CAS 220119-17-5

Selamectina

Descrizione:

Selamectina è un derivato semisintetico dell'avermentina, utilizzato principalmente come agente antiparassitario in medicina veterinaria. È efficace contro una varietà di parassiti esterni e interni, tra cui pulci, zecche e alcuni tipi di vermi in cani e gatti. Selamectina funziona legandosi ai canali del cloruro attivati dal glutammato nel sistema nervoso dei parassiti, portando a paralisi e morte. La sostanza viene tipicamente somministrata topicamente, consentendo un rilascio sostenuto e un'efficacia prolungata. Selamectina è caratterizzato dalla sua alta lipofilia, che aiuta nella sua assorbimento attraverso la pelle e distribuzione nel corpo. Ha un profilo di tossicità relativamente basso nei mammiferi, rendendolo sicuro per l'uso negli animali domestici quando applicato come indicato. Inoltre, Selamectina è stabile in condizioni normali di stoccaggio e ha una lunga durata, contribuendo alla sua praticità come trattamento veterinario. La sua efficacia e il profilo di sicurezza lo hanno reso una scelta popolare per la gestione delle infezioni parassitarie negli animali da compagnia.

Formula: C₄₃H₆₃NO₁₁

InChI: InChI=1S/C43H63NO11/c1-24-11-10-14-30-23-50-40-36(44-48)27(4)19-33(43(30,40)47)41(46)52-32-20-31(16-15-25(2)38(24)53-35-21-34(49-6)37(45)28(5)51-35)54-42(22-32)18-17-26(3)39(55-42)29-12-8-7-9-13-29/h10-11,14-15,19,24,26,28-29,31-35,37-40,45,47-48H,7-9,12-13,16-18,20-23H2,1-6H3/b11-10+,25-15+,30-14+,44-36-/t24-,26-,28-,31+,32-,33-,34-,35-,37-,38-,39-,40+,42+,43+/m0/s1

InChI key: InChIKey=AFJYYKSVHJGXSN-XHKIUTQPSA-N

SMILES: O[C@@]1/2[C@]3(/C(=N\O)/C(C)=C[C@]1(C(=O)O[C@@]4(C[C@@]5(O[C@@]([C@@H](C)CC5)(C6CCCCC6)[H])O[C@@](C4)(C/C=C(\C)/[C@@H](O[C@H]7C[C@H](OC)[C@@H](O)[C@H](C)O7)[C@@H](C)\C=C\C=C2/CO3)[H])[H])[H])[H]

Sinonimi:

• (2aE,4E,5'S,6S,6'S,7S,8E,11R,13R,15S,17aR,20Z,20aR,20bS)-6'-cyclohexyl-20b-hydroxy-20-(hydroxyimino)-5',6,8,19-tetramethyl-17-oxo-3',4',5',6,6',10,11,14,15,17,17a,20,20a,20b-tetradecahydro-2H,7H-spiro[11,15-methanofuro[4,3,2-pq][2,6]benzodioxacyclooctadecine-13,2'-pyran]-7-yl (4ξ)-2,6-dideoxy-3-O-methyl-L-threo-hexopyranoside
• (2aE,4E,5'S,6S,6'S,7S,8E,11R,13R,15S,17aR,20aR,20bS)-6'-cyclohexyl-7-((2,6-dideoxy-3-O-methyl-alpha-L-arabino-hexopyranosyl)oxy)-3',4',5',6,6',7,10,11,14,15,20a,20b-dodecahydro-20b-hydroxy-5',6,8,19-tetramethylspiro(11,15-methano-2H,13H,17H-furo(4,3,2-pq)(2,6)benzodioxacyclooctadecin-13,2'-(2H)pyran)-17,20(17aH)-dione 20-oxime
• (5'S,6S,6'S,7S,11R,13R,15S,17aR,20Z,20aR,20bS)-6'-cyclohexyl-20b-hydroxy-20-(hydroxyimino)-5',6,8,19-tetramethyl-17-oxo-3',4',5',6,6',10,11,14,15,17,17a,20,20a,20b-tetradecahydro-2H,7H-spiro[11,15-methanofuro[4,3,2-pq][2,6]benzodioxacyclooctadecine-13,2'-pyran]-7-yl 2,6-dideoxy-3-O-methyl-α-L-arabino-hexopyranoside
• (5Z)-25-Cyclohexyl-4′-O-de(2,6-dideoxy-3-O-methyl-α-<span class="text-smallcaps">L</span>-arabino-hexopyranosyl)-5-demethoxy-25-de(1-methylpropyl)-22,23-dihydro-5-(hydroxyimino)avermectin A_1a
• 25-Cyclohexyl-4'-O-de(2,6-dideoxy-3-O-methyl-alpha-L-arabino-hexopyranosyl)-5-demethoxy-25-de(1-methylpropyl)-22,23-dihydro-5-(hydroxyimino)-avermectin A1a
• 25-cyclohexyl-25-de(1-methylpropyl)-5-deoxy-22 23-dihydro-5-(hydroxyimino)-avermectin B1 monosaccharide
• Avermectin A1a, 25-cyclohexyl-4'-O-de(2,6-dideoxy-3-O-methyl-a-L-arabino-hexopyranosyl)-5-demethoxy-25-de(1-methylpropyl)-22,23-dihydro-5-(hydroxyimino)-
• Avermectin A1a,25-cyclohexyl-4'-O-de(2,6-dideoxy-3-O-methyl-a-L-arabino-hexopyranosyl)-5-demethoxy-25-de(1-methylpropyl)-22,23-dihydro-5-(hydroxyimino)-,(5Z)-
• Avermectin A_1a, 25-cyclohexyl-4′-O-de(2,6-dideoxy-3-O-methyl-α-<span class="text-smallcaps">L</span>-arabino-hexopyranosyl)-5-demethoxy-25-de(1-methylpropyl)-22,23-dihydro-5-(hydroxyimino)-, (5Z)-
• Chanhold
• Evicto
• Revolution
• Revolution (antibiotic)
• Selamectin
• Selamectin [USAN:INN]
• Selarid
• Stronghold
• Uk-124,114
• Unii-A2669Owx9N

Selamectin

CAS: 220119-17-5

Formula: C₄₃H₆₃NO₁₁

Purezza: >95.0%(HPLC)

Colore e forma: White to Light yellow powder to crystal

Peso molecolare: 769.97

Ref: 3B-E1500

SELAMECTIN FOR PEAK IDENTIFICATION CRS

CAS: 220119-17-5

SELAMECTIN FOR PEAK IDENTIFICATION CRS

Formula: C₄₃H₆₃NO₁₁

Colore e forma: Powder.

Peso molecolare: 769.9604

Ref: 41-Y0001734

Selamectin

CAS: 220119-17-5

Lactones, nesoi

Formula: C₄₃H₆₃NO₁₁

Colore e forma: White Off-White Crystalline Powder

Peso molecolare: 769.44011

Ref: 45-1611729

Selamectin

CAS: 220119-17-5

Formula: C₄₃H₆₃NO₁₁

Purezza: 95%

Colore e forma: Solid

Peso molecolare: 769.9604

Ref: IN-DA00BBNQ

Selamectin

CAS: 220119-17-5

Selamectin

Purezza: ≥98%

Peso molecolare: 769.96g/mol

Ref: 54-BUP15413

Selamectin

CAS: 220119-17-5

Selamectin

Purezza: 95%

Peso molecolare: 769.96g/mol

Ref: 54-OR1025007

Selamectin

CAS: 220119-17-5

Formula: C₄₃H₆₃NO₁₁

Colore e forma: White To Off-White Solid

Peso molecolare: 769.98

Ref: 4Z-S-064001

Selamectin 100 µg/mL in Acetonitrile

CAS: 220119-17-5

Formula: C₄₃H₆₃NO₁₁

Colore e forma: Single Solution

Peso molecolare: 769.96

Ref: 04-A16931500AL-100

Selamectin

Prodotto controllato

CAS: 220119-17-5

Formula: C₄₃H₆₃NO₁₁

Colore e forma: Neat

Peso molecolare: 769.96

Ref: 04-C16931500

Selamectin

CAS: 220119-17-5

Ref: 7W-GW6519

Selamectin

CAS: 220119-17-5

Selamectin (UK-124114) is a macrocyclic lactone derivative of ivermectin, an anthelmintic that potentiates glutamate- and GABA-gated chloride channel opening in

Formula: C₄₃H₆₃NO₁₁

Purezza: 99.84%

Colore e forma: Solid

Peso molecolare: 769.96

Ref: TM-T4059

Selamectin

CAS: 220119-17-5

Purezza: ≥97%

Peso molecolare: 769.9730225

Ref: 10-F951524

Selamectin

Prodotto controllato

CAS: 220119-17-5

Applications Selamectin is a topical parasiticide and also used as a veterinary antihelminithic agent on animals.
References Eshar, D., et al.: J. Am. Veterin. Med. Association., 241, 1056 (2012); Geis-Asteggiante, L., et al.: J. Chromatograph., 1258, 43 (2012);

Formula: C₄₃H₆₃NO₁₁

Colore e forma: Neat

Peso molecolare: 769.96

Ref: TR-S247990