CAS 22254-24-6

Bromuro di ipratropio

Descrizione:

Bromuro di ipratropio è un composto di ammonio quaternario sintetico utilizzato principalmente come broncodilatatore nel trattamento di condizioni respiratorie come asma e malattia polmonare ostruttiva cronica (BPCO). Funziona come un agente anticolinergico, inibendo l'azione dell'acetilcolina sui recettori muscarinici delle vie aeree, portando al rilassamento della muscolatura liscia bronchiale e a un miglioramento del flusso d'aria. La sostanza appare come una polvere cristallina bianca o bianco sporco ed è solubile in acqua, rendendola adatta per formulazioni per inalazione. La sua formula chimica è C20H30BrN2O3 e ha un peso molecolare di circa 392,37 g/mol. Bromuro di ipratropio viene tipicamente somministrato per inalazione, sia tramite inalatori a dose misurata che nebulizzatori, consentendo un'azione localizzata nei polmoni con effetti collaterali sistemici minimi. Gli effetti collaterali comuni possono includere secchezza delle fauci, tosse e irritazione della gola. A causa del suo meccanismo d'azione, è spesso usato in combinazione con beta-agonisti per migliorare l'efficacia terapeutica nella gestione del broncospasmo.

Formula: C₂₀H₂₉Br₂NO₃

InChI: InChI=1/C20H30NO3.BrH/c1-14(2)21(3)16-9-10-17(21)12-18(11-16)24-20(23)19(13-22)15-7-5-4-6-8-15;/h4-8,14,16-19,22H,9-13H2,1-3H3;1H/q+1;/p-1/t16-,17?,18-,19?,21?;/m1./s1

InChI key: InChIKey=LHLMOSXCXGLMMN-VVQPYUEFNA-M

SMILES: C(C)(C)[N@@+]1(C)[C@]2(C[C@H](OC(C(CO)C3=CC=CC=C3)=O)C[C@@]1(CC2)[H])[H].[Br-]

Sinonimi:

• (1R,5S)-3-[(3-hydroxy-2-phenylpropanoyl)oxy]-8-methyl-8-(propan-2-yl)-8-azoniabicyclo[3.2.1]octane bromide
• 1α<span class="text-smallcaps">H</smallcap>,5α<smallcap>H</span>-Tropanium, 3α-hydroxy-8-isopropyl-, bromide, (±)-tropate
• 3-[(3-Hydroxy-2-Phenylpropanoyl)Oxy]-8-Methyl-8-(Propan-2-Yl)-8-Azoniabicyclo[3.2.1]Octane Bromide
• 8-Azoniabicyclo[3.2.1]octane, 3-(3-hydroxy-1-oxo-2-phenylpropoxy)-8-methyl-8-(1-methylethyl)-, bromide (1:1), (3-endo,8-syn)-
• 8-Azoniabicyclo[3.2.1]octane, 3-(3-hydroxy-1-oxo-2-phenylpropoxy)-8-methyl-8-(1-methylethyl)-, bromide, (3-endo,8-syn)-
• 8-Azoniabicyclo[3.2.1]octane, 3-(3-hydroxy-1-oxo-2-phenylpropoxy)-8-methyl-8-(1-methylethyl)-, bromide, (endo,syn)-
• 8-Isopropylatropinium bromide
• Aerovent
• Atrovent
• Atrovent forte
• IpratropiumBromide
• Ipraxa
• N-Isopropylatropinium bromide
• N-Isopropylnoratropinium bromomethylate
• Sch 100
• Sch 1000
• [(1R)-8-isopropyl-8-methyl-8-azoniabicyclo[3.2.1]octan-3-yl] 3-hydroxy-2-phenyl-propanoate bromide
• 1αH,5αH-Tropanium, 3α-hydroxy-8-isopropyl-, bromide, (±)-tropate
• ipratropiumbromid
• (ENDO,SYN)-(+/-)-3-(3-HYDROXY-1-OXO-2-PHENYLPROPOXY)-8-METHYL-8-(1-METHYLETHYL)-8-AZONIABICYCLO[3.2.1]OCTANE BROMIDE
• pate
• (3-endo,8-syn)-3-(3-Hydroxy-1-oxo-2-phenylpropyl)-8-methyl-8-(1-methylethyl)-8-azoniabicyclo[3.2.1]octane Bromode Monohydrate
• IPRATROPIUM BROMIDE MONOHYDRATE
• 1-alpha-h,5-alpha-h-tropanium,3-alpha-hydroxy-8-isopropyl-,bromide,(+-)-trop
• atem
• Atropine Isopropyl Bromid
• 8-isopropylnoratropinemethobromide
• itrop
• IPRATROPIUM BROMIDE HYDRATE
• [(1r,5s)-8-methyl-8-propan-2-yl-8-azoniabicyclo[3.2.1]octan-3-yl] 3-hydroxy-2-phenylpropanoate bromide
• (1s,3s,5r)-3-tropyloxy-8-isopropyltropaniumbromide
• n-isopropylnoratropiniumbromomethylate
• ATROPINE ISOPROPYLBROMIDE
• 3-alpha-hydroxy-8-isopropyl-1-alpha-h,5-alpha-h-tropaniumbromide(+-)-tropat
• 3-(3-HYDROXY-1-OXO-2-PHENYLPROPOXY)-8-METHYL-8-(1-METHYLETHYL)-8-AZONIABICYCLO[3.2.1]-OCTANE BROMIDE
• sch1000

Ipratropium bromide, 98%

CAS: 22254-24-6

Muscarinic acetylcholine receptor antagonist and a bronchodilator

Formula: C₂₀H₃₀BrNO₃

Purezza: 98%

Colore e forma: White to cream, Powder

Peso molecolare: 412.37

Ref: 02-J60453

Ipratropium bromide

CAS: 22254-24-6

Ipratropium bromide

Formula: C₂₀H₃₀BrNO₃H₂O

Purezza: 100.3%

Colore e forma: White

Peso molecolare: 429.15147

Ref: 47-625

Ipratropium-d3 Bromide

CAS: 22254-24-6

Formula: C₂₀H₂₇D₃NO₃·Br

Colore e forma: White To Off-White Solid

Peso molecolare: 335.48 79.90

Ref: 4Z-I-111

Ipratropium Bromide

CAS: 22254-24-6

Ipratropium Bromide

Purezza: ≥98%

Peso molecolare: 412.37g/mol

Ref: 54-BUP16104

Ipratropium-d3 Bromide(N-methyl-d3) marquée 22254-24-6

CAS: 22254-24-6

Purezza: 99 atom % D

Colore e forma: White Solid

Peso molecolare: 415.38

Ref: 3U-D6923

Ipratropium Bromide Monohydrate

CAS: 22254-24-6, 60205-81-4, 66985-17-9

Formula: C₂₀H₃₀BrNO₃·H₂O

Purezza: >98.0%(T)(HPLC)

Colore e forma: White to Almost white powder to crystal

Peso molecolare: 430.39

Ref: 3B-I0907

Ipratropium Bromide

CAS: 22254-24-6

Ipratropium Bromide (Sch 1000) is an antagonist of muscarinic receptors and is used in COPD and asthma studies.

Formula: C₂₀H₃₀BrNO₃

Purezza: 99.92%

Colore e forma: Solid

Peso molecolare: 412.37

Ref: TM-T6547

Ipratropium Bromide

Prodotto controllato

CAS: 22254-24-6

Applications Ipratropium Bromide is a nonselective muscarinic acetylcholine receptor antagonist; bronchodilator.
References Groeben, H., et al.: Anesthesiology, 85, 867 (1996); Haddad, et al.: Br. J. Pharmacol., 127, 413 (1999); Barnes, P. J., et al.: Chest, 117, 63S (2000)

Formula: C₂₀H₃₀NO₃·Br

Colore e forma: White

Peso molecolare: 412.36

Ref: TR-I740495

Ipratropium-d7 Bromide

Prodotto controllato

CAS: 22254-24-6

Applications N-Isopropyl quaternary salt of Atropine. Nonselective muscarinic acetylcholine receptor antagonist; bronchodilator.
References Groeben, H., et al.: Anesthesiology, 85, 867 (1996), Haddad, et al.: Br. J. Pharmacol., 127, 413 (1999), Barnes, P. J., et al.: Chest, 117, 63S (2000),

Formula: C₂₀H₂₃D₇BrNO₃

Colore e forma: Neat

Peso molecolare: 419.4

Ref: TR-I740503

Ipratropium bromide

CAS: 22254-24-6

Muscarinic antagonist

Formula: C₂₀H₃₀BrNO₃

Purezza: Min. 95%

Colore e forma: Powder

Peso molecolare: 412.36 g/mol

Ref: 3D-FI44992

Ipratropium bromide - Bio-X ™

CAS: 22254-24-6

Ipratropium is an ammonium derivative of atropine and acts as an anticholinergic drug that is used for the control of bronchospasms in chronic obstructive pulmonary disease (COPD). This drug is an antagonist of muscarinic acetylcholine receptors and produces an inhibitor of the parasympathetic system. As a result, this leads to bronchodilation and fewer bronchial secretions.

Formula: C₂₀H₃₀BrNO₃

Purezza: Min. 95%

Colore e forma: Powder

Peso molecolare: 412.36 g/mol

Ref: 3D-BI164579

(±)-Ipratropium-d3 Bromide (N-methyl-d3)

Prodotto controllato

CAS: 22254-24-6

Formula: C₂₀D₃H₂₇NO₃·Br

Colore e forma: Neat

Peso molecolare: 415.38

Ref: TR-I740501