CAS 2141974-01-6

Benzenepropanamine, 4-methoxy-N-[(1S)-1-methyl-2-phenylethyl]-

Formula: C₁₉H₂₅NO

Sinonimi:

• Benzenepropanamine, 4-methoxy-N-[(1S)-1-methyl-2-phenylethyl]-

GZ-11608

CAS: 2141974-01-6

GZ-11608, a selective and potent inhibitor of vesicular monoamine transporter-2 (VMAT2), presents a high affinity with a Ki value of 25 nM. It effectively reduces dopamine release induced by methamphetamine from isolated synaptic vesicles in brain dopaminergic neurons. GZ-11608 also demonstrates rapid penetration into the brain without exhibiting neurotoxicity, making it a valuable compound for researching methamphetamine use disorder [1].

Formula: C₁₉H₂₅NO

Colore e forma: Solid

Peso molecolare: 283.41

Ref: TM-T86539