CAS 2089065-77-8

Macitentan Sulfamide Dimer (N,N''-[1,2-Ethanediylbis[oxy[5-(4-bromophenyl)-6,4-pyrimidinediyl]]]bis[N'-propylsulfamide])

CAS: 2089065-77-8

Compounds containing a pyrimidine ring, whether or not hydrogenated, or piperazine ring in the structure, nesoi

Formula: C₂₈H₃₂Br₂N₈O₆S₂

Colore e forma: Off-White Solid

Peso molecolare: 798.0253

Ref: 45-1A05660

Macitentan Impurity 4

CAS: 2089065-77-8

Formula: C₂₈H₃₂Br₂N₈O₆S₂

Colore e forma: White To Off-White Solid

Peso molecolare: 800.54

Ref: 4Z-M-128008

O-Desbromo-pyrimidinyl O-[6-N-(N'-propyl)sulfamido-5-(4-bromophenyl)pyrimidin-4-yl] Macitentan

Prodotto controllato

CAS: 2089065-77-8

Applications O-Desbromo-pyrimidinyl O-[6-N-(N'-propyl)sulfamido-5-(4-bromophenyl)pyrimidin-4-yl] Macitentan is an impurity of Macitentan (M105005); a dual orally active and potent endothelin receptor antagonist used for pulmonary arterial hypertension.
References Emoto, N. Ensho to Men'eki, 20, 487 (2012); Bruderer, S., et al.: Xenobiotica, 42, 901 (2012); Bolli, M.H., et al.: J. Med. Chem., 55, 7849 (2012)

Formula: C₂₈H₃₂Br₂N₈O₆S₂

Colore e forma: Neat

Peso molecolare: 800.54

Ref: TR-D282005

Macitentan Dimer Impurity

CAS: 2089065-77-8

Formula: C₂₈H₃₂Br₂N₈O₆S₂

Peso molecolare: 800.54

Ref: ST-EA-CP-M5014