CAS 2089123-71-5

Ethyl N-(3-Chloro-6,11-dihydro-6-methyl-5,5-dioxidodibenzo[c,f][1,2]thiazepin-11-yl)-amino-propanoate

Prodotto controllato

CAS: 2089123-71-5

Applications Ethyl N-(3-Chloro-6,11-dihydro-6-methyl-5,5-dioxidodibenzo[c,f][1,2]thiazepin-11-yl)-amino-propanoate is used in the preparation of dibenzothiazepines as opioid receptor agonists; Also, it is an intermediate used in the synthesis of N-(3-Chloro-6,11-dihydro-6-methyl-5,5-dioxidodibenzo[c,f][1,2]thiazepin-11-yl)-β-alanine (C424340), which is a metabolite of Tianeptine (T436800), a tricyclic compound with psychostimulant, anti-ulcer and anti-emetic properties. Antidepressant.
References Kruegel, A., et al.: PCT Int. Appl. (2017) WO 2017049158; Malen, C., et al.: Experientia, 28, 811 (1972), Safa, A., et al.: J. Biol. Chem., 262, 7884 (1987), Ford, J.M., et al.: Pharmacol. Rev., 42, 155, (1990), Pierre, A., et a.: Cancer Res., 51, 2312 (1991), Nair, M. et al.: Analyst, 123, 2267 (1998)

Formula: C₁₉H₂₁ClN₂O₄S

Colore e forma: Neat

Peso molecolare: 408.899

Ref: TR-E903735

Ethyl N-(3-Chloro-6,11-dihydro-6-methyl-5,5-dioxidodibenzo[c,f][1,2]thiazepin-11-yl)-amino-propanoate-d4

Prodotto controllato

CAS: 2089123-71-5

Formula: C₁₉D₄H₁₇ClN₂O₄S

Colore e forma: Neat

Peso molecolare: 412.924

Ref: TR-E903737