CAS 2143010-83-5

AZD-5991 Racemate

CAS: 2143010-83-5

AZD-5991 Racemate

Purezza: ≥95%

Peso molecolare: 672.26g/mol

Ref: 54-BUP21544

AZD5991

CAS: 2143010-83-5

AZD5991 is a gossypol derivative that has potent antitumor activity and is an inhibitor of the apoptosis pathway. AZD5991 inhibits the expression of MCL-1, which plays a key role in the regulation of mitochondrial membrane depolarization. It also inhibits cyclin D2, which is important for cell cycle progression, and pd-l1, which regulates T cell activation. These activities indicate that AZD5991 may be a potential anticancer agent for treatment of myeloid leukemia cells or T-cell lymphomas. The enantiomer form of AZD5991 has been shown to be more potent than the racemic mixture in inducing apoptosis in cancerous cells.

Formula: C₃₅H₃₄ClN₅O₃S₂

Purezza: Min. 95%

Peso molecolare: 672.3 g/mol

Ref: 3D-TKD01083

AZD-5991 Racemate

CAS: 2143010-83-5

AZD-5991 Racemate is the racemate of AZD-5991. (Rac)-AZD-5991 is a novel Mcl-1 inhibitor induces upregulation of BCL2,BCL-XL, CMYC and MCL1 in AML cell lines.

Formula: C₃₅H₃₄ClN₅O₃S₂

Colore e forma: Solid

Peso molecolare: 672.26

Ref: TM-T10434L