CAS 21462-39-5

Cloridrato di clindamicina

Descrizione:

Cloridrato di clindamicina è un antibiotico appartenente alla classe delle lincosamidi, utilizzato principalmente per trattare varie infezioni batteriche, in particolare quelle causate da batteri anaerobi e alcuni protozoi. È efficace contro le infezioni della pelle, le infezioni delle vie respiratorie e alcuni tipi di infezioni ossee. La sostanza appare come una polvere cristallina bianca o bianco sporco, solubile in acqua e metanolo, ma ha una solubilità limitata nei solventi organici. La sua formula chimica è C18H20ClN2O2S e ha un peso molecolare di circa 343,88 g/mol. Cloridrato di clindamicina agisce inibendo la sintesi proteica batterica, impedendo così la crescita e la riproduzione dei batteri. Viene spesso somministrato per via orale o endovenosa, a seconda della gravità dell'infezione. Gli effetti collaterali possono includere disturbi gastrointestinali, come diarrea, e in rari casi, può portare a diarrea associata a Clostridium difficile. A causa del suo meccanismo d'azione e dello spettro di attività, la clindamicina è un'opzione preziosa nel trattamento delle infezioni in cui la penicillina è inefficace o controindicata.

Formula: C₁₈H₃₄Cl₂N₂O₅S

InChI: InChI=1/C18H33ClN2O5S.ClH/c1-5-6-10-7-11(21(3)8-10)17(25)20-12(9(2)19)16-14(23)13(22)15(24)18(26-16)27-4;/h9-16,18,22-24H,5-8H2,1-4H3,(H,20,25);1H/t9?,10-,11+,12?,13+,14-,15-,16-,18-;/m0./s1

InChI key: InChIKey=AUODDLQVRAJAJM-XJQDNNTCSA-N

SMILES: [C@@H](NC(=O)[C@@H]1C[C@@H](CCC)CN1C)([C@H](C)Cl)[C@]2(O[C@H](SC)[C@H](O)[C@@H](O)[C@H]2O)[H].Cl

Sinonimi:

• (2R,4S)-N-[2-chloro-1-[(2S,3S,4R,5S,6S)-3,4,5-trihydroxy-6-methylsulfanyl-tetrahydropyran-2-yl]propyl]-1-methyl-4-propyl-pyrrolidine-2-carboxamide hydrochloride
• 7(S)-Chloro-7-deoxylincomycin hydrochloride
• 7-Chloro-7-deoxylincomycin hydrochloride
• <span class="text-smallcaps">L</smallcap>-threo-α-<smallcap>D</smallcap>-galacto-Octopyranoside, methyl 7-chloro-6,7,8-trideoxy-6-(1-methyl-4-propyl-<smallcap>L</span>-2-pyrrolidinecarboxamido)-1-thio-, monohydrochloride, trans- α-
• <span class="text-smallcaps">L</smallcap>-threo-α-<smallcap>D</span>-galacto-Octopyranoside, methyl 7-chloro-6,7,8-trideoxy-6-[[(1-methyl-4-propyl-2-pyrrolidinyl)carbonyl]amino]-1-thio-, monohydrochloride, (2S-trans)-
• <span class="text-smallcaps">L</smallcap>-threo-α-<smallcap>D</span>-galacto-Octopyranoside, methyl 7-chloro-6,7,8-trideoxy-6-[[[(2S,4R)-1-methyl-4-propyl-2-pyrrolidinyl]carbonyl]amino]-1-thio-, hydrochloride (1:1)
• <span class="text-smallcaps">L</smallcap>-threo-α-<smallcap>D</span>-galacto-Octopyranoside, methyl 7-chloro-6,7,8-trideoxy-6-[[[(2S,4R)-1-methyl-4-propyl-2-pyrrolidinyl]carbonyl]amino]-1-thio-, monohydrochloride
• Antirobe vet.
• Cleocin hydrochloride
• ClidamycinHydrochloride
• Clinacin
• Clindamycin HCl
• Clindavet
• Clindimycin hydrochloride
• Clindomycin hydrochloride
• Dalacina
• methyl 7-chloro-6,7,8-trideoxy-6-({[(2R)-1-methyl-4-propylpyrrolidinium-2-yl]carbonyl}amino)-1-thio-beta-L-erythro-octopyranoside chloride
• methyl 7-chloro-6,7,8-trideoxy-6-{[(4R)-1-methyl-4-propyl-L-prolyl]amino}-1-thio-L-threo-alpha-D-galacto-octopyranoside hydrochloride (1:1)
• L-threo-α-D-galacto-Octopyranoside, methyl 7-chloro-6,7,8-trideoxy-6-[[(1-methyl-4-propyl-2-pyrrolidinyl)carbonyl]amino]-1-thio-, monohydrochloride, (2S-trans)-
• Clindamycin hydrochloride
• L-threo-α-D-galacto-Octopyranoside, methyl 7-chloro-6,7,8-trideoxy-6-[[[(2S,4R)-1-methyl-4-propyl-2-pyrrolidinyl]carbonyl]amino]-1-thio-, hydrochloride (1:1)
• L-threo-α-D-galacto-Octopyranoside, methyl 7-chloro-6,7,8-trideoxy-6-[[[(2S,4R)-1-methyl-4-propyl-2-pyrrolidinyl]carbonyl]amino]-1-thio-, monohydrochloride
• L-threo-α-D-galacto-Octopyranoside, methyl 7-chloro-6,7,8-trideoxy-6-(1-methyl-4-propyl-L-2-pyrrolidinecarboxamido)-1-thio-, monohydrochloride, trans- α-
• (7S)-7-CHLORO-7-DEOXYLINCOMYCIN HYDROCHLORIDE
• clindomycinhydrochloride
• Lujiemycin
• CLINDAMYCINHYDROCHLORIDE,CRYSTAL
• L-threo-.alpha.-D-galacto-Octopyranoside, methyl 7-chloro-6,7,8-trideoxy-6-(2S,4R)-1-methyl-4-propyl-2-pyrrolidinylcarbonylamino-1-thio-, monohydrochloride
• clindimycinhydrochloride
• Clindaymcin Hydrochloride BP98,USP25,EP97
• 7(S)-CHLORO-7-DEOXYLINCOMYCIN HCL
• 7-chloro-7-deoxylincomycinhydrochloride
• monohydrochloride,(2s-methyl-4-propyl-2-pyrrolidinyl)carbonyl]amino]-1-thio
• CLEOCIN
• (2S-TRANS)-METHYL 7-CHLORO-6,7,8-TRIDEOXY-6[[(1-METHYL-4-PROPYL-2-PYRROLIDINYL)CARBONYL]AMINO]-1-THIO-L-THREO-ALPHA-D-GALACTO-OCTOPYRANOSIDE
• 7(S)-CHLORO-7-DEOXYLINCOMYCIN
• CLINDAMYCIN HC

Clindamycin Hydrochloride Monohydrate

CAS: 18323-44-9, 21462-39-5, 58207-19-5

Formula: C₁₈H₃₃ClN₂O₅S·HCl·H₂O

Purezza: >98.0%(T)(HPLC)

Colore e forma: White to Almost white powder to crystal

Peso molecolare: 479.46

Ref: 3B-C2256

Clindamycin Hydrochloride

CAS: 21462-39-5

Colore e forma: Neat

Ref: 61-FOR0259.00

CLINDAMYCIN HYDROCHLORIDE RS

CAS: 21462-39-5

CLINDAMYCIN HYDROCHLORIDE RS

Ref: 41-ICRS46473

CLINDAMYCIN HYDROCHLORIDE CRS

CAS: 21462-39-5

CLINDAMYCIN HYDROCHLORIDE CRS

Formula: C₁₈H₃₄Cl₂N₂O₅S

Colore e forma: Added Modified

Peso molecolare: 461.444

Ref: 41-C2250000

(7S)-7-Chloro-7-deoxylincomycin hydrochloride

CAS: 21462-39-5

Formula: C₁₈H₃₄Cl₂N₂O₅S

Purezza: 95%

Colore e forma: Solid

Peso molecolare: 461.4440

Ref: IN-DA003P0L

Clindamycin HCl (Clindamycin Phosphate EP Impurity E HCl)

CAS: 21462-39-5

Formula: C₁₈H₃₃ClN₂O₅S·HCl

Colore e forma: White To Off-White Solid

Peso molecolare: 424.99 36.46

Ref: 4Z-C-5071

Clindamycin hydrochloride

CAS: 21462-39-5

Formula: C₁₈H₃₃ClN₂O₅S·HCl·xH₂O

Purezza: ≥ 800μg/mg (C18H33ClN2O5S, as is)

Colore e forma: White to off-white powder

Peso molecolare: 461.44 (anhydrous)

Ref: 7W-GA5034

Clindamycin hydrochloride

CAS: 21462-39-5

Clindamycin hydrochloride

Purezza: ≥98%

Peso molecolare: 461.44g/mol

Ref: 54-BUP14814

Clindamycin hydrochloride

CAS: 21462-39-5

Clindamycin hydrochloride

Formula: C₁₈H₃₃ClN₂O₅S·ClH

Purezza: 94% (q-nmr) (calculated (Typical Value in Batch COA)

Colore e forma: white powder

Peso molecolare: 461.44395g/mol

Ref: 54-BIC0117

Clindamycin Hydrochloride

CAS: 21462-39-5

Colore e forma: Neat

Ref: 86-MM0259.00

Clindamycin 1000 µg/mL in Acetonitrile

Prodotto controllato

CAS: 21462-39-5

Formula: C₁₈H₃₃ClN₂O₅S·ClH

Colore e forma: Single Solution

Peso molecolare: 461.44

Ref: 04-A11670090AL-1000

Clindamycin hydrochloride

Prodotto controllato

CAS: 21462-39-5

Formula: C₁₈H₃₃ClN₂O₅S·ClH

Colore e forma: Neat

Peso molecolare: 461.44

Ref: 04-C11670100

Clindamycin hydrochloride

CAS: 21462-39-5

Clindamycin hydrochloride (Clinimycin HCl) inhibits protein synthesis by acting on the 50S ribosomal. Clindamycin is a chlorinated broad-spectrum antibiotic.

Formula: C₁₈H₃₃ClN₂O₅S·HCl

Purezza: 99.80%

Colore e forma: White Crystalline Powder

Peso molecolare: 461.44

Ref: TM-T6448

Clindamycin Hydrochloride

CAS: 21462-39-5

Formula: C₁₈H₃₃ClN₂O₅SHCl

Peso molecolare: 425.0 : 36.5

Ref: ST-EA-CP-C26021

Clindamycin Hydrochloride

CAS: 21462-39-5

Impurity Clindamycin Phosphate EP Impurity E
Stability Hygroscopic
Applications Clindamycin Hydrochloride (Clindamycin Phosphate EP Impurity E) is a semi-synthetic antibiotic prepared from Lincomycin. Antibacterial.
References Birkenmeyer, R.D., et al.: J. Med. Chem., 13, 616 (1970); Oesterling, et al.: J. Pharm. Sci., 59, 63 (1970); Gray, J.E., et al.: Toxicol. Appl. Pharmacol., 21, 516 (1972); Brown, L.W., et al.: Anal. Profiles Drug Subs., 10, 75 (1981);

Formula: C₁₈H₃₃ClN₂O₅S·ClH

Colore e forma: White To Off-White

Peso molecolare: 461.44

Ref: TR-C580000

Clindamycin hydrochloride

CAS: 21462-39-5

Inhibitor of protein synthesis; lincosamide class

Formula: C₁₈H₃₄Cl₂N₂O₅S

Colore e forma: White Powder

Peso molecolare: 461.44 g/mol

Ref: 3D-AC07735

Clindamycin hydrochloride - 94%

CAS: 21462-39-5

Clindamycin hydrochloride - 94% is an antibiotic that belongs to the lincosamide class of antibiotics, derived from the bacterium Streptomyces lincolnensis. This compound functions predominantly as a bacterial protein synthesis inhibitor, exerting its effects by binding to the 50S subunit of the bacterial ribosome. This binding action disrupts the process of peptide chain elongation, thereby impeding the growth and proliferation of susceptible bacteria.

Formula: C₁₈H₃₃ClN₂O₅S·HCl

Colore e forma: Powder

Peso molecolare: 461.44 g/mol

Ref: 3D-AC178993

Clindamycin (hydrochloride)

CAS: 21462-39-5

Purezza: 98%

Peso molecolare: 460.16

Ref: 10-F554440

Cis-Clindamycin Hydrochloride

Prodotto controllato

CAS: 21462-39-5

Formula: C₁₈H₃₃ClN₂O₅S·ClH

Colore e forma: Neat

Peso molecolare: 460.15655

Ref: TR-C580080