CAS 20290-09-9

soluzione di morfina-3-β-D-glucuronide*metanolo

Descrizione:

La morfina-3-β-D-glucuronide (M3G) è un metabolita della morfina, formato attraverso la coniugazione della morfina con acido glucuronico. È principalmente conosciuta per il suo ruolo nella farmacocinetica della morfina, poiché è uno dei principali metaboliti escreti nelle urine. M3G è meno potente della morfina in termini di effetti analgesici, ma può contribuire al profilo farmacologico complessivo della morfina. La soluzione di metanolo indica che M3G è disciolto in metanolo, un solvente polare comunemente usato in contesti di laboratorio. Questa soluzione può essere utilizzata per vari scopi analitici, inclusa la cromatografia o studi spettroscopici. M3G è caratterizzata dalla sua solubilità in solventi polari e la sua struttura chimica include un gruppo acido glucuronico, che ne aumenta la solubilità in acqua rispetto alla morfina. Il composto è tipicamente studiato per le sue implicazioni nella gestione del dolore e nel metabolismo degli oppioidi, così come per i suoi potenziali effetti sul sistema nervoso centrale. Le precauzioni di sicurezza e di manipolazione sono essenziali a causa dell'attività farmacologica dei derivati della morfina.

Formula: C₂₃H₂₇NO₉

InChI: InChI=1/C23H27NO9/c1-24-7-6-23-10-3-4-12(25)20(23)32-18-13(5-2-9(14(18)23)8-11(10)24)31-22-17(28)15(26)16(27)19(33-22)21(29)30/h2-5,10-12,15-17,19-20,22,25-28H,6-8H2,1H3,(H,29,30)/t10-,11+,12-,15-,16-,17+,19-,20-,22+,23-/m0/s1

InChI key: InChIKey=WAEXKFONHRHFBZ-ZXDZBKESSA-N

SMILES: O[C@@H]1[C@]2([C@]34C=5C(O2)=C(O[C@@H]6O[C@H](C(O)=O)[C@@H](O)[C@H](O)[C@H]6O)C=CC5C[C@]([C@@]3(C=C1)[H])(N(C)CC4)[H])[H]

Sinonimi:

• (-)-Morphine 3-glucuronide
• (5alpha,6alpha)-6-hydroxy-17-methyl-7,8-didehydro-4,5-epoxymorphinan-3-yl beta-D-glucopyranosiduronic acid
• (5α,6α)-7,8-Didehydro-4,5-epoxy-6-hydroxy-17-methylmorphinan-3-yl β-<span class="text-smallcaps">D</span>-glucopyranosiduronic acid
• 3-Glucuronosidomorphine
• Glucopyranosiduronic acid, 7,8-didehydro-4,5α-epoxy-6α-hydroxy-17-methylmorphinan-3-yl, β-<span class="text-smallcaps">D</span>-
• Glucopyranosiduronic acid, morphine-3, β-<span class="text-smallcaps">D</span>-
• Morphinan, β-<span class="text-smallcaps">D</span>-glucopyranosiduronic acid deriv.
• Morphinan-6α-ol, 7,8-didehydro-4,5α-epoxy-3-(β-<span class="text-smallcaps">D</span>-glucopyranuronosyloxy)-17-methyl-
• Morphine 3-O-glucuronide
• Morphine 3-O-monoglucuronide
• Morphine 3-O-β-<span class="text-smallcaps">D</span>-glucuronide
• Morphine 3-glucopyranuronide
• Morphine 3-β-<span class="text-smallcaps">D</span>-glucuronide
• Morphine 3-β-glucuronide
• morphine-3-B-D-glucuronide--dea*schedule ii item
• β-<span class="text-smallcaps">D</span>-Glucopyranosiduronic acid, (5α,6α)-7,8-didehydro-4,5-epoxy-6-hydroxy-17-methylmorphinan-3-yl
• Glucopyranosiduronic acid, 7,8-didehydro-4,5α-epoxy-6α-hydroxy-17-methylmorphinan-3-yl, β-D-
• Morphinan-6α-ol, 7,8-didehydro-4,5α-epoxy-3-(β-D-glucopyranuronosyloxy)-17-methyl-
• Glucopyranosiduronic acid, morphine-3, β-D-
• Morphinan, β-D-glucopyranosiduronic acid deriv.
• β-D-Glucopyranosiduronic acid, (5α,6α)-7,8-didehydro-4,5-epoxy-6-hydroxy-17-methylmorphinan-3-yl
• MORPHINE-3-BETA-D-GLUCURONIDE HYDRATE
• morphine-3-B-D-glucuronide*methanol solution
• Morphine 3-b-D-Glucuronide
• MORPHINE-3-B-D-GLUCURONIDE MAJOR METABOL ITE OF M
• M-3-G HYDRATE
• Morphine 3-β-D-glucuronide solution
• Morphine-3-Glucuronide-d3
• beta-D-Glucopyranosiduronic acid, (5alpha,6alpha)-7,8-didehydro-4,5-epoxy-6-hydroxy-17-methylmorphinan-3-yl
• m3g
• (6α-Hydroxy-17-methyl-7,8-didehydro-4,5α-epoxymorphinan-3-yl)β-D-glucopyranosiduronic acid
• (5a,6a)-7,8-Didehydro-4,5-epoxy-6-hydroxy-17-methylmorphinan-3-yl b-d-Glucopyranosiduronic Acid
• (5a,6a)-7,8-Didehydro-4,5-epoxy-6-hydroxy-17-methylmorphinan-3-yl -d-Glucopyranosiduronic Acid
• MORPHINE-3BETA-D-GLUCURONIDE,100/MLINMETHANOL
• MORPHINE-3BETA-D-GLUCURONIDE,1.0MG/MLINMETHANOL
• Morphine-O-glucuronide
• MORPHINE-3-BETA-D-GLUCURONIDE
• Morphine-β-D-Glucuronide (0.1 mg/mL in Methanol/Water 1:1)
• morphine 3-β-d-glucuronide
• Methanol w/0.05% NaOH（test Morphine-3-β-D-glucuronide ，1.0 mg/Ml）

Morphine-3-β-D-glucuronide

Prodotto controllato

CAS: 20290-09-9

Colore e forma: Neat

Ref: LP-M-10-HY-10

Morphine-3-β-D-glucuronide

Prodotto controllato

CAS: 20290-09-9

Colore e forma: Neat

Ref: 61-FOR0037.15

Morphine-3-β-D-glucuronide, 1mg/ml in Methanol/Water : 1/1

Prodotto controllato

CAS: 20290-09-9

Colore e forma: Single Solution

Ref: LP-M-10-HY-1LMH

Morphine 3-β-D-Glucuronide (1 mg/mL in Methanol w/0.05% NaOH)

Prodotto controllato

CAS: 20290-09-9

Formula: C₂₃H₂₇NO₉

Colore e forma: Single Solution

Peso molecolare: 461.46

Ref: TR-KIT0510

Morphine 3-β-D-Glucuronide

Prodotto controllato

CAS: 20290-09-9

Stability Hygroscopic
Applications A metabolite of Morphine. Analog of Morphine as molecular chameleon with unexpected lipophilicity.Controlled substance.
References Christensen, C.B., et al.: Pharmacol. Toxicol., 60, 75 (1987), Coughtrie, M.W., et al.: Biochem. Pharmacol., 38, 3273 (1989),

Formula: C₂₃H₂₇NO₉

Colore e forma: White To Off-White

Peso molecolare: 461.46

Ref: TR-M652300

Morphine 3-β-D-Glucuronide-D6

Prodotto controllato

CAS: 20290-09-9

Applications A labelled metabolite of Morphine. Analog of Morphine as molecular chameleon with unexpected lipophilicity.Controlled substance.
References Coughtrie, M.W., et al.: Biochem. Pharmacol., 38, 3273 (1989)

Formula: C₂₃H₂₁D₆NO₉

Colore e forma: White To Off-White

Peso molecolare: 467.5

Ref: TR-M652303