CAS 20554-84-1

(-)-Parthenolide

Descrizione:

(-)-Parthenolide è una lattone sesquiterpenica derivata principalmente dalla pianta Tanacetum parthenium, comunemente nota come matricaria. Questo composto è caratterizzato dalla sua unica struttura biciclica, che include un gruppo funzionale lattone. (-)-Parthenolide mostra una gamma di attività biologiche, comprese proprietà antinfiammatorie, antitumorali e antimicrobiche, rendendolo un argomento di interesse nella ricerca farmacologica. È noto per inibire la via di segnalazione del fattore nucleare kappa B (NF-κB), che gioca un ruolo cruciale nell'infiammazione e nella progressione del cancro. Il composto si trova tipicamente in forma liquida incolore o giallo pallido e ha un odore caratteristico. La sua solubilità varia, essendo più solubile nei solventi organici che in acqua. A causa dei suoi potenziali effetti terapeutici, (-)-Parthenolide è oggetto di studio per il suo ruolo nel trattamento di varie condizioni, comprese le emicranie e alcuni tipi di cancro. Tuttavia, sono necessarie ulteriori ricerche per comprendere appieno i suoi meccanismi d'azione e le potenziali applicazioni in medicina.

Formula: C₁₅H₂₀O₃

InChI: InChI=1/C15H20O3/c1-9-5-4-8-15(3)13(18-15)12-11(7-6-9)10(2)14(16)17-12/h5,11-13H,2,4,6-8H2,1,3H3/b9-5+/t11?,12-,13-,15+/m0/s1

InChI key: InChIKey=KTEXNACQROZXEV-PVLRGYAZSA-N

SMILES: C[C@]12[C@@]([C@@]3([C@](C(=C)C(=O)O3)(CC\C(\C)=C\CC1)[H])[H])(O2)[H]

Sinonimi:

• (1aR,4E,10aS,10bS)-1a,5-dimethyl-8-methylidene-2,3,6,7,7a,8,10a,10b-octahydrooxireno[9,10]cyclodeca[1,2-b]furan-9(1aH)-one
• (1aR,4E,7aS,10aS,10bR)-1a,5-dimethyl-8-methylidene-2,3,6,7,7a,8,10a,10b-octahydrooxireno[9,10]cyclodeca[1,2-b]furan-9(1aH)-one
• (1aR,4E,7aS,10aS,10bR)-2,3,6,7,7a,8,10a,10b-Octahydro-1a,5-dimethyl-8-methyleneoxireno[9,10]cyclodeca[1,2-b]furan-9(1aH)-one
• (1aR,4Z,7aS,10aS,10bS)-1a,5-dimethyl-8-methylidene-2,3,6,7,7a,8,10a,10b-octahydrooxireno[9,10]cyclodeca[1,2-b]furan-9(1aH)-one
• (1aR,7aS,10aS,10bR)-1a,5-dimethyl-8-methylidene-2,3,6,7,7a,8,10a,10b-octahydrooxireno[9,10]cyclodeca[1,2-b]furan-9(1aH)-one
• (4E,7aS,10aS)-1a,5-dimethyl-8-methylidene-2,3,6,7,7a,8,10a,10b-octahydrooxireno[9,10]cyclodeca[1,2-b]furan-9(1aH)-one
• (4Z)-1a,5-dimethyl-8-methylidene-2,3,6,7,7a,8,10a,10b-octahydrooxireno[9,10]cyclodeca[1,2-b]furan-9(1aH)-one
• 2,3,6,7,7a,8,10a,10b-Octahydro-1a,5-dimethyl-8-methyleneoxireno(9,10)cyclodeca(1,2-b)furan-9(1aH)-one
• Germacra-1(10),11(13)-dien-12-oic acid, 4,5α-epoxy-6β-hydroxy-, γ-lactone
• Oxireno[9,10]cyclodeca[1,2-b]furan-9(1aH)-one, 2,3,6,7,7a,8,10a,10b-octahydro-1a,5-dimethyl-8-methylene-, (1aR,4E,7aS,10aS,10bR)-
• Parthenolide

Parthenolide

CAS: 20554-84-1

Parthenolide analytical standard provided with chromatographic purity, to be used as reference material for qualitative determination.

Formula: C₁₅H₂₀O₃

Purezza: (HPLC) ≥95%

Colore e forma: Powder

Peso molecolare: 248.33

Ref: 11-3805

PARTHENOLIDE CRS

CAS: 20554-84-1

PARTHENOLIDE CRS

Ref: 41-Y0001838

Parthenolide

CAS: 20554-84-1

Lactones, nesoi

Formula: C₁₅H₂₀O₃

Colore e forma: White Crystalline Powder

Peso molecolare: 248.14124

Ref: 45-1500400

Oxireno[9,10]cyclodeca[1,2-b]furan-9(1aH)-one, 2,3,6,7,7a,8,10a,10b-octahydro-1a,5-dimethyl-8-methylene-, (1aR,4E,7aS,10aS,10bR)-

CAS: 20554-84-1

Formula: C₁₅H₂₀O₃

Purezza: 97%

Colore e forma: Solid

Peso molecolare: 248.3175

Ref: IN-DA002A6V

Parthenolide

CAS: 20554-84-1

Formula: C₁₅H₂₀O₃

Purezza: ≥ 98.0%

Colore e forma: White, off-white or pale yellow-brown powder

Peso molecolare: 248.32

Ref: 7W-GP2300

Parthenolide

CAS: 20554-84-1

Parthenolide

Formula: C₁₅H₂₀O₃

Purezza: By hplc: 99.88% (Typical Value in Batch COA)

Colore e forma: white crystals

Peso molecolare: 248.32g/mol

Ref: 54-BIP0110

Parthenolide

CAS: 20554-84-1

Parthenolide

Purezza: ≥98%

Peso molecolare: 248.32g/mol

Ref: 54-BUP15119

Parthenolide

CAS: 20554-84-1

Formula: C₁₅H₂₀O₃

Purezza: 95%~99%

Peso molecolare: 248.322

Ref: BP-BP1066

Parthenolide

CAS: 20554-84-1

Formula: C₁₅H₂₀O₃

Purezza: >97.0%(HPLC)

Colore e forma: White to Light yellow powder to crystal

Peso molecolare: 248.32

Ref: 3B-P1982

Parthenolide

CAS: 20554-84-1

Parthenolide ((-)-Parthenolide) is a natural sesquiterpene lactone that is an NF-κB and HDAC1 inhibitor with anti-inflammatory effect. Cost-effective and quality-assured.

Formula: C₁₅H₂₀O₃

Purezza: 98.19% - 99.46%

Colore e forma: White To Pale Yellow Crystalline Powder

Peso molecolare: 248.32

Ref: TM-T2140

Parthenolide

CAS: 20554-84-1

Lactone

Formula: C₁₅H₂₀O₃

Purezza: ≥ 90.0 % (HPLC)

Colore e forma: Powder

Peso molecolare: 248.32

Ref: 5G-89255

Parthenolide

CAS: 20554-84-1

Parthenolide is a sesquiterpene lactone, which is a bioactive compound derived from the plant species Tanacetum parthenium, commonly known as feverfew. This compound is primarily isolated from the aerial parts of the plant, where it is found in highest concentrations within the flowers and leaves. Parthenolide exerts its effects through several biochemical pathways, including the inhibition of nuclear factor-kappa B (NF-κB) signaling, which plays a critical role in inflammatory and immune responses. Additionally, it disrupts the activity of certain kinases and modulates the expression of genes involved in cell cycle regulation and apoptosis.

Formula: C₁₅H₂₀O₃

Purezza: Min. 98 Area-%

Colore e forma: White Off-White Powder

Peso molecolare: 248.32 g/mol

Ref: 3D-FP65646

Parthenolide

CAS: 20554-84-1

M02322 - Parthenolide

Formula: C₁₅H₂₀O₃

Purezza: 97%

Colore e forma: Solid

Peso molecolare: 248.322

Ref: 10-M02322