CAS 2230496-80-5

ZL0420

CAS: 2230496-80-5

Formula: C₁₆H₁₆N₄O₂

Purezza: 98%

Peso molecolare: 296.3238

Ref: IN-DA01ENX1

ZL0420

CAS: 2230496-80-5

ZL0420 is a bromodomain inhibitor that binds to the bromodomain of toll-like receptor 3 (TLR3) and TLR4. ZL0420 has been shown to inhibit the response to TLR3 and TLR4 stimulation in vitro and in vivo in mice. This inhibition leads to a decrease in the production of inflammatory cytokines and chemokines, which reduces inflammation. ZL0420 also modulates the expression of genes involved in cancer development, mesenchymal transition, and muscle cell response. It inhibits the activity of a number of proteins including histone deacetylases, protein kinase C, NF-κB, JNK, TNF receptor I/II, TRAF6, Janus kinase 2 (JAK2), and phosphoinositide 3-kinase (PI3K). ZL0420 has not yet been tested for toxicity or efficacy in humans.

Formula: C₁₆H₁₆N₄O₂

Purezza: Min. 95%

Peso molecolare: 296.32 g/mol

Ref: 3D-FPD49680