CAS 20633-67-4

calicosina-7-O-beta-D-glucoside

Descrizione:

calicosina-7-O-beta-D-glucoside è un glicoside flavonoide che si verifica naturalmente, derivato principalmente dalle radici delle specie di Astragalus, in particolare Astragalus membranaceus. Questo composto è caratterizzato dalla sua struttura, che consiste in una parte di calicosina legata a una molecola di glucosio tramite un legame beta-glicosidico. Mostra varie attività biologiche, comprese proprietà antiossidanti, anti-infiammatorie e potenziali anticancerogene, rendendolo di interesse nella ricerca farmacologica. Il composto è solubile in solventi polari e la sua stabilità può essere influenzata da fattori come pH e temperatura. calicosina-7-O-beta-D-glucoside è spesso studiato per i suoi potenziali benefici per la salute e applicazioni terapeutiche, in particolare nella medicina tradizionale. La sua presenza in formulazioni a base di erbe evidenzia la sua importanza nella chimica dei prodotti naturali e nell'esplorazione di composti derivati dalle piante per la salute e il benessere. Come molti flavonoidi, può anche contribuire ai profili di colore e sapore delle piante da cui è estratto.

Formula: C₂₂H₂₂O₁₀

InChI: InChI=1/C22H22O10/c1-29-15-5-2-10(6-14(15)24)13-9-30-16-7-11(3-4-12(16)18(13)25)31-22-21(28)20(27)19(26)17(8-23)32-22/h2-7,9,17,19-24,26-28H,8H2,1H3/t17-,19-,20+,21-,22-/m1/s1

Sinonimi:

• 3-(3-Hydroxy-4-methoxyphenyl)-4-oxo-4H-chromen-7-yl beta-D-glucopyranoside
• 4H-1-benzopyran-4-one, 7-(beta-D-glucopyranosyloxy)-3-(3-hydroxy-4-methoxyphenyl)-
• Calycosin-O-Glucopyranoside
• Calycosin 7-O-Glucoside
• Calycosin 7-O-β-D-glucopyranoside

Calycosin 7-O-β-D-Glucopyranoside (3-(3-Hydroxy-4-methoxyphenyl)-4-oxo-4H-chromen7-yl β-D-glucopyranoside)

CAS: 20633-67-4

Other glycosides, natural or reproduced by synthesis, and their salts, ethers, esters and other derivatives

Formula: C₂₂H₂₂O₁₀

Colore e forma: Powder

Peso molecolare: 446.1213

Ref: 45-1087483

4H-1-Benzopyran-4-one, 7-(β-D-glucopyranosyloxy)-3-(3-hydroxy-4-methoxyphenyl)-

CAS: 20633-67-4

Formula: C₂₂H₂₂O₁₀

Purezza: 98%

Colore e forma: Solid

Peso molecolare: 446.4041

Ref: IN-DA002IGF

Calycosin-7-O-β-D-glucoside

CAS: 20633-67-4

Calycosin-7-O-β-D-glucoside

Purezza: ≥98%

Peso molecolare: 446.4g/mol

Ref: 54-BUP07155

calycosin-7-O-β-D-glucoside

CAS: 20633-67-4

Formula: C₂₂H₂₂O₁₀

Peso molecolare: 446.41

Ref: 7W-GY4388

calycosin-7-O-β-D-glucoside

CAS: 20633-67-4

Calycosin-7-O-β-d-glucoside(CG) treatment can significantly reduce infarct volume, histological damage and BBB permeability in the in vivo MCAO ischemia–reperfusion rat model; inhibit the expression and activities of MMPs, and secure the expression of cav-1 and tight junction proteins in the microvessels isolated from ischemic rat cortex; scavenge NO, inhibit the activities of MMP-2 and MMP-9, and attenuate cell death in the in vitro cultured brain microvascular endothelial cells under OGD condition; thus CG could protect BBB integrity in experimental cerebral ischemia–reperfusion injury via regulating NO/cav-1/MMPs pathway.

Formula: C₂₂H₂₂O₁₀

Purezza: 95%~99%

Colore e forma: Powder

Peso molecolare: 446.408

Ref: BP-BP0306

Calycosin 7-glucoside

CAS: 20633-67-4

Natural glycoside

Formula: C₂₂H₂₂O₁₀

Purezza: ≥ 95.0 % (HPLC)

Colore e forma: Powder

Peso molecolare: 446.41

Ref: 5G-82492

Calycosin-7-O-β-D-glucoside

CAS: 20633-67-4

Calycosin-7-O-β-D-glucoside is a flavonoid glycoside, which is primarily derived from the root of Astragalus membranaceus, a plant widely used in traditional Chinese medicine. This compound is characterized by its antioxidative and anti-inflammatory activities, mediated through modulation of various signaling pathways in the body, such as the MAPK and NF-κB pathways. It plays a significant role in scavenging free radicals and inhibiting inflammatory mediators, thus contributing to cellular protection and reducing oxidative stress.

Formula: C₂₂H₂₂O₁₀

Purezza: Min. 95%

Colore e forma: White Powder

Peso molecolare: 446.4 g/mol

Ref: 3D-MC44349

Calycosin-7-O-β-D-glucoside

CAS: 20633-67-4

Calycosin-7-O-β-D-glucoside (calycosin-7-O-beta-D-glucopyranoside) possesses a protective effect on rat hepatocytes, an inhibitory effect on COX-2 activity.

Formula: C₂₂H₂₂O₁₀

Purezza: 98% - 99.981%

Colore e forma: Solid

Peso molecolare: 446.4

Ref: TM-T3388

Calycosin 7-O-β-D-glucoside

Prodotto controllato

CAS: 20633-67-4

Applications Calycosin 7-O-β-D-glucoside is one of seven constituent in Guanjiekang (GJK) that is formed by five medicinal herbs that is used for the rheumatoid arthritis (RA).
References Wu, J., et al.: Mol., 21, 1732/1-1732/12 (2016)

Formula: C₂₂H₂₂O₁₀

Colore e forma: Neat

Peso molecolare: 446.40

Ref: TR-C148935