CAS 2130750-59-1

(3aR,4R,5R,7S,8S,9R,9aS,12R)-8-Hydroxy-4,7,9,12-tetramethyl-3-oxo-7-vinyldecahydro-4,9a-propanocyclopenta[8]annulen-5-yl 2-((7-fluor o-1-hydroxy-1,3-dihydrobenzo[C][1,2]-oxaborol-6-yl)oxy)acetate

CAS: 2130750-59-1

(3aR,4R,5R,7S,8S,9R,9aS,12R)-8-Hydroxy-4,7,9,12-tetramethyl-3-oxo-7-vinyldecahydro-4,9a-propanocyclopenta[8]annulen-5-yl 2-((7-fluoro-1-hydroxy-1,3-dihydrobenzo[C][1,2]-oxaborol-6-yl)oxy)acetate is a novel antifungal compound derived from boron chemistry, representing a new class of therapeutic agents in the field of antifungal treatments. The compound primarily originates from the synthesis and refinement of boron-based molecular scaffolds, yielding a structure capable of disrupting fungal growth through a unique mode of action. It functions by inhibiting the fungal enzyme leucyl-tRNA synthetase, which is crucial in protein synthesis and thus vital for fungal cell survival and proliferation. By targeting this specific enzyme, the compound effectively halts the production of essential proteins, leading to the cessation of fungal growth and eventual cell death. The primary application of this compound is in the treatment of a range of fungal infections, particularly those that are resistant to conventional antifungal drugs, offering a potent alternative in clinical settings. The application of this compound spans both topical and systemic treatments, addressing a critical need for more effective antifungal therapies.

Formula: C₂₉H₃₈BFO₇

Purezza: Min. 95%

Peso molecolare: 528.4 g/mol

Ref: 3D-FKD75059

AN11251

CAS: 2130750-59-1

AN11251: oral anti-Wolbachia, treats onchocerciasis & lymphatic filariasis, EC50=1.5nM (LDW1), 15nM (C6/36).

Formula: C₂₉H₃₈BFO₇

Purezza: 98%

Colore e forma: Solid

Peso molecolare: 528.42

Ref: TM-T14285