CAS 2182-14-1

(-)-Vindolina

Descrizione:

(-)-Vindolina è un alcaloide che si trova naturalmente, estratto principalmente dalla pianta Catharanthus roseus, comunemente nota come pervinca del Madagascar. È caratterizzato dalla sua struttura complessa, che include un telaio tetraciclico e vari gruppi funzionali, contribuendo alla sua attività biologica. Questo composto è noto per il suo ruolo nella biosintesi del farmaco antitumorale vincristina, rendendolo significativo nella chimica medicinale. (-)-Vindolina presenta un centro chirale, risultando nella sua specifica attività ottica, che è cruciale per le sue proprietà farmacologiche. La sostanza è tipicamente un solido cristallino bianco a bianco sporco ed è solubile in solventi organici come metanolo ed etanolo, ma meno solubile in acqua. La sua formula molecolare riflette un grado relativamente alto di complessità ed è spesso studiata per i suoi potenziali effetti terapeutici, in particolare in oncologia. Inoltre, le interazioni di (-)-Vindolina con i meccanismi cellulari e la sua capacità di inibire la divisione cellulare lo rendono un argomento di interesse nella ricerca sul cancro e nello sviluppo di farmaci.

Formula: C₂₅H₃₂N₂O₆

InChI: InChI=1S/C25H32N2O6/c1-6-23-10-7-12-27-13-11-24(19(23)27)17-9-8-16(31-4)14-18(17)26(3)20(24)25(30,22(29)32-5)21(23)33-15(2)28/h7-10,14,19-21,30H,6,11-13H2,1-5H3/t19-,20+,21+,23+,24+,25-/m0/s1

InChI key: InChIKey=CXBGOBGJHGGWIE-ACSXSLCXSA-N

SMILES: C(C)[C@@]12[C@]3([C@@]4([C@]([C@](C(OC)=O)(O)[C@@H]1OC(C)=O)(N(C)C=5C4=CC=C(OC)C5)[H])CCN3CC=C2)[H]

Sinonimi:

• (2beta,3beta,4beta,5alpha,12beta,19alpha)-4-(Acetyloxy)-6,7-didehydro-3-hydroxy-16-methoxy-1-methyl-aspidospermidine-3-carboxylic acid methyl ester
• 1H-Indolizino[8,1-cd]carbazole, aspidospermidine-3-carboxylic acid deriv.
• Aspidospermidine-3-Carboxylicacid,4-(Acetyloxy)-6,7-Didehydro-3-Hydroxy-16-Me
• Aspidospermidine-3-carboxylic acid, 4-(acetyloxy)-6,7-didehydro-3-hydroxy-16-methoxy-1-methyl-, methyl ester, (2beta,3beta,4beta,5alpha,12beta,19alpha)-
• Aspidospermidine-3-carboxylic acid, 4-(acetyloxy)-6,7-didehydro-3-hydroxy-16-methoxy-1-methyl-, methyl ester, (2β,3β,4β,5α,12R,19α)-
• Aspidospermidine-3-carboxylic acid, 4-(acetyloxy)-6,7-didehydro-3-hydroxy-16-methoxy-1-methyl-, methyl ester, (2β,3β,4β,5α,12β,19α)-
• Bufexamacum
• Methyl (2Beta,3Beta,4Beta,5Alpha,12Beta,19Alpha)-4-(Acetyloxy)-3-Hydroxy-16-Methoxy-1-Methyl-6,7-Didehydroaspidospermidine-3-Carboxylate
• Methyl (2Beta,3Beta,4Beta,5Alpha,19Alpha)-4-(Acetyloxy)-3-Hydroxy-16-Methoxy-1-Methyl-6,7-Didehydroaspidospermidine-3-Carboxylate
• Methyl (2Beta,3Beta,4Beta,5Xi,12Beta,19Alpha)-4-(Acetyloxy)-3-Hydroxy-16-Methoxy-1-Methyl-6,7-Didehydroaspidospermidine-3-Carboxylate
• Methyl (2Beta,4Beta,5Alpha,12Beta,19Alpha)-4-(Acetyloxy)-3-Hydroxy-16-Methoxy-1-Methyl-6,7-Didehydroaspidospermidine-3-Carboxylate
• NSC 91994
• Thoxy-1-Methyl-,Methylester,(2-Beta,3-Beta,4-Beta,5-Alpha,12-Beta,19-Alpha)
• Vindolin
• Vindoline Tartrate
• Vindoline free base
• Vindoline, (-)-

Aspidospermidine-3-carboxylic acid,4-(acetyloxy)-6,7-didehydro-3-hydroxy-16-methoxy-1-methyl-, methylester, (2b,3b,4b,5a,12R,19a)-

CAS: 2182-14-1

Formula: C₂₅H₃₂N₂O₆

Purezza: 95%

Colore e forma: Solid

Peso molecolare: 456.5314

Ref: IN-DA00I48E

Vindoline

CAS: 2182-14-1

Vindoline is an indole alkaloid that exhibits antimitotic activity by inhibiting microtubule assembly.

Formula: C₂₅H₃₂N₂O₆

Purezza: 99.89%

Colore e forma: White Or Offwhite Powder

Peso molecolare: 456.53

Ref: TM-T2773

Vindoline

CAS: 2182-14-1

Formula: C₂₅H₃₂N₂O₆

Peso molecolare: 456.54

Ref: 4Z-V-116001

Vindoline

CAS: 2182-14-1

Vindoline

Purezza: ≥98%

Peso molecolare: 456.53g/mol

Ref: 54-BUP06409

Vindoline

CAS: 2182-14-1

Vindoline

Purezza: 98%

Peso molecolare: 456.53g/mol

Ref: 54-OR1025615

Vindoline

CAS: 2182-14-1

Formula: C₂₅H₃₂N₂O₆

Purezza: >98.0%(HPLC)(qNMR)

Colore e forma: White to Light yellow powder to crystal

Peso molecolare: 456.54

Ref: 3B-V0193

Vindoline

CAS: 2182-14-1

Formula: C₂₅H₃₂N₂O₆

Purezza: 95%~99%

Peso molecolare: 456.539

Ref: BP-BP1443

Vindoline

CAS: 2182-14-1

Colore e forma: Neat

Ref: 86-MM3359.01

Vindoline

CAS: 2182-14-1

Formula: C₂₅H₃₂N₂O₆

Purezza: (HPLC) ≥ 98.0%

Colore e forma: White powder

Peso molecolare: 456.53

Ref: 7W-GP8222

Vindoline

Prodotto controllato

CAS: 2182-14-1

Formula: C₂₅H₃₂N₂O₆

Colore e forma: Neat

Peso molecolare: 456.53

Ref: TR-V416500

Vindoline

Prodotto controllato

CAS: 2182-14-1

Vindoline is a monoterpenoid indole alkaloid that is found in plants of the genus Vinca. It has been used to prepare samples for thin-layer chromatography, and can be detected by sephadex g-100. The reaction mechanism of vindoline is thought to be similar to other indole alkaloids, such as tryptamine, where two molecules are combined through a covalent bond between the amine group and the carbonyl group. Vindoline has been shown to inhibit polymerase chain reactions and also has a number of biological properties that could be useful in tissue culture. This natural product structure has been shown to have steric interactions with enzymes, including tyrosinase, which is involved in plant metabolism. Vindoline may also be able to inhibit plant physiology by altering photosynthesis or respiration.

Formula: C₂₅H₃₂N₂O₆

Purezza: Min. 98 Area-%

Colore e forma: White Powder

Peso molecolare: 456.53 g/mol

Ref: 3D-FV10830

Vindoline

CAS: 2182-14-1

Formula: C₂₅H₃₂N₂O₆

Peso molecolare: 456.54

Ref: ST-EA-CP-V49003

Vindoline

CAS: 2182-14-1

Formula: C₂₅H₃₂N₂O₆

Colore e forma: White To Off-White Solid

Peso molecolare: 456.54

Ref: 4Z-V-040012