CAS 21967-41-9

Baicalina

Descrizione:

Baicalina è un glicoside flavonoide derivato dalle radici di Scutellaria baicalensis, una pianta comunemente usata nella medicina tradizionale cinese. La sua struttura chimica consiste in uno scheletro di flavone con un gruppo di acido glucuronico, che contribuisce alla sua solubilità e bioattività. Baicalina è noto per le sue varie proprietà farmacologiche, inclusi effetti antinfiammatori, antiossidanti e neuroprotettivi. È stato studiato per le sue potenziali applicazioni terapeutiche in condizioni come ansia, depressione e malattie neurodegenerative. Il composto presenta un profilo di tossicità relativamente basso, rendendolo un candidato per ulteriori ricerche in chimica medicinale. Baicalina è tipicamente caratterizzato dal suo colore giallastro ed è solubile in acqua e alcol, ma meno in solventi non polari. Il suo meccanismo d'azione coinvolge la modulazione di varie vie di segnalazione, comprese quelle relative allo stress ossidativo e all'infiammazione. In generale, Baicalina rappresenta un'area di interesse significativa sia nella chimica dei prodotti naturali che nella farmacologia grazie alle sue diverse attività biologiche e potenziali benefici per la salute.

Formula: C₂₁H₁₈O₁₁

InChI: InChI=1/C21H18O11/c22-9-6-10(8-4-2-1-3-5-8)30-11-7-12(14(23)15(24)13(9)11)31-21-18(27)16(25)17(26)19(32-21)20(28)29/h1-7,16-19,21,23-27H,(H,28,29)

InChI key: InChIKey=IKIIZLYTISPENI-ZFORQUDYSA-N

SMILES: OC1=C2C(OC(=CC2=O)C3=CC=CC=C3)=CC(O[C@@H]4O[C@H](C(O)=O)[C@@H](O)[C@H](O)[C@H]4O)=C1O

Sinonimi:

• 5,6-Dihydroxy-4-oxo-2-phenyl-4H-1-benzopyran-7-yl β-<span class="text-smallcaps">D</span>-glucopyranosiduronic acid
• 5,6-Dihydroxy-4-oxygen-2-phenyl-4H-1-benzopyran-7-beta-D-glucopyranose acid
• 5,6-dihydroxy-4-oxo-2-phenyl-4H-chromen-7-yl beta-D-glucopyranosiduronic acid
• 5,6-dihydroxy-4-oxo-2-phenyl-4H-chromen-7-yl hexopyranosiduronic acid
• Baicalein 7-O-glucuronide
• Baicalein 7-O-β-<span class="text-smallcaps">D</span>-glucuronide
• Baicalein 7-glucuronide
• β-<span class="text-smallcaps">D</span>-Glucopyranosiduronic acid, 5,6-dihydroxy-4-oxo-2-phenyl-4H-1-benzopyran-7-yl
• Baicalin
• 5,6-Dihydroxy-4-oxo-2-phenyl-4H-1-benzopyran-7-yl β-D-glucopyranosiduronic acid
• β-D-Glucopyranosiduronic acid, 5,6-dihydroxy-4-oxo-2-phenyl-4H-1-benzopyran-7-yl
• Baicalein 7-O-β-D-glucuronide
• BAICALIN 7-B-D-GLUCOPYRANOSIDURONATE HYDRATE
• BAICALIN(P)
• BAICALIN 7-BETA-D-GLUCOPYRANOSIDURONATE HYDRATE
• Bassora
• Baicalin Injection
• BAICALIN HYDRATE
• Baicailin
• Radix
• BAICALIN, 98+% BY HPLC
• BAICALEIN 7-BETA-D-GLUCOPYRANOSIDURONATE HYDRATE
• ASTRAGALIN(KAEMPFEROL-3-O-GLUCOSIDE)(P)
• BAICALINB-D-GLUCOPYRANOSIDURONIC ACID, 5,6-DIHYDROXY-4-OXO-2-PHENYL-4H-1-BENZOPYRAN-7-YL,
• BAICALIN hplc
• 7-GLUCURONICACID-5,6-DIHYDROXYFLAVONE
• BAICALIN WITH HPLC
• 5,6-Dihydroxyflavon-7-yl β-D-glucopyranosiduronic acid

Baicalin

CAS: 21967-41-9

Formula: C₂₁H₁₈O₁₁

Purezza: >90.0%(T)

Colore e forma: White to Yellow powder to crystal

Peso molecolare: 446.36

Ref: 3B-B2835

Baicalin

CAS: 21967-41-9

Baicalin analytical standard provided with w/w absolute assay, to be used for quantitative titration.

Formula: C₂₁H₁₈O₁₁

Purezza: (HPLC) ≥99%

Colore e forma: Powder

Peso molecolare: 446.36

Ref: 11-1280S

BAICALIN CRS

CAS: 21967-41-9

BAICALIN CRS

Formula: C₂₁H₁₈O₁₁

Colore e forma: Powder.

Peso molecolare: 446.361

Ref: 41-Y0001273

Baicalein 7-O-Glucuronide

CAS: 21967-41-9

Other glycosides, natural or reproduced by synthesis, and their salts, ethers, esters and other derivatives

Formula: C₂₁H₁₈O₁₁

Colore e forma: Yellow Powder

Peso molecolare: 446.08491

Ref: 45-1048368

Baicalin

CAS: 21967-41-9

Baicalin (Baicalein 7-O-β-D-glucuronide) is a prolyl endopeptidase inhibitor isolated from scutellaria baicalensis, with antioxidant, anti-tumor, anti-HIV

Formula: C₂₁H₁₈O₁₁

Purezza: 90.08% - 99.32%

Colore e forma: Yellow Powder

Peso molecolare: 446.36

Ref: TM-T2775

(2S,3S,4S,5R,6S)-6-[(5,6-dihydroxy-4-oxo-2-phenyl-4H-chromen-7-yl)oxy]-3,4,5-trihydroxyoxane-2-carboxylic acid

CAS: 21967-41-9

Formula: C₂₁H₁₈O₁₁

Purezza: 90%

Colore e forma: Solid

Peso molecolare: 446.3610

Ref: IN-DA00I49P

Baicalin 7-b-D-glucuronide

CAS: 21967-41-9

Formula: C₂₁H₁₈O₁₁

Purezza: ≥ 95.0%

Colore e forma: White, off-white or yellow powder

Peso molecolare: 446.36

Ref: 7W-GC0614

Baicalin

CAS: 21967-41-9

Baicalin

Purezza: 90%

Peso molecolare: 446.36g/mol

Ref: 54-OR1028641

Baicalin

CAS: 21967-41-9

Baicalin

Purezza: ≥90%

Peso molecolare: 446.36g/mol

Ref: 54-BUP14961

Baicalin

CAS: 21967-41-9

Baicalin is a flavonoid and a major component of a herbal medicine, Sho-saiko-to, which is commonly used for treatment of chronic hepatitis in Japan and China. baicalin acts as anti-oxidants, also causes cytotoxic effect,and induces caspase-3 activation and apoptosis via mitochondrial pathway.

Formula: C₂₁H₁₈O₁₁

Purezza: 95%~99%

Colore e forma: Yellow powder

Peso molecolare: 446.364

Ref: BP-BP0233

Baicalin

CAS: 21967-41-9

Formula: C₂₁H₁₈O₁₁

Colore e forma: Neat

Peso molecolare: 446.36

Ref: 04-C10418100

Baicalin RS

CAS: 21967-41-9

Colore e forma: Pale Yellow To Yellow

Ref: 2K-1111000021

Baicalin

CAS: 21967-41-9

Natural glycoside

Formula: C₂₁H₁₈O₁₁

Purezza: ≥ 90.0 % (HPLC)

Colore e forma: Powder

Peso molecolare: 446.37

Ref: 5G-89322

Baicalin

Prodotto controllato

CAS: 21967-41-9

Stability Hygroscopic
Applications Baicalin, Baicalin is the glucuronide of Baicalein (B115250). Baicalin is a known prolyl endopeptidase inhibitor, induces apoptosis in pancreatic cancer cells,[3] and affects the GABA receptors.
References Tarrago, T., et al.: Bioorg. Med. Chem, 16 (15), 7516 (2008); Takahashi, H., et al.: Biochim Biophys Acta, 1813 (8), 1465 (2011);

Formula: C₂₁H₁₈O₁₁

Colore e forma: Neat

Peso molecolare: 446.36

Ref: TR-B115255

5,6-Dihydroxy-4-oxo-2-phenyl-4H-1-benzopyran-7-yl ?-D-Glucopyranosiduronic Acid

CAS: 21967-41-9

Formula: C₂₁H₁₈O₁₁

Purezza: 98.0%

Peso molecolare: 446.364

Ref: 10-F547433

(2S,3S,4S,5R,6S)-6-[(4,6-dihydroxy-5-oxo-2-phenyl-5H-chromen-7-yl)oxy]-3,4,5-trihydroxyoxane-2-carboxylic acid

CAS: 21967-41-9

Purezza: 95%

Peso molecolare: 446.3640137

Ref: 10-F808019

Baicalin 7-b-D-glucuronide

CAS: 21967-41-9

Baicalin 7-b-D-glucuronide is a flavonoid metabolite, which is primarily derived from the root of the plant *Scutellaria baicalensis*, commonly known as Chinese skullcap. This compound occurs as part of the extensive array of flavonoids in traditional medicinal plants used in various ethnic medicine systems.

Formula: C₂₁H₁₈O₁₁

Purezza: Min. 95 Area-%

Colore e forma: White Powder

Peso molecolare: 446.36 g/mol

Ref: 3D-MB08110