CAS 20830-75-5: Digossina

Descrizione: Digossina è un glicoside cardiaco derivato dalle foglie della pianta di digitale (Digitalis purpurea) ed è utilizzato principalmente nel trattamento di varie condizioni cardiache, in particolare la fibrillazione atriale e l'insufficienza cardiaca. Funziona inibendo la pompa ATPasi sodio-potassio, portando a un aumento delle concentrazioni di calcio intracellulare, il che migliora la contrattilità cardiaca. Digossina è caratterizzato da una finestra terapeutica relativamente stretta, il che significa che la differenza tra una dose efficace e una dose tossica è piccola, richiedendo un attento monitoraggio dei livelli sierici nei pazienti. Viene tipicamente somministrato per via orale o endovenosa ed è noto per i suoi potenziali effetti collaterali, che possono includere disturbi gastrointestinali, cambiamenti visivi e aritmie. La sostanza ha una formula molecolare di C41H64O14 e un peso molecolare di circa 780,94 g/mol. La farmacocinetica di Digossina è influenzata da fattori come la funzione renale e le interazioni con altri farmaci, rendendo essenziale una dosaggio personalizzato per un uso sicuro ed efficace.

Formula: C₄₁H₆₄O₁₄

InChI: InChI=1S/C41H64O14/c1-19-36(47)28(42)15-34(50-19)54-38-21(3)52-35(17-30(38)44)55-37-20(2)51-33(16-29(37)43)53-24-8-10-39(4)23(13-24)6-7-26-27(39)14-31(45)40(5)25(9-11-41(26,40)48)22-12-32(46)49-18-22/h12,19-21,23-31,33-38,42-45,47-48H,6-11,13-18H2,1-5H3/t19-,20-,21-,23-,24+,25-,26-,27+,28+,29+,30+,31-,33+,34+,35+,36-,37-,38-,39+,40+,41+/m1/s1

InChI key: InChIKey=LTMHDMANZUZIPE-PUGKRICDSA-N

SMILES: O=C1OCC(=C1)C2CCC3(O)C4CCC5CC(OC6OC(C)C(OC7OC(C)C(OC8OC(C)C(O)C(O)C8)C(O)C7)C(O)C6)CCC5(C)C4CC(O)C23C

Sinonimi:

• (3beta,5beta,12beta)-3-{[2,6-dideoxy-beta-D-ribo-hexopyranosyl-(1->4)-2,6-dideoxy-beta-D-ribo-hexopyranosyl-(1->4)-2,6-dideoxy-beta-D-ribo-hexopyranosyl]oxy}-12,14-dihydroxycard-20(22)-enolide
• (3beta,5beta,8xi,9xi,12beta)-3-{[2,6-dideoxy-beta-D-ribo-hexopyranosyl-(1->4)-2,6-dideoxy-beta-D-ribo-hexopyranosyl-(1->4)-2,6-dideoxy-beta-D-ribo-hexopyranosyl]oxy}-12,14-dihydroxycard-20(22)-enolide
• (3β,5β,12β)-3-[(O-2,6-Dideoxy-β-<span class="text-smallcaps">D</smallcap>-ribo-hexopyranosyl-(1→4)-O-2,6-dideoxy-β-<smallcap>D</smallcap>-ribo-hexopyranosyl-(1→4)-2,6-dideoxy-β-<smallcap>D</span>-ribo-hexopyranosyl)oxy]-12,14-dihydroxycard-20(22)-enolide
• 12β-Hydroxydigitoxin
• Card-20(22)-enolide, 3-[(O-2,6-dideoxy-β-<span class="text-smallcaps">D</smallcap>-ribo-hexopyranosyl-(1→4)-O-2,6-dideoxy-β-<smallcap>D</smallcap>-ribo-hexopyranosyl-(1→4)-2,6-dideoxy-β-<smallcap>D</span>-ribo-hexopyranosyl)oxy]-12,14-dihydroxy-, (3β,5β,12β)-
• Card-20(22)-enolide, 3-[(O-2,6-dideoxy-β-D-ribo-hexopyranosyl-(1→4)-O-2,6-dideoxy-β-D-ribo-hexopyranosyl-(1→4)-2,6-dideoxy-β-D-ribo-hexopyranosyl)oxy]-12,14-dihydroxy-, (3β,5β,12β)-
• Cardigox
• Cardiogoxin
• Cardioxin
• Cardixin
• Cardoxin
• Chloroformic digitalin
• Coragoxine
• Cordioxil
• Davoxin
• Digacin
• Digicor
• Digitek
• Digitoxin, 12β-hydroxy-
• Digomal
• Digon
• Digosin
• Digoxin (FDA)
• Digoxin Nativelle
• Digoxina
• Digoxine
• Dilanacin
• Dixina
• Dokim
• Dynamos
• Eudigox
• Fargoxin
• Grexin
• Homolle's digitalin
• Lanacordin
• Lanacrist
• Lanicor
• Lanikor
• Lanocardin
• Lanorale
• Lanoxicaps
• Lanoxin
• Lanoxin PG
• Lenoxicaps
• Lenoxin
• Longdigox
• Mapluxin
• Natigoxin
• NeoDioxanin
• Novodigal-Amp.
• Nsc 95100
• Purgoxin
• Rougoxin
• Stillacor
• Toloxin
• Vanoxin
• (3β,5β,12β)-3-[(O-2,6-Dideoxy-β-D-ribo-hexopyranosyl-(1→4)-O-2,6-dideoxy-β-D-ribo-hexopyranosyl-(1→4)-2,6-dideoxy-β-D-ribo-hexopyranosyl)oxy]-12,14-dihydroxycard-20(22)-enolide
• Digoxin

Digoxin, 96%

CAS: 20830-75-5

Digoxin is used in several cardiac pathologies such as atrial fibrillation and heart failure. This …

• Formula: C₄₁H₆₄O₁₄
• Purezza: 96%
• Colore e forma: Powder, White
• Peso molecolare: 780.95

Digoxin

CAS: 20830-75-5

Digoxin analytical standard provided with chromatographic purity, to be used as reference material for qualitative …

• Formula: C₄₁H₆₄O₁₄
• Purezza: (HPLC) ≥95%
• Colore e forma: Powder
• Peso molecolare: 780.95

Digoxin CRS

CAS: 20830-75-5

• Formula: C₄₁H₆₄O₁₄
• Colore e forma: White. Whitish. Powder.
• Peso molecolare: 780.9385

Digoxin for peak identification CRS

CAS: 20830-75-5

• Formula: C₄₁H₆₄O₁₄
• Peso molecolare: 780.9385

Digoxin RS

CAS: 20830-75-5

• Formula: C₄₁H₆₄O₁₄
• Peso molecolare: 780.9385

Digoxin

CAS: 20830-75-5

Other glycosides, natural or reproduced by synthesis, a

• Formula: C₄₁H₆₄O₁₄
• Colore e forma: White Translucent Crystalline Powder Crystals
• Peso molecolare: 780.94

Digoxin, USP grade

CAS: 20830-75-5

• Formula: C₄₁H₆₄O₁₄
• Peso molecolare: 780.95

Digoxin

CAS: 20830-75-5

• Purezza: 96%
• Colore e forma: White Solid
• Peso molecolare: 780.94g/mol

Digoxin-d3

CAS: 127299-95-0 20830-75-5

• Formula: C₄₁H₆₁D₃O₁₄
• Colore e forma: Off-White Solid
• Peso molecolare: 783.98

Digoxin

CAS: 20830-75-5

• Formula: C₄₁H₆₄O₁₄
• Colore e forma: White To Off-White Solid
• Peso molecolare: 780.95

Digoxin

CAS: 20830-75-5

• Formula: C₄₁H₆₄O₁₄
• Purezza: ≥ 94.5% (anhydrous basis)
• Colore e forma: White to off-white powder
• Peso molecolare: 780.95

Digoxin

CAS: 20830-75-5

Digoxin is a classical Na,K-ATPase inhibitor, with selectivity for the α2β3 isoform over the common …

• Formula: C₄₁H₆₄O₁₄
• Purezza: 95%~99%
• Peso molecolare: 780.949

Digoxin, 95%

CAS: 20830-75-5

This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. …

• Formula: C₄₁H₆₄O₁₄
• Purezza: 95%
• Colore e forma: Crystalline powder or crystals, White to off-white
• Peso molecolare: 780.95

Digoxin

CAS: 20830-75-5

• Formula: C₄₁H₆₄O₁₄
• Colore e forma: Neat
• Peso molecolare: 780.94

Digoxin

CAS: 20830-75-5

• Formula: C₄₁H₆₄O₁₄
• Purezza: >96.0%(HPLC)
• Colore e forma: White to Almost white powder to crystaline
• Peso molecolare: 780.95

Digoxin

CAS: 20830-75-5

• Formula: C₄₁H₆₄O₁₄
• Colore e forma: Neat
• Peso molecolare: 780.94

Digoxin RS

CAS: 20830-75-5

• Colore e forma: Colorless To White

Digoxin

CAS: 20830-75-5

Applications Cardiotonic. Not a dangerous good if item is equal to or less than 1g/ml …

• Formula: C₄₁H₆₄O₁₄
• Colore e forma: White
• Peso molecolare: 780.94

12β-Hydroxydigitoxin

CAS: 20830-75-5

Please enquire for more information about 12beta-Hydroxydigitoxin including the price, delivery time and more detailed …

• Formula: C₄₁H₆₄O₁₄
• Peso molecolare: 780.95 g/mol

Digoxin

CAS: 20830-75-5

Digoxin and its derivatives are the most widely used as cardiac glycosides. Digoxin is isolated …

• Formula: C₄₁H₆₄O₁₄
• Purezza: Min. 95%
• Colore e forma: Powder
• Peso molecolare: 780.94 g/mol

Digoxin extrapure, 95%

CAS: 20830-75-5

• Formula: C₄₁H₆₄O₁₄
• Purezza: min. 95%
• Colore e forma: White to off white, Crystalline powder, Clear
• Peso molecolare: 780.94