CAS 2051527-54-7

DOTA-XYIMSR-01

CAS: 2051527-54-7

DOTA-XYIMSR-01 is a molecular probe targeting CAIX, capable of being labeled with 177Lu for the treatment and localization of malignant gliomas. The uptake of [177Lu]Lu-XYIMSR-01 in U87MG tumors is 6.19% injected dose per gram (% ID/g), with a tumor-to-muscle uptake ratio of 20.14. In an orthotopic glioma model, co-administration with temozolomide significantly enhances survival rates and inhibits tumor growth in mice. DOTA-XYIMSR-01 shows potential for research in the field of cancer treatment.

Formula: C₆₁H₈₈N₁₆O₂₂S₂

Colore e forma: Solid

Peso molecolare: 1461.57

Ref: TM-T206524