CAS 206449-93-6

2-[(2-Furilmetil)sulfinil]-N-[(2Z)-4-[[4-(1-piperidinilmetil)-2-piridinil]ossi]-2-buten-1-il]acetamide

Descrizione:

La sostanza chimica nota come 2-[(2-Furilmetil)sulfinil]-N-[(2Z)-4-[[4-(1-piperidinilmetil)-2-piridinil]ossi]-2-buten-1-il]acetamide, con il numero CAS 206449-93-6, è caratterizzata dalla sua complessa struttura molecolare, che include un anello di furanos, un gruppo sulfinile e un moiety di piperidina. Questo composto presenta proprietà tipiche delle sulfinammidi, inclusa una potenziale attività biologica dovuta alle sue caratteristiche strutturali che possono interagire con vari bersagli biologici. La presenza dell'anello di furanos suggerisce una possibile reattività e partecipazione in varie reazioni chimiche, mentre i componenti di piperidina e piridina possono contribuire alle sue proprietà farmacologiche. La stereochimica specifica del composto, indicata dalla configurazione (2Z), può influenzare la sua attività biologica e interazioni. In generale, questa sostanza è di interesse nella chimica medicinale e nella farmacologia, potenzialmente fungendo da composto guida per ulteriori sviluppi in applicazioni terapeutiche. Tuttavia, sarebbero necessari studi dettagliati per chiarire completamente le sue proprietà e potenziali usi.

Formula: C₂₂H₂₉N₃O₄S

InChI: InChI=1/C22H29N3O4S/c26-21(18-30(27)17-20-7-6-14-28-20)23-9-2-5-13-29-22-15-19(8-10-24-22)16-25-11-3-1-4-12-25/h2,5-8,10,14-15H,1,3-4,9,11-13,16-18H2,(H,23,26)/b5-2-

InChI key: InChIKey=KMZQAVXSMUKBPD-DJWKRKHSNA-N

SMILES: C(C=1C=C(OC/C=C\CNC(CS(CC2=CC=CO2)=O)=O)N=CC1)N3CCCCC3

Sinonimi:

• Acetamide, 2-[(2-furanylmethyl)sulfinyl]-N-[(2Z)-4-[[4-(1-piperidinylmethyl)-2-pyridinyl]oxy]-2-buten-1-yl]-
• 2-[(2-Furanylmethyl)sulfinyl]-N-[(2Z)-4-[[4-(1-piperidinylmethyl)-2-pyridinyl]oxy]-2-buten-1-yl]acetamide
• Acetamide, 2-[(2-furanylmethyl)sulfinyl]-N-[4-[[4-(1-piperidinylmethyl)-2-pyridinyl]oxy]-2-butenyl]-, (Z)-
• Acetamide, 2-[(2-furanylmethyl)sulfinyl]-N-[(2Z)-4-[[4-(1-piperidinylmethyl)-2-pyridinyl]oxy]-2-butenyl]-
• (±)-Lafutidine
• rac Lafutidine
• (Z)-Lafutidine
• (Z)-FRG-8813

Acetamide, 2-[(2-furanylmethyl)sulfinyl]-N-[(2Z)-4-[[4-(1-piperidinylmethyl)-2-pyridinyl]oxy]-2-buten-1-yl]-

CAS: 206449-93-6

Formula: C₂₂H₂₉N₃O₄S

Purezza: 97%

Colore e forma: Solid

Peso molecolare: 431.5484

Ref: IN-DA002IHU

(Z)-2-((Furan-2-ylmethyl)sulfinyl)-N-(4-((4-(piperidin-1-ylmethyl)pyridin-2-yl)oxy)but-2-en-1-yl)acetamide

CAS: 206449-93-6

(Z)-2-((Furan-2-ylmethyl)sulfinyl)-N-(4-((4-(piperidin-1-ylmethyl)pyridin-2-yl)oxy)but-2-en-1-yl)acetamide

Purezza: 97%

Peso molecolare: 431.56g/mol

Ref: 54-OR1059107

rac Lafutidine

Prodotto controllato

CAS: 206449-93-6

Applications Lafutidine is a second generation histamine H2-receptor antagonist. Lafutidine is used as an antiulcerative.
References Onodera, S., et al.: Jpn. J. Pharmacol., 68, 161 (1995), Umeda, M., et al.: J. Gastroenterol. Heoatol., 14, 859 (1999), Ajioka, H., et al.: Pharmacology, 61, 83 (2000),

Formula: C₂₂H₂₉N₃O₄S

Colore e forma: White To Light Yellow

Peso molecolare: 431.55

Ref: TR-L168500

rac Lafutidine

CAS: 206449-93-6

Lafutidine is a proton pump inhibitor that belongs to the class of H1 receptor antagonists. It is a potent and long lasting H1 receptor antagonist with a long half-life, which may be due to its ability to form a stable covalent bond with the active site of the enzyme. Lafutidine has been shown to inhibit gastric acid secretion in two-way crossover trials, reducing disease activity in patients with infectious diseases. It was also shown to increase water permeability in dextran sulfate sodium-induced ileitis models, although toxicity studies were not performed. Molecular docking analysis showed that lafutidine binds to the human serum albumin (HSA) binding site on the enzyme's active site, suggesting that it may have toxicological properties.

Formula: C₂₂H₂₉N₃O₄S

Purezza: Min. 95%

Peso molecolare: 431.55 g/mol

Ref: 3D-FR27533