CAS 2230821-38-0

SJF 1528

CAS: 2230821-38-0

Potent EGFR & HER2 degrader; DC50 of 39.2 nM in OVCAR8, 736 nM in HeLa; has lapatinib, VHL ligand; inhibits HER2+ breast cancer (IC50=102 nM for SKBr3).

Formula: C₅₅H₅₇ClFN₇O₈S

Colore e forma: Solid

Peso molecolare: 1030.61

Ref: TM-T36245

SJF 1528

CAS: 2230821-38-0

SJF 1528 is a potent kinase inhibitor that has shown promise in the treatment of various types of cancer. It is an analog of a medicinal plant-derived compound and has been found to inhibit tumor growth in Chinese hamster ovary cells and human cancer cell lines. SJF 1528 works by inhibiting the activity of specific kinases involved in cell replication, leading to apoptosis or programmed cell death. This protein inhibitor has been found to be effective against several types of cancer, including breast, lung, and colon cancers. SJF 1528 has also been detected in urine samples from patients receiving this drug for cancer treatment, indicating its potential as an anticancer agent.

Formula: C₅₅H₅₇ClFN₇O₈S

Purezza: Min. 95%

Peso molecolare: 1,030.6 g/mol

Ref: 3D-FPD82138