [(S)-1-(Hydroxymethyl)-2-methylpropyl]amine
• Valinol,97%
• (2R)-2-amino-3-methylbutan-1-ol
• 1-Butanol, 2-amino-3-methyl-, (2S)-
• H-Val-ol
• (S)-2-Amino-3-methyl-butanol

L-Valinol

CAS: 2026-48-4

Formula: C₅H₁₃NO

Purezza: >97.0%(GC)(T)

Colore e forma: White or Colorless to Light orange to Yellow powder to lump to clear liquid

Peso molecolare: 103.17

Ref: 3B-V0058

L-(+)-Valinol, 97%

CAS: 2026-48-4

L-(+)-Valinol reacts with aldehydes and nitriles to form imines and oxazolines, respectively, for asymmetric synthesis. It is also used for preparation of 4-isopropyloxazolidinones, employed in stereocontrolled aldol and alkylation reactions, synthesis of chiral 2-thiazolidinethiones for aldol react

Formula: C₅H₁₃NO

Purezza: 97%

Colore e forma: Colourless/white to yellow, liquid/low melting solid

Peso molecolare: 103.17

Ref: 02-L11300

1-Butanol, 2-amino-3-methyl-, (2S)-

CAS: 2026-48-4

Formula: C₅H₁₃NO

Purezza: 96%

Colore e forma: Liquid

Peso molecolare: 103.1628

Ref: IN-DA0028CI

(S)-(+)-2-Amino-3-methyl-1-butanol

CAS: 2026-48-4

(S)-(+)-2-Amino-3-methyl-1-butanol

Formula: C₅H₁₃NO

Purezza: 97%

Colore e forma: colourless to light yellow crystalline solid

Peso molecolare: 103.16g/mol

Ref: 54-OR5874

L-Valinol

CAS: 2026-48-4

Colore e forma: Neat

Ref: 86-MM3372.23

L-Valinol

CAS: 2026-48-4

Formula: C₅H₁₃NO

Purezza: ≥ 97.0%

Colore e forma: Colourless to white or pale yellow solid, crystals or liquid

Peso molecolare: 103.17

Ref: 7W-GM8064

L-Valinol

CAS: 2026-48-4

L-Valinol is a model system that is used to study the reaction of aziridines with oxygen nucleophiles. It has been shown that this reaction proceeds through the formation of an intermediate, hydrogen tartrate, followed by a second step with nitrogen atoms as the nucleophile and alcohol residue as the substrate. The use of L-valinol in asymmetric synthesis was also demonstrated. In this process, amides were obtained with high enantioselectivity by reacting L-valinol with amines in acidic conditions. This synthetic pathway was found to be synergic with other reactions, such as nitroolefination and benzoylation.

Formula: C₅H₁₃NO

Purezza: Min. 95%

Colore e forma: Solidified Mass

Peso molecolare: 103.16 g/mol

Ref: 3D-FV10652

L-Valinol

CAS: 2026-48-4

M03447 - L-Valinol

Formula: C₅H₁₃NO

Purezza: 95%

Colore e forma: Liquid

Peso molecolare: 103.165

Ref: 10-M03447

L-Valinol

Prodotto controllato

CAS: 2026-48-4

Applications L-Valinol is used as a reagent in the synthesis of simple 1,3-thiazolidine-2-thione derivatives which can exhibit fungicidal activity. L-Valinol is also used as a reagent in the synthesis of small-molecule inhibitors of MDM2-p53 protein-protein interaction (MDM2 inhibitors) in clinical trials for the treatment of cancer.
References Chen, N., et al.: Phosphorus Sulfur, 190, 112 (2015); Zhao, Y., et al.: J. Med. Chem., 58, 1038 (2015)

Formula: C₅H₁₃NO

Colore e forma: White

Peso molecolare: 103.163

Ref: TR-V094340