CAS 2108554-00-1

NG25 trihydrochloride

CAS: 2108554-00-1

NG25 trihydrochloride: kinase inhibitor for MAP4K2, TAK1, Src, LYN, Abl, CSK, FER, p38α; blocks TNF-α signals; impedes IFN secretion; anti-cancer properties.

Formula: C₂₉H₃₃Cl₃F₃N₅O₂

Colore e forma: Solid

Peso molecolare: 646.96

Ref: TM-T69898

NG 25 trihydrochloride

CAS: 2108554-00-1

NG 25 trihydrochloride is a potent and selective inhibitor of the nicotinic acetylcholine receptor. It has been shown to inhibit the activity of the receptor in vitro, with IC50 values of 1.1 nM against α7-nicotinic acetylcholine receptors and 4.3 μM against β2-nicotinic acetylcholine receptors. NG 25 trihydrochloride has also been shown to be an agonist at α7-nicotinic acetylcholine receptors and a partial agonist at β2-nicotinic acetylcholine receptors in vivo. This product may be used as a research tool for investigating the role of ion channels in cell biology.

Formula: C₂₇H₂₄N₂O₅

Purezza: Min. 95%

Peso molecolare: 456.5 g/mol

Ref: 3D-IJD55400