CAS 2144425-14-7

IACS-8968

CAS: 2144425-14-7

IACS-8968 is an imidazole derivative that inhibits the enzyme IDO (indoleamine 2,3-dioxygenase) and kynurenine hydroxylase, which are enzymes involved in the metabolism of tryptophan. This leads to a decrease in the production of kynurenine, which has been shown to have anticancer effects. IACS-8968 can also be used as a chemical inhibitor with other anticancer drugs such as monoclonal antibody or cytotoxic drugs. IACS-8968 has synergistic anticancer properties when combined with other agents.

Formula: C₁₇H₁₈F₃N₅O₂

Purezza: Min. 95%

Peso molecolare: 381.35 g/mol

Ref: 3D-UKD42514

IACS-8968

CAS: 2144425-14-7

IACS-8968 is a dual IDO and TDO inhibitor (pIC50s: 6.43 for IDO and <5 for TDO).

Formula: C₁₇H₁₈F₃N₅O₂

Purezza: 98%

Colore e forma: Solid

Peso molecolare: 381.35

Ref: TM-T11626