CAS 20874-52-6

Saikosaponina D

Descrizione:

Saikosaponina D è una saponina triterpenoide derivata principalmente dalle radici della pianta Bupleurum falcatum, comunemente nota per il suo utilizzo nella medicina tradizionale. È caratterizzata dalla sua struttura complessa, che include uno scheletro simile a uno steroide con vari moietti di zucchero attaccati, contribuendo alla sua attività biologica. Saikosaponina D presenta una gamma di proprietà farmacologiche, tra cui effetti anti-infiammatori, epatoprotettivi e immunomodulatori. Si pensa che il suo meccanismo d'azione coinvolga la modulazione di varie vie di segnalazione, comprese quelle relative all'apoptosi e alla proliferazione cellulare. Inoltre, Saikosaponina D è stata studiata per le sue potenziali proprietà anticancro, mostrando promesse nell'inibire la crescita tumorale in varie linee cellulari di cancro. La sostanza è tipicamente solubile in acqua e solventi organici, rendendola adatta per vari processi di estrazione e formulazione. Come molti composti naturali, ulteriori ricerche sono in corso per chiarire completamente il suo potenziale terapeutico e i meccanismi d'azione, oltre a esplorare la sua sicurezza e efficacia nelle applicazioni cliniche.

Formula: C₄₂H₆₈O₁₃

InChI: InChI=1S/C42H68O13/c1-21-28(46)33(55-34-31(49)30(48)29(47)22(18-43)53-34)32(50)35(52-21)54-27-10-11-37(4)23(38(27,5)19-44)8-12-39(6)24(37)9-13-42-25-16-36(2,3)14-15-41(25,20-51-42)26(45)17-40(39,42)7/h9,13,21-35,43-50H,8,10-12,14-20H2,1-7H3/t21-,22-,23-,24-,25?,26-,27+,28+,29-,30+,31-,32-,33+,34+,35+,37+,38+,39-,40+,41-,42+/m1/s1

InChI key: InChIKey=KYWSCMDFVARMPN-VFDNYBEVSA-N

SMILES: C[C@]12[C@@]3(C4([C@@](CO3)([C@H](O)C1)CCC(C)(C)C4)[H])C=C[C@]5([C@@]2(C)CC[C@@]6([C@]5(C)CC[C@H](O[C@H]7[C@H](O)[C@@H](O[C@@H]8O[C@H](CO)[C@@H](O)[C@H](O)[C@H]8O)[C@@H](O)[C@@H](C)O7)[C@]6(CO)C)[H])[H]

Sinonimi:

• (3beta,13alpha,16alpha,17alpha)-16,23-dihydroxy-13,28-epoxyolean-11-en-3-yl 6-deoxy-3-O-beta-D-glucopyranosyl-beta-D-galactopyranoside
• (3beta,16alpha)-16,23-Dihydroxy-13,28-epoxyolean-11-en-3-yl 6-deoxy-3-O-beta-D-glucopyranosyl-beta-D-galactopyranoside
• (3β,4α,16α)-13,28-Epoxy-16,23-dihydroxyolean-11-en-3-yl 6-deoxy-3-O-β-<span class="text-smallcaps">D</smallcap>-glucopyranosyl-β-<smallcap>D</span>-galactopyranoside
• beta-D-galactopyranoside, (3beta,16alpha)-13,28-epoxy-16,23-dihydroxyolean-11-en-3-yl 6-deoxy-3-O-beta-D-glucopyranosyl-
• sailkosaponin D
• β-<span class="text-smallcaps">D</smallcap>-Galactopyranoside, (3β,4α,16α)-13,28-epoxy-16,23-dihydroxyolean-11-en-3-yl 6-deoxy-3-O-β-<smallcap>D</span>-glucopyranosyl-
• Saikosaponin D
• (3β,4α,16α)-13,28-Epoxy-16,23-dihydroxyolean-11-en-3-yl 6-deoxy-3-O-β-D-glucopyranosyl-β-D-galactopyranoside
• β-D-Galactopyranoside, (3β,4α,16α)-13,28-epoxy-16,23-dihydroxyolean-11-en-3-yl 6-deoxy-3-O-β-D-glucopyranosyl-

β-D-Galactopyranoside, (3β,4α,16α)-13,28-epoxy-16,23-dihydroxyolean-11-en-3-yl 6-deoxy-3-O-β-D-glucopyranosyl-

CAS: 20874-52-6

Formula: C₄₂H₆₈O₁₃

Purezza: %

Colore e forma: Solid

Peso molecolare: 780.9815

Ref: IN-DA002JVD

Saikosaponin D

CAS: 20874-52-6

Saikosaponin D

Purezza: ≥98%

Peso molecolare: 780.98g/mol

Ref: 54-BUP10684

Saikosaponin D

CAS: 20874-52-6

Formula: C₄₂H₆₈O₁₃

Peso molecolare: 780.98

Ref: 7W-GC1918

Saikosaponin D

CAS: 20874-52-6

SaikosaponinD (SSd) is a major triterpenoid saponin derivative from Radix bupleuri, which has been long used in Chinese traditional medicine for treatment of various inflammation-related diseases; it shows potent anti-inflammatory activity through inhibitory effects on NF-κB activation and thereby on iNOS, COX-2 and pro-inflammatory cytokines.

Formula: C₄₂H₆₈O₁₃

Purezza: 95%~99%

Colore e forma: Powder

Peso molecolare: 780.993

Ref: BP-BP1242

Saikosaponin D

CAS: 20874-52-6

Formula: C₄₂H₆₈O₁₃

Purezza: >98.0%(HPLC)

Colore e forma: White to Almost white powder to crystal

Peso molecolare: 780.99

Ref: 3B-A3405

Saikosaponin D

CAS: 20874-52-6

Saikosaponin D is a novel SERCA inhibitor by inhibiting NF-κB and STAT3 signaling to protect against acetaminophen-induced hepatotoxicity.

Formula: C₄₂H₆₈O₁₃

Purezza: 98.34% - 99.73%

Colore e forma: White Powder

Peso molecolare: 780.98

Ref: TM-T3913

Saikosaponin d

CAS: 20874-52-6

Natural glycoside

Formula: C₄₂H₆₈O₁₃

Purezza: ≥ 90.0 % (HPLC)

Colore e forma: Powder

Peso molecolare: 781

Ref: 5G-89527

Saikosaponin D

CAS: 20874-52-6

Saikosaponin D is a bioactive compound, specifically a triterpenoid saponin, which is derived from the roots of Bupleurum species, plants commonly used in traditional Chinese medicine. Its mode of action involves modulating key pathways in inflammation and apoptosis. This compound targets cellular mechanisms by interacting with inflammatory mediators and apoptotic proteins, thereby influencing immune responses and cellular survival.

Formula: C₄₂H₆₈O₁₃

Purezza: Min. 98 Area-%

Colore e forma: White Powder

Peso molecolare: 780.98 g/mol

Ref: 3D-OS09508

Saikosaponin D

Prodotto controllato

CAS: 20874-52-6

Applications Saikosaponin D is an inhibitor of proliferation of human prostate cancer cells through arresting the cell cycle.
References Yao, M. et al.: Mol. Med. Rep., 10, 365 (2014); Li, Z. et al.: Prog. Neuro-Psychopharm. Biol. Psych., 53, 80 (2014);

Formula: C₄₂H₆₈O₁₃

Colore e forma: Neat

Peso molecolare: 780.98

Ref: TR-S083915