CAS 2117405-13-5

3-(6-Fluoropyridin-3-yl)-2-[4-(4-methyl-4H-1,2,4-triazol-3-yl)piperidin-1-yl]pyridine

CAS: 2117405-13-5

3-(6-Fluoropyridin-3-yl)-2-[4-(4-methyl-4H-1,2,4-triazol-3-yl)piperidin-1-yl]pyridine

Purezza: 95%

Peso molecolare: 338.39g/mol

Ref: 54-PC1007087

SEN177

CAS: 2117405-13-5

SEN177 shows the potential in the research of Huntington's disease that is a potent inhibitor of glutaminyl cyclase (QPCT) with an IC 50 of 0.013μM for glutaminyl-peptide cyclotransferase-like (QPCTL). The Ki value of SEN177 for human glutaminyl cyclase (hQC) is 20 nM. SEN177 significantly reduces the early stages of mutant HTT oligomerisation and reduces the percentage of neurons with Q80 aggregates [1].

Formula: C₁₈H₁₉FN₆

Colore e forma: Solid

Peso molecolare: 338.38

Ref: TM-T61063

SEN 177

CAS: 2117405-13-5

Inhibitor of glutaminyl cyclase QPCT

Formula: C₁₈H₁₉FN₆

Purezza: Min. 95%

Peso molecolare: 338.38 g/mol

Ref: 3D-BS170200